Category: Silicon Valley

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Europe warned to prepare for mpox as Pakistan reports first case

Stockholm — Health authorities warned Friday that Europe must be ready for more cases of a deadly strain of mpox that has killed hundreds of people in the Democratic Republic of Congo.

The World Health Organization urged pharmaceutical firms to ramp up vaccine production and China said it would screen travelers for the disease after the first cases of the more deadly strain to be recorded outside Africa were announced in Sweden and Pakistan.

France’s Prime Minister Gabriel Attal said his country was on the “highest alert” and would implement “new recommendations” for travelers to risk areas.

Mpox is caused by a virus transmitted to humans by animals but can also spread human-to-human through close physical contact.

It causes fever, muscular aches and large boil-like skin lesions.

The WHO on Wednesday declared the rapid spread of the new Clade 1b strain an international public health emergency — the agency’s highest alert.

This follows the spread of the more deadly mpox from Democratic Republic of Congo (DRC) to other African countries.

“We do need the manufacturers to really scale up so that we’ve got access to many, many more vaccines,” WHO spokesperson Margaret Harris told reporters.

The WHO is asking countries with vaccine stockpiles to donate them to countries with outbreaks.

Harris said mpox was “particularly dangerous for those with a weak immune system, so people who maybe have HIV or are malnourished,” and was also dangerous for small children.

The United States has said it will donate 50,000 doses of an mpox vaccine to DRC and Attal said France would also send vaccines to risk countries.

Danish drugmaker Bavarian Nordic said Thursday it would be ready to make up to 10 million doses of its mpox vaccine by 2025 but that it needed contracts to start production.

The Stockholm-based European Center for Disease Prevention and Control (ECDC) said the overall risk in Europe was “low.” But it warned that “effective surveillance, laboratory testing, epidemiological investigation and contact tracing capacities will be vital to detecting cases.”

“Due to the close links between Europe and Africa, we must be prepared for more imported clade I cases,” ECDC director Pamela Rendi-Wagner said in a statement.

Hundreds killed in DRC

The virus has swept across DRC, killing 548 people so far this year, the government said Thursday.

Nigeria has recorded 39 mpox cases this year, but no deaths, according to its health authorities. Previously unaffected countries such as Burundi, Kenya, Rwanda and Uganda have reported outbreaks, according to the Africa Centers for Disease Control and Prevention.

Sweden’s Public Health Agency announced Thursday it had registered a case of Clade 1b.

The patient was infected during a visit to “the part of Africa where there is a major outbreak of mpox Clade 1,” epidemiologist Magnus Gisslen said in a statement.

The mpox strain in the Pakistan case was not immediately known, the country’s health ministry said in a statement.

It said the patient, a 34-year-old man, had “come from a Gulf country.”

China announced it would begin screening people and goods entering the country for mpox over the next six months.

People arriving from countries where outbreaks have occurred, who have been in contact with mpox cases or display symptoms should “declare to customs when entering the country,” China’s customs administration said.

Vehicles, containers and items from areas with mpox cases should be sanitized, it added in a statement.

Vaccination drive

Mpox has two subtypes: the more virulent and deadlier Clade 1, endemic in the Congo Basin in central Africa; and Clade 2, endemic in West Africa.

A worldwide outbreak beginning in 2022 involving the Clade 2b subclade caused some 140 deaths out of about 90,000 cases, mostly affecting gay and bisexual men.

France reported 107 cases of the milder mpox variant between January 1 and June 30 this year.

The WHO’s European regional office in Copenhagen said the Sweden case was “a clear reflection of the interconnectedness of our world.”

But it added: “Travel restrictions and border closures don’t work and should be avoided.”

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Nigeria on ‘high alert’ amid surging cases of mpox in Africa

Abuja, Nigeria — Nigerian authorities on Thursday placed key entry points into the country on high alert following the outbreak of the mpox virus in Africa. Authorities have also put nine Nigerian states, including the commercial hub, Lagos, and the capital, Abuja, under serious surveillance.

The Nigerian Center for Disease Control and Prevention told journalists that the action is in response to surging cases of the mpox virus in Africa and to intensify coordination to limit importation and spread of the virus.

This week, the Africa Centers for Disease Control and Prevention said it had recorded 2,863 confirmed cases of mpox, with 517 deaths, across 13 countries this year. It said there are about 17,000 suspected cases of mpox, formerly known as monkeypox, in total.

So far this year, Nigeria has recorded 39 cases of mpox, with no deaths.

Jide Idris, head of the Nigerian CDC, said it’s best to be prepared.

“We’re intensifying surveillance activities by tracking cases across Nigeria to swiftly detect and respond to any new cases,” he said. “Along this line, five designated international airports, some key seaports … land and foot crossing borders have been placed in high alert. Declaration forms have been distributed to airlines where there’s an ongoing outbreak of mpox in the last 90 days.”

The Nigerian CDC said authorities are distributing diagnostic tools to states. They also have issued a public advisory on ways to prevent the spread of the mpox virus, including limiting contact with animals such as rodents and monkeys.

“We’re also considering vaccination efforts for high-risk groups, as Nigeria expects to receive about 10,000 doses of the new vaccines that have just recently been approved for emergency use,” Idris said. “We’re also meeting with collaborative agencies like Ministry of Environment and Agriculture for support and coordination efforts.”

Authorities say a new strain of the virus, which is more deadly and more easily transmitted, is responsible for the recent spread. The strain was first discovered in the Democratic Republic of Congo and later reported in Kenya, Rwanda and Uganda, all previously unaffected nations.

On Tuesday, the Africa CDC declared mpox a public health emergency of international-continental concern.

Jean Kaseya, head of the Africa CDC, said, “This declaration is not merely a formality. It’s a clarion call to action. It’s a recognition that we can no longer afford to be reactive; we must be proactive and aggressive in our effort to contain and eliminate this threat.”

Mpox is a viral disease that causes pus-filled lesions resembling rashes to appear on the skin.

In 2022, the World Health Organization declared it an international health emergency after cases were found in more than 70 countries.

Health analysts say the new strain is worrisome and will need a coordinated international response to control it and save lives.

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Mpox virus now in Pakistan, health authorities say

PESHAWAR, Pakistan — Pakistan’s health ministry has confirmed at least one case of the mpox virus in a patient who had returned from a Gulf country, it said on Friday, as provincial health authorities reported they had detected three cases.

A health ministry spokesperson said the sequencing of the confirmed case was under way, and that it would not be clear which variant of mpox the patient had until the process was complete.

A new form of the virus has triggered global concern because it seems to spread more easily though routine close contact.

Earlier on Friday, the health department in northern Khyber Pakhtunkhwa province said three cases had been detected in patients on arrival from the United Arab Emirates. It was not clear whether the patient confirmed by the central health ministry was among the three.

The World Health Organization has declared the recent outbreak of the disease as a public health emergency of international concern after the new variant of the virus was identified.

Health ministry spokesperson Sajid Shah said so far they had no confirmation of the new variant, but the sequencing of the sample of the confirmed patient was under way.

“Once that’s done, we will be able to say what strain is this,” said Shah.

Salim Khan, the director general of health services for Khyber Pakhtunkhwa, said three patients were in quarantine.

Global health officials on Thursday confirmed an infection with a new strain of the mpox virus in Sweden and linked it to a growing outbreak in Africa, the first sign of its spread outside the continent.

The WHO on Wednesday sounded its highest level of alert over the outbreak in Africa after cases in the Democratic Republic of Congo spread to nearby countries.

There have been 27,000 cases and more than 1,100 deaths, mainly among children, in Congo since the current outbreak began in January 2023.

The disease, caused by the monkeypox virus, leads to flu-like symptoms and pus-filled lesions. It is usually mild but can kill, with children, pregnant women and people with weakened immune systems, such as those with HIV, all at higher risk of complications.

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Restaurant with robot servers causes excitement in Nairobi     

In Nairobi, a new restaurant is generating business and buzz – not just because of the food, but because of the staff. Robots serving dishes is the main attraction of diners who flock to the Robot Cafe. Juma Majanga reports. Camera: Jimmy Makhulo.

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August’s supermoon kicks off four months of lunar spectacles

cape canaveral, florida — The first of four supermoons this year rises next week, providing tantalizing views of Earth’s constant companion.

Stargazers can catch the first act Monday as the full moon inches a little closer than usual, making it appear slightly bigger and brighter in the night sky.

“I like to think of the supermoon as a good excuse to start looking at the moon more regularly,” said Noah Petro, project scientist for NASA’s Lunar Reconnaissance Orbiter.

August’s supermoon kicks off a string of lunar spectacles. September’s supermoon will coincide with a partial lunar eclipse. October’s will be the year’s closest approach, and November’s will round out the year.

What makes a moon so super?

More a popular term than a scientific one, a supermoon occurs when a full lunar phase syncs up with an especially close swing around Earth. This usually happens only three or four times a year and consecutively, given the moon’s constantly shifting, oval-shaped orbit.

A supermoon obviously isn’t bigger, but it can appear that way, although scientists say the difference can be barely perceptible.

“Unless you have looked at a lot of full moons or compare them in images, it is hard to notice the difference, but people should try,” Petro said in an email.

How do supermoons compare?

There’s a quartet of supermoons this year.

The first will be 361,970 kilometers away. The next will be nearly 4,484 kilometers closer the night of September 17 into the following morning.

A partial lunar eclipse will also unfold that night, visible in much of the Americas, Africa and Europe as the Earth’s shadow falls on the moon, resembling a small bite.

October’s supermoon will be the year’s closest at 357,364 kilometers from Earth, followed by November’s supermoon at 361,867 kilometers.

What’s in it for me?

Scientists point out that only the keenest observers can discern the subtle differences. It’s easier to detect the change in brightness — a supermoon can be 30% brighter than average.

With the U.S. and other countries ramping up lunar exploration with landers and eventually astronauts, the moon beckons brighter than ever. As project scientist for the first team of moonwalkers coming up under Apollo’s follow-on program, Artemis, Petro is thrilled by the renewed lunar interest.

“It certainly makes it more fun to stare at,” Petro said.

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Google says Iranian group trying to hack US presidential campaigns

NEW YORK — Google said Wednesday that an Iranian group linked to the country’s Revolutionary Guard had tried to infiltrate the personal email accounts of roughly a dozen people linked to President Joe Biden and former President Donald Trump since May. 

The tech company’s threat intelligence arm said the group was still actively targeting people associated with Biden, Trump and Vice President Kamala Harris, who replaced Biden as the Democratic candidate last month when he dropped out of the presidential race. It said those targeted have included current and former government officials, as well as presidential campaign affiliates. 

The new report from Google’s Threat Analysis Group affirmed and expanded upon a Microsoft report released Friday that revealed a suspected Iranian cyber intrusion in this year’s U.S. presidential election. It shed light on how foreign adversaries are increasing their efforts to disrupt the election that is now less than three months away. 

Google’s report said its threat researchers detected and disrupted a “small but steady cadence” of the Iranian attackers using email credential phishing, a type of cyberattack where the attacker poses as a trusted sender to try to get an email recipient to share login details. John Hultquist, chief analyst for the company’s threat intelligence arm, said the company sends suspected targets of these attacks a Gmail pop-up that warns them that a government-backed attacker might be trying to steal their passwords. 

The report said Google observed the group gaining access to one high-profile political consultant’s personal Gmail account. Google reported the incident to the FBI in July. Microsoft’s Friday report had shared similar information, noting that the email account of a former senior adviser to a presidential campaign had been compromised and weaponized to send a phishing email to a high-ranking campaign official. 

The group is familiar to Google’s threat intelligence arm and other researchers, and this isn’t the first time it has tried to interfere in U.S. elections, Hultquist said. The report noted that the same Iranian group targeted both the Biden and Trump campaigns with phishing attacks during the 2020 cycle, as early as June of that year. 

The group also has been prolific in other cyber espionage activity, particularly in the Middle East, the report said. In recent months, as the Israel-Hamas war has fueled tension in the region, that activity has included email phishing campaigns targeted at Israeli diplomats, academics, nongovernmental organizations and military affiliates. 

Trump’s campaign said Saturday that it had been hacked and that sensitive internal documents had been stolen and distributed. It said Iranian actors were to blame. 

The same day, Politico revealed it had received leaked internal Trump campaign documents by email, though it wasn’t clear whether the leaked documents were related to the suspected Iranian cyber activity. The Washington Post and The New York Times also received the documents. 

While the Trump campaign hasn’t provided specific evidence linking Iran to the hack, both Trump and his longtime friend and former adviser Roger Stone have said they were contacted by Microsoft related to suspected cyber intrusions. Stone’s email was compromised by hackers targeting Trump’s campaign, a person familiar with the matter said. 

Google and Microsoft wouldn’t identify the people targeted in the Iranian intrusion attempts or confirm that Stone was among them. Google did confirm that the Iranian group in its report, which it calls APT42, is the same as the one in Microsoft’s research. Microsoft refers to the group as Mint Sandstorm. 

Harris’ campaign has declined to say whether it has identified any state-based intrusion attempts but has said it vigilantly monitors cyber threats and isn’t aware of any security breaches of its systems. 

The FBI on Monday confirmed that it’s investigating the intrusion of the Trump campaign. Two people familiar with the matter said the FBI also is investigating attempts to gain access to the Biden-Harris campaign. 

The reports of Iranian hacking come as U.S. intelligence officials have warned of persistent and mounting efforts from both Russia and Iran to influence the U.S. election through their online activity. Beyond these hacking incidents, groups linked to the countries have used fake news websites and social media accounts to churn out content that appears intended to sway voters’ opinions. 

While neither Microsoft nor Google specified Iran’s intentions in the U.S. presidential race, U.S. officials have previously hinted that Iran particularly opposes Trump. U.S. officials also have expressed alarm about Tehran’s efforts to seek retaliation for a 2020 strike on an Iranian general that was ordered by Trump. 

Iran’s mission to the United Nations, when asked about the claim of the Trump campaign, denied being involved. 

“We do not accord any credence to such reports,” the mission told The Associated Press. “The Iranian government neither possesses nor harbors any intent or motive to interfere in the United States presidential election.” 

The mission did not immediately respond to a request for comment Wednesday about Google’s report.

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Biden strikes $150M blow against cancer in campaign to slash deaths

washington — President Joe Biden on Tuesday visited Louisiana’s infamous “Cancer Alley” to strike at what he identified as a top priority of his dwindling presidency: announcing $150 million in research funding toward the goal of dramatically reducing cancer deaths in the United States.

The Cancer Moonshot is an initiative close to Biden’s heart. Both he and first lady Jill Biden have had brushes with skin cancers. And in 2015, an aggressive brain cancer took the life of their eldest son, Beau.

“We’re moving quickly,” Biden said of the initiative, which has a goal of reducing the U.S. cancer death rate by at least half by 2047. “Because we know that all families touched by cancer are in a race against time.”

Cancer is the second-biggest cause of death worldwide. The National Cancer Institute predicts that 2 million Americans will be diagnosed this year with the immune-mediated disease, which can manifest in organs, bone marrow and blood and which comes in hundreds of different varieties.

“Cancer touches us all,” the first lady said. “When Joe and I lost our son to brain cancer, we decided to turn our pain into purpose. We wanted to help families like ours so that they won’t have to experience this terrible loss, and as president, Joe has brought his own relentless optimism to the Biden Cancer Moonshot to end cancer as we know it. It’s ambitious, but it’s also within our reach – maybe not yet, but one day soon.”

Biden launched the initiative when he was vice president. Since he restored the program as president, the research agency he created has invested more than $400 million in the cause.

Cancer advocates praised the move but stressed the need for long-term engagement.

“We’ve made tremendous strides in how we prevent, detect, treat and survive cancer, but there is still much work to be done to improve the lives of those touched by this disease,” said Dr. Karen E. Knudsen, CEO of the American Cancer Society and the American Cancer Society Cancer Action Network.

“Cancer cases are estimated to hit an all-time high this year, and we cannot relent in driving forward public policies that will address this,” Knudsen said. “Funding more researchers across the country focused on more effective and innovative treatments will bring us closer to future cancer breakthroughs and ending cancer as we know it, for everyone.”

And cancer is often compounded by environmental causes – such as those in the 140-kilometer (85-mile) stretch of communities between Baton Rouge and New Orleans, home to a string of major fossil fuel and petrochemical operations.

Karl Minges, associate dean in the School of Health Sciences at the University of New Haven, told VOA that while the disease itself doesn’t discriminate, social factors often make it hit harder in lower-income communities.

“Any time that money from the federal government and publicity is put on a topic, I think it’s something that has the ability to actually make a significant difference,” he told VOA.

And, he said, the fact that this federal money is going toward research institutions – and not private pharmaceutical companies – means the lessons learned can be shared well beyond the United States.

“The U.S. is always on sort of the cutting edge with regard to [research and development] of new drugs and treatments and methodologies,” he said.

“But by giving the money to the institutes, it’s sort of available as public funding for researchers to access, and anytime that’s the case, there’s an imperative, whether it’s a clinical trial or it’s a an observational study, that the results are in the public domain, so that can be then subsumed by other countries outside of the United States who face similar issues,” Minges said.

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Australian researchers herald new groundbreaking diabetes drug

SYDNEY — Researchers in Australia have developed a drug that could revolutionize treatment for millions of diabetes patients around the world.  

Scientists in the U.S., China and Australia are designing treatments that imitate the body’s natural response to changing blood glucose, or sugar, levels and respond instantly.  

The Australian team is handling one of several research projects that have developed different types of so-called ‘smart insulins,’ which sits in the body of a diabetes patient and is activated only when it is needed. 

The aim is to keep glucose levels within a safe range, avoiding excessively high blood glucose, which is called hyperglycaemia, and excessively low blood sugar levels, known as hypoglycaemia.    

The new treatments are not cures for diabetes but could ease the burden on patients.

Australian researchers say their new insulin delivery method would offer one injection every three days. Patients currently have to administer synthetic insulin up to 10 times a day.

Christoph Hagemeyer, a professor at the Australian Center for Blood Diseases at Monash University and a lead researcher in the study, told Australian Broadcasting Corp. Tuesday how the technology works.

“Smart insulin is responding to sugar levels in the blood,” he said. “In our case we are not actually making the insulin molecule smart, but we are loading the insulin onto a nanoparticle, which has a built-in mechanism that it changes its charge from positive to negative when the sugar levels go up. And that is the trick how we can ensure that there is enough insulin onboard and it is released in a smart manner.”   

Insulin is a type of hormone that lowers the level of glucose in the blood. Glucose is a type of sugar from food that gives people energy.

Diabetes affects glucose levels in the blood and is normally split into type 1 and type 2, the most common.  Patients have a heightened risk of heart attack, stroke, and kidney failure.  

Monash University in Melbourne is part of a global effort to develop different types of smart insulins. It includes teams at Stanford University in the United States and Zhejiang University in China.  Each project aims to develop smart insulin to act faster and more accurately to help patients with diabetes and to start trials as soon as possible.  

The World Health Organization has estimated that about 422 million people around the world have diabetes and that 1.5 million deaths are directly attributed to the chronic disease each year. 

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