Category: Silicon Valley

Silicon valley news. Silicon Valley is a region in Northern California that is a global center for high technology and innovation. Located in the southern part of the San Francisco Bay Area, it corresponds roughly to the geographical area of the Santa Clara Valley

Twitter Temporarily Closes Offices as Layoffs Begin

Twitter Inc temporarily closed its offices on Friday after telling employees they would be informed by email later in the day about whether they are being laid off.

The move follows a week of uncertainty about the company’s future under new owner Elon Musk.

The social media company said in an email to staff it would tell them by 9 a.m. Pacific time on Friday (12 p.m. EDT/1600 GMT) about staff cuts.

“In an effort to place Twitter on a healthy path, we will go through the difficult process of reducing our global workforce on Friday,” said the email sent on Thursday, seen by Reuters.

Musk, the world’s richest person, is looking to cut around 3,700 Twitter staff, or about half the workforce, as he seeks to slash costs and impose a demanding new work ethic, according to internal plans reviewed by Reuters this week.

The company’s content moderation team is expected to be a target of the cuts, tweets from Twitter employees suggested on Friday. Musk has promised to restore free speech while preventing it from descending into a “hellscape.”

Twitter did not immediately respond to a request for comment.

Twitter employees vented their frustrations about the layoffs on the social network, using the hashtag #OneTeam.

User Rachel Bonn tweeted: “Last Thursday in the SF (San Francisco) office, really the last day Twitter was Twitter. 8 months pregnant and have a 9 month old. Just got cut off from laptop access.”

Responding to the #OneTeam thread, Twitter’s Head of Safety & Integrity Yoel Roth, said: “Tweeps: My DMs (direct message routes) are always open to you. Tell me how I can help.”

Roth was the most senior executive to message publicly with a tweet of support for staff who are losing their jobs. He also appeared to still have his job. Last week, Musk endorsed Roth, citing his “high integrity” after he was called out over tweets critical of former U.S. President Donald Trump years earlier.

Roth did not respond to a request for comment.

Twitter said in the email that its offices would be temporarily closed and all badge access suspended in order “to help ensure the safety of each employee as well as Twitter systems and customer data.”

The company’s office in Piccadilly Circus, London, appeared deserted on Friday, with no employees in sight.

Inside, any evidence the social media giant had once occupied the building had been erased. Security staff said there were ongoing refurbishments, refusing to comment further.

The company said employees who were not affected by the layoffs would be notified via their work email addresses. Staff who had been laid off would be notified with next steps to their personal email addresses, the memo said.

A member of security staff at Twitter’s EMEA headquarters in Dublin told reporters that nobody was coming into the office on Friday and employees had been told to stay home.

Another member of the security staff locked the revolving doors at the front of the building where around 500 members of staff worked before the layoffs began.

Some employees tweeted their access to the company’s IT system had been blocked and feared that suggested they had been laid off.

“Looks like I’m unemployed y’all. Just got remotely logged out of my work laptop and removed from Slack,” tweeted a user with the account @SBkcrn, whose profile is described as former senior community manager at Twitter.

A class action lawsuit was filed on Thursday against Twitter by its employees, who argued the company was conducting mass layoffs without providing the required 60-day advance notice, in violation of federal and California law.

The lawsuit also asked the San Francisco federal court to issue an order to restrict Twitter from soliciting employees being laid off to sign documents without informing them of the pendency of the case.

Musk has directed Twitter’s teams to find up to $1 billion in annual infrastructure cost savings, according to two sources familiar with the matter and an internal Slack message reviewed by Reuters.

He has already cleared out the company’s senior ranks, firing its chief executive and top finance and legal executives. Others, including those sitting atop the company’s advertising, marketing and human resources divisions, have departed throughout the past week.

Musk’s first week as Twitter’s owner has been marked by chaos and uncertainty. Two company-wide meetings were scheduled, only to be canceled hours later. Employees told Reuters they were left to piece together information through media reports, private messaging groups and anonymous forums.

The layoffs, which were long expected, have chilled Twitter’s famously open corporate culture that has been lauded by many of its employees.

“If you are in an office or on your way to an office, please return home,” Twitter said in the email on Thursday.

Shortly after the email landed in employee in boxes, hundreds of people flooded the company’s Slack channels to say goodbye, two employees told Reuters. Someone invited Musk to join the channel, the sources said.

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Australia Warns of New COVID Surge

Australia can expect another wave of COVID-19 infections in coming weeks, according to experts, as new variants circulate. Coronavirus cases are rising quickly in New South Wales and Victoria, Australia’s most populous states.

The World Health Organization declared COVID-19 a global pandemic on March 11, 2020. The declaration is still active.

In Australia, life is resembling what it was before the virus. Most disease-control measures, such as mandatory mask-wearing on public transport and self-isolation for people testing positive to COVID-19, have been scrapped. Some restrictions, however, still apply to health, disability and aged-care facilities.

Public health authorities in the states of New South Wales and Victoria have warned that another surge in infections is approaching. Official data has shown that in the last week of October, coronavirus case numbers increased in all Australian states and territories except Queensland.

There were 9,707 positive diagnoses in the week ending Oct. 29 in New South Wales, an 11% increase from the previous week.

Government data has shown that more than 95% of Australians over 16 have had at least two doses of a COVID-19 vaccine.

In a video posted on Twitter on Thursday, New South Wales Chief Health Officer Kerry Chant warned of a spike in infections.

“By looking at all the local information we have and what is happening overseas we believe COVID cases will rise in the coming weeks,” Chant said. “The protection the New South Wales community has from vaccination and previous infection continues to reduce the risk of severe illness. However, the elderly and those with underlying health conditions will continue to be at higher risk.”

COVID-19 continues to spread in other countries.

China’s COVID-19 cases hit their highest in 2½ months Thursday, according to health authorities. The world’s most populous nation is following President Xi Jinping’s zero-COVID policy, which has seen millions of people locked down in major cities. The WHO has said China has had more than 9 million confirmed coronavirus cases since the pandemic began.

In the United States, White House chief medical adviser Dr. Anthony Fauci said Thursday that new omicron variants were gaining ground across the country as winter approaches.

Researchers at University College London say Britain could be relatively free of COVID-19 this Christmas but potentially faces another wave of cases in January.

The European Centre for Disease Prevention and Control has said COVID-19 variants BQ.1 and BQ.1.1 are likely to drive up cases in the months ahead in Europe.

As of Thursday, there have been more 628 million confirmed COVID-19 cases globally, including about 6.5 million deaths reported to the WHO.

Isolation has helped to protect some communities from the virus. The WHO said that Niue, a small island in the South Pacific Ocean with a population of 2,000, has recorded 85 COVID-19 cases and no fatalities during the pandemic.

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Report: Tanzania’s Elephant Population Recovering 

Tanzania’s Ministry of Tourism released a census this week showing the country’s elephant population has stabilized.

Tanzania’s elephants were among the hardest hit by poaching in Africa, with numbers dropping 60 percent between 2009 and 2014. But authorities say joint efforts with conservation groups and local communities have drastically reduced poaching and helped to attract tourist dollars.

Just under 20,000 elephants were recorded in a survey that covered about 90,000 square kilometers of the Katavi-Rukwa and Ruaha-Rungwa landscapes in western Tanzania, including parks, game reserves and other protected areas.

The government said the results confirm that the landscape remains the most important in East Africa in terms of elephant numbers and contains the largest population on the continent outside Zimbabwe and Botswana.

Ernest Mjingo, a managing director of the Tanzania Wildlife Research Institute, a department of the Ministry of Tourism, said the world would now see Tanzania as very serious about conservation and doing well at it. And if the world does see that, he said, it would be a credit to the government and would also increase revenue, because Tanzania will become a prime destination for tourists because of the animal population. He added that it could also become a U.N. World Heritage Site, since it would have species that would not be available in other places.

The report said poaching had dramatically decreased over the last few years.

In the last report, conducted in 2018, the ratio of elephant carcasses to live animals was 14 percent. Now, it’s just 1.4 percent, thanks to government and stakeholders’ efforts in strengthening wildlife protection.

Tourism experts such as Makubi Mabula see the results of the census as a good sign for Tanzania’s economic prospects.

“Honestly, the results show a green light toward the future of tourism in our country,” he said through a translator. ” … Many tourists come to see animals like elephants, lions, rhinos and others. So, with the elephant population stabilizing, the national income will increase. It really gives us the peace we tourist stakeholders need to believe that the tourism industry will grow fast.”

Along with elephants, the survey also confirmed that the populations of 25 other key mammal species in Tanzania have stabilized, including buffaloes, zebras, hartebeests, impalas and giraffes.

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SpaceX Scores Style Points, Sends Secret Satellites to Space

A private spaceflight giant has a busy week sending satellites into orbit. Plus, massive meteor strikes on Mars, and the Pillars of Creation get an eerie makeover. VOA’s Arash Arabasadi brings us The Week in Space.

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Explainer: Why the Black Sea Grain Deal Is Vital for Global Food Security

A landmark deal to allow grain exports from Ukraine, which was back on track Wednesday after being briefly suspended, has played a crucial role in easing a global food crisis sparked by the Russian invasion of Ukraine.

Brokered by the United Nations and Turkey and signed by Moscow and Kyiv on July 22, the agreement established a protected sea corridor to allow grain shipments to resume for the first time since the fighting began in February

Here is what we know about the deal, known as the Black Sea Grain Initiative:

Why was it needed?

When Russian troops attacked in late February, Moscow imposed a blockade on Ukraine’s Black Sea ports, halting all agricultural exports from one of the world’s breadbaskets.

The move left 20 million metric tons of grain stranded in Ukraine’s ports, causing food prices to surge worldwide.

Before the war, up to 90% of Ukraine’s wheat, corn and sunflower exports were transported by sea, mostly from Odesa, with many developing countries relying heavily on Kyiv for grain.

Agricultural commodity prices were high before the war because of the post-COVID-19 economic recovery, but the conflict pushed the price of grains such as wheat and corn to levels unsustainable for countries dependent on their import, such as Egypt, Lebanon and Tunisia.

What does the deal cover?

The deal ensures the safe export of grain, foodstuffs and fertilizers, including ammonia, from three Black Sea ports in southwestern Ukraine: Odesa, Chornomorsk and Pivdennyi.

The first grain ship to leave under the U.N.-backed deal set sail on August 1.

According to U.N. figures as of November 1, a total of 9.7 million metric tons of grain and other agricultural products have been transported in the first three months of the initiative, the vast majority involving wheat and corn.

Valid for 120 days, the agreement is up for renewal on November 19 in a process that can be done automatically without further negotiations.

The U.N. says extending the deal is crucial for global food security and is pushing for it to be renewed for one year.

Although the initiative is working well, shipments are about 40-50% lower than what they were before Russia’s invasion, the U.N. says.

How does it work?

According to the U.N.’s website, the agreement establishes a safe corridor between the three Ukrainian ports and an area in Turkish waters where the vessels are inspected before being allowed to continue their journey.

To monitor the agreement, a joint command and control center was set up in Istanbul to oversee smooth operations and resolve disputes.

Known as the Joint Coordination Center (JCC), the JCC has four teams of eight inspectors — two each from Russia, Ukraine, Turkey and the U.N.

These teams inspect outbound vessels carrying grain at the Turkish inspection area to ensure all merchandise is approved.

The teams also examine empty ships returning to Ukraine to ensure they are not carrying any weapons or other unauthorized goods or people.

Safe passage

The deal establishes a buffer zone of 10 nautical miles around each vessel traveling along the corridor with no military ships, equipment or drones allowed within that radius.

All ship movements logged by the JCC are transmitted to the relevant military authorities to prevent any incidents, with any violations or threats to be handled by the JCC.

At the start of the war, Ukraine mined its main Black Sea ports to head off threats of a Russian attack from the sea, but experts said it would take too long to de-mine all these areas.

The deal allows Ukrainians to guide the ships along safe routes that avoid known mine fields and into and out of its territorial waters.

Deal briefly suspended

On October 29, Russia said it was suspending its participation in the deal, accusing Ukraine of using the shipping corridor to launch a drone attack on its Black Sea fleet in Crimea’s Sevastopol port.

After a call between the Russian and Turkish defense ministers, the deal resumed operation at 0900 GMT on November 2 with Moscow saying it had received written guarantees from Kyiv ensuring the corridor would not be used for attacking Russian forces.

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Report: Europe Warms More Than Any Other Continent in Last 3 Decades 

Europe has warmed more than twice as much as the rest of the world over the past three decades and has experienced the greatest temperature increase of any continent, according to a report by the World Meteorological Organization. 

The report on the state of the climate in Europe follows a summer of extremes. A record-breaking heat wave scorched Britain, Alpine glaciers vanished at an unprecedented rate and a long-lasting marine heat wave cooked the waters of the Mediterranean.  

“Europe presents a live picture of a warming world and reminds us that even well-prepared societies are not safe from impacts of extreme weather events,” WMO secretary-general Petteri Taalas said in a statement.  

From 1991 to 2021, temperatures over Europe warmed at an average of 0.5 degree Celsius per decade, the report said, while the global average was just 0.2 degree C. 

Last year, extreme weather events made worse by climate change — chiefly floods and storms — caused more than $50 billion worth of damage in Europe. 

The reason Europe is warming faster than other continents has to do with the fact that a large part of the continent is in the sub-Arctic and Arctic — the fastest-warming region on Earth — as well as changes in climate feedbacks, scientists said. 

For example, fewer clouds over Europe during the summer has meant that more sunlight and heat now reaches the continent, said Freja Vamborg, senior scientist with the Copernicus Climate Change Service. 

Some scientists have called Europe a “heat wave hot spot” as the number of heat waves on the continent has increased faster than in other regions because of changes in atmospheric circulation.  

Although temperatures are rising, the European Union has cut greenhouse gas emissions by 31% between 1990 and 2020, the report said, and it aims to slash emissions by 55% by 2030.  

On November 6, delegates will arrive in Egypt for COP27, the annual U.N. climate summit. 

French President Emmanuel Macron and European Commission President Ursula von der Leyen are expected to attend. British Prime Minister Rishi Sunak’s decision not to attend the COP27 climate summit is being kept under review, his spokesman said Monday.

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Activists Welcome India’s Ban on ‘Two-Finger’ Test on Rape Survivors

Advocacy groups are welcoming a decision by India’s Supreme Court that bans what is known as a “two-finger” test on rape survivors, calling it a patriarchal and invasive practice and ruling that anyone violating the directive will face misconduct charges.

Medical experts have used the test to determine whether a woman has engaged in regular sexual intercourse.

Calling the practice regressive and unscientific, a two-judge panel said, “the probative value of a woman’s testimony does not depend upon her sexual history. It is patriarchal and sexist to suggest that a woman cannot be believed when she states that she was raped, merely for the reason that she is sexually active.”

New York-based Human Rights Watch said in a statement, “The judgment brings hope that the justice system will finally stop using this unscientific process.”

In the past, the Supreme Court had “deprecated,” or voiced disapproval of, the use of the test in several orders, Justice DY Chandrachud, one of the two judges, noted.

“The so-called test has no scientific basis. It instead re-victimizes and re-traumatizes women and is an affront to their dignity. So, the two-finger or per vaginam test must not be conducted,” Chandrachud said.

“The test is based on an incorrect assumption that a sexually active woman cannot be raped. Nothing can be further from the truth — evidence of a victim’s sexual history is wholly immaterial while adjudicating whether the accused raped her. It is regrettable that it continues to be conducted even today.”

The bench made the observation while restoring conviction in a 2004 case of rape and murder of a woman in the eastern state of Jharkhand. On October 31, the Supreme Court overturned a ruling by the Jharkhand High Court acquitting a man — who had been previously convicted by a lower-level trial court in the state.

The Supreme Court asked the federal and state governments to ensure that the two-finger test is no longer conducted on rape survivors. The court ordered the Indian health ministry to conduct workshops for all health service providers across the country, in order to communicate the proper procedure to examine rape survivors and let them know that in no situation are they to conduct two-finger tests.

The court also ordered the health ministry to ensure that the chapter on two-finger tests is removed from the syllabus of medical education.

Since 2013, the Supreme Court has said the test and its interpretation violate the right of rape survivors to privacy, physical and mental integrity, and dignity. Indrajit Khandekar, a Maharashtra state-based activist and medical doctor, said this is the first time the court has banned it and attached punitive action on doctors found conducting the test.

Khandekar, a forensic expert, filed a public interest litigation in the Bombay High Court in 2010 seeking a ban on the test on the basis of a 258-page report that he prepared following his research on the use of the test.

The attachment of the provision of punishment in Monday’s ruling from the country’s highest court raises hopes the test will finally be eliminated, Khandekar said.

“The two-finger test or the virginity test is an unscientific, inhumane, derogatory, and discriminatory practice that violates a woman’s dignity,” Khandekar told VOA. “The test can be physically, psychologically, and socially devastating to girls or young women. Other people have no right to know whether or not a particular girl is a virgin.”

In several cases, the doctor’s opinion after conducting a two-finger test, and the assumption that a rape survivor had engaged in regular sexual activity, was used to cast a stigma on a young woman’s character, calling her one with bad morals, he said.

“As a result, one might wonder whether this is a trial for rape on a woman or a trial for the victim’s character. Even the insertion of the fingers into the vagina of a female without her consent is nothing but a second assault,” Khandekar said.

Medical doctor Ranjana Pardhi, who has long campaigned against the two-finger test, said that studies published in several medical journals show that the inspection of the hymen cannot give conclusive evidence of vaginal penetration or any other sexual history.

“Abnormal hymenal features such as a hymenal transection, laceration, enlarged opening, or scars are found in females with, as well as without, a history of sexual intercourse. Vaginal laxity and size of introitus [an opening] also is not an indicator of sexual intercourse. There are some other tests to confirm sexual intercourse or penetration,” Nagpur-based Pardhi told VOA.

“The so-called virginity test or two-finger test is medically flawed.”

Pardhi added that activists campaigning against the test are hopeful that their long fight is going to bear fruit but warned that without enforcement, it might not be successful

“We also hope that the law enforcement agencies and the judiciary will strictly penalize the medical professionals for noncompliance. Otherwise, the ban will remain unimplementable and meaningless,” she said.

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UN: Agricultural Automation Can Boost Global Food Production

A new U.N. report finds agricultural automation can boost global food production and be a boon for small-scale farmers in developing countries.

The U.N. Food and Agriculture Organization, FAO, has just released The State of Food and Agriculture 2022 report. The report’s authors said automation is rapidly changing the face of agriculture. New technologies, they say, are quickly leaving behind some of the old larger-type tractors and large machinery in ways that could benefit small holders in developing countries.

Parallels can be drawn with the introduction of cellphones. The World Bank, among other observers, notes African and other developing countries can harness digital technologies to boost their economies by advancing from landlines to smartphones.

FAO said automation can play an important role in making food production more efficient and more environmentally friendly.

Chief FAO economist Maximo Torero said many emerging technologies would have been unimaginable years ago. He cited as examples fruit-picking robots that use artificial intelligence and sensors that monitor plants and animals.

“Automation allows agriculture to be more productive, efficient, resilient, and sustainable and can improve working conditions,” Torero said. “However, as with any technological change, automation also implies disruption to the agricultural systems. The risk is that the automation could exacerbate inequalities if we are not careful on how it is being done and developed and deployed.”

The report looks at 27 case studies from all over the world. They represent technologies at different stages of readiness suitable for large or small agricultural producers of varying levels of income.

Torero said the report investigates the drivers of these technologies and identifies barriers preventing their adoption, particularly by small-scale producers. The report, he said, also looks at one of the most common concerns about automation — that it creates unemployment.

“While it concludes that such fears are overblown, it acknowledges that agricultural automation can lead to unemployment in places where rural labor is abundant, and wages are low,” he said. “It is important to understand that in a continent like sub-Saharan Africa, where there is an enormous amount of youth population, we can build the skill sets of these people to be able to have access to these technologies.”

In areas where cheap labor is abundant, the FAO urges policymakers to avoid subsidizing automation while creating an enabling environment for its adoption. At the same time, the report said governments should provide social protection to the least skilled workers who are likely to lose their jobs during the transition.

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COP27: Will Ukraine War Destroy Progress on Tackling Climate Emergency?

Ahead of the COP27 climate talks in the Egyptian resort of Sharm el-Sheikh next week, there are concerns that Russia’s invasion of Ukraine has reversed progress on tackling climate change. But as Henry Ridgwell reports, some say the war could have a positive impact in the longer term

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US Pharmacy Chains Reach Tentative Opioid Settlement

Three of the largest U.S. pharmacy chains — CVS, Walgreens and Walmart — are reported to have tentatively agreed to pay more than $13 billion to settle more than 3,000 state and local lawsuits involving the dispensing of opioid painkillers. 

Sources close to the negotiations report CVS will pay $5 billion over 10 years, Walgreens will pay $5.7 billion over 15 years and Walmart will pay $3.1 billion, mostly up front. The sources remained anonymous as they were not authorized to speak publicly about the agreement. 

 

In a statement released Wednesday, CVS Health said it has agreed it will pay approximately $5 billion — with $4.9 billion to states and political subdivisions and approximately $130 million to Native American tribes — over the next 10 years beginning in 2023. 

In the statement, CVS Health Chief Policy Officer and General Counsel Thomas Moriarty said, “We are committed to working with states, municipalities and tribes, and will continue our own important initiatives to help reduce the illegitimate use of prescription opioids.”  

The CVS statement included a list of initiatives it has undertaken to fight opioid abuse.  

In the lawsuits, governments said pharmacies were filling prescriptions they should have flagged as inappropriate. 

If the settlement is finalized, it would be the first nationwide deal with retail pharmacy companies and follows nationwide opioid settlements with drugmakers and distributors totaling more than $33 billion. 

Opioids are natural, synthetic, or semi-synthetic chemicals used to reduce the intensity of pain signals and feelings of pain. The class of drugs includes the illegal drug heroin, synthetic opioids such as fentanyl, and pain medications available legally by prescription, such as oxycodone, hydrocodone, codeine, morphine, and many others. 

The U.S. Centers for Disease Control and Prevention reports that from 1999 to 2020, more than 564,000 people in the U.S. died from an overdose involving an opioid, including prescription and illicit opioids. They report 187 people in the U.S. continue to die from an opioid overdose every day. 

The Associated Press and Reuters provided some information for this report. 

 

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Strong RSV Vaccine Data Lifts Hopes After Years of Futility

New research shows vaccinating pregnant women helped protect their newborns from the common but scary respiratory virus called RSV that fills hospitals with wheezing babies each fall.

The preliminary results buoy hope that after decades of failure and frustration, vaccines against RSV may finally be getting close.

Pfizer announced Tuesday that a large international study found that vaccinating moms-to-be was nearly 82% effective at preventing severe cases of RSV in their babies’ most vulnerable first 90 days of life. At age 6 months, the vaccine still was proving 69% effective against serious illness — and there were no signs of safety problems in mothers or babies.

“Moms are always giving their antibodies to their baby,” said virologist Kena Swanson, Pfizer’s vice president of viral vaccines. “The vaccine just puts them in that much better position” to form and pass on RSV-fighting antibodies.

The vaccine quest isn’t just to protect infants. RSV is dangerous for older adults, too, and both Pfizer and rival GSK recently announced that their competing shots also proved protective for seniors.

None of the findings will help this year when an early RSV surge already is crowding children’s hospitals. But they raise the prospect that one or more vaccines might become available before next fall’s RSV season.

“My fingers are crossed,” said Dr. William Schaffner, an infectious disease specialist at Vanderbilt University. “We’re making inroads.”

Tuesday’s data was reported in a press release and hasn’t been vetted by independent experts.

Here’s a look at the long quest for RSV vaccines.

What is RSV?

For most healthy people, RSV, or respiratory syncytial virus, is a cold-like nuisance. But for the very young, the elderly and people with certain health problems, it can be serious, even life-threatening. The virus can infect deep in the lungs, causing pneumonia, and in babies, it can impede breathing by inflaming tiny airways.

In the U.S., about 58,000 children younger than 5 are hospitalized for RSV each year, and several hundred die. Among adults 65 and older, about 177,000 are hospitalized with RSV and 14,000 die annually.

Worldwide, RSV kills about 100,000 children a year, mostly in poor countries.

Why is there no vaccine?

A tragedy in the 1960s set back the whole field. Using the approach that led to the first polio vaccine, scientists made an experimental RSV vaccine by growing the virus in a lab and killing it. But testing in children found not only was the vaccine not protective, youngsters who caught RSV after vaccination fared worse. Two died.

“For a period of 20 years, even though science was advancing, nobody wanted to go near development of an RSV vaccine,” Schaffner said.

Even today’s modern RSV vaccine candidates were tested first in older adults, not children, he noted.

How did development get back on track?

Modern vaccines tend to target the outer surface of a virus — what the immune system sees when a germ invades. For RSV, that target is the so-called F protein that helps the virus latch onto human cells. Again, there was a hurdle: That protein is a shape-shifter, rearranging its form before and after it “fuses” to cells.

It turns out that the immune system only forms effective RSV-fighting antibodies when it spots what’s called the pre-fusion version of that protein, explained structural biologist Jason McLellan of the University of Texas at Austin.

In 2013, McLellan and virologist Barney Graham were working at the National Institutes of Health when they homed in on the correct shape and figured out how to freeze it in that form. That finding opened the way to today’s development of a variety of experimental RSV vaccine candidates.

(That same discovery was key to the hugely successful COVID-19 vaccines, as the coronavirus also is cloaked in a shape-shifting surface protein.)

What’s in the pipeline?

Several companies are creating RSV vaccines, but Pfizer and GSK are furthest along. Both companies recently reported final-stage testing in older adults. The competing vaccines are made somewhat differently but each proved strongly effective, especially against serious disease. Both companies plan to seek regulatory approval in the U.S. by the end of the year, as well as in other countries.

The older-adult data “looks fantastic,” said McLellan, who has closely followed the vaccine development. “I think we’re on the right track.”

And if vaccinating pregnant women pans out, it could be “a win for two individuals instead of just one,” by offering protection to both mom-to-be and baby, said Dr. Wilbur Chen of the University of Maryland School of Medicine.

Pfizer’s maternal vaccine is the same recipe that it tested successfully in older adults — and it also plans to seek Food and Drug Administration approval for those vaccinations by year’s end.

The new study included 7,400 pregnant women in 18 countries, including the U.S., and spanned multiple RSV seasons. Preliminary results reported Tuesday show the vaccine was most effective against severe disease. For milder illness, effectiveness was 51% to 57% — short of the study’s statistical requirements but a result that Pfizer still called clinically meaningful because it could mean fewer trips to the doctor’s office.

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Battling Cholera, Lebanon Gets First Vaccines, Sharp Words, From France

Lebanon received a first batch of vaccines Monday to combat a worsening cholera outbreak – together with sharply worded criticism of its crumbling public health infrastructure from France, which facilitated the donation of the doses.

By Sunday, cases of cholera – a disease typically spread through contaminated water, food or sewage – stood at 1,447, with 17 deaths, since the first were recorded in the country a month ago, Lebanon’s health ministry said.

Lebanon had been cholera-free since 1993, but its public services are suffering under a brutal economic crisis now in its fourth year, while infighting among the country’s faction-riven elite has paralyzed its political institutions.

The outbreak has reached Beirut, but authorities say most cases remain concentrated where it started in the northern town of Bebnine, where health authorities have set up an emergency field hospital.

The vaccines would play “an essential role” in limiting the disease’s spread, Health Minister Firass Abiad told reporters in the capital as he announced the first batch.

Standing next to Abiad, French ambassador Anne Grillo said the delivery comprised more than 13,000 doses. They had been donated by the philanthropic arm of French health care company Sanofi and the French government had facilitated their arrival to Lebanon.

“The origins of this epidemic, in which public health is at stake, must also be treated,” Grillo told reporters. The outbreak was “a new and worrying illustration of the critical decline in public provision of access to water and sanitary services in Lebanon.”

In the Bebnine field hospital, two young boys sat next to each other on one hospital bed, while a mother waited anxiously to confirm if her son, lying limp on another bed and being treated by a doctor and a nurse, had also caught the disease.

Nearby, Syrian children in a makeshift refugee camp played in dirty water chocked with rubbish and medical waste and fed by an outflow from an open pipe.

The World Health Organization has linked cholera’s comeback in Lebanon to an outbreak in neighboring Syria, to where it had spread from Afghanistan via Iran and Iraq.

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LogOn: Experts Worry Digital Footprints Will Incriminate US Patients Seeking Abortions

The U.S. Supreme Court’s overturning of protections for abortion rights has intensified scrutiny of the personal data that technology firms collect. For women who live in states where most abortions are now illegal, their smartphones and devices could be used against them. Tina Trinh reports. Camera: Saqib Ul Islam, Greg Flakus

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Ag App Connects Small Farmers and Buyers

Small farmers produce about one-third of the world’s food. Yet they lack global visibility and face many obstacles getting their crops to larger markets.  A new app is helping to change that for some farmers in Africa. VOA’s Julie Taboh has more. Camera, production: Adam Greenbaum

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Antibody Treatment Tested as New Tool Against Malaria

Research in Africa found a one-time dose of an experimental drug protected adults against malaria for at least six months, the latest approach in the fight against the mosquito-borne disease. 

Malaria killed more than 620,000 people in 2020 and sickened 241 million, mainly children under 5 in Africa. The World Health Organization is rolling out the first authorized malaria vaccine for children, but it is about 30% effective and requires four doses. 

The new study tested a very different approach — giving people a big dose of lab-made malaria-fighting antibodies instead of depending on the immune system to make enough of those same infection-blockers after vaccination.

“The available vaccine doesn’t protect enough people,” said Dr. Kassoum Kayentao of the University of Sciences, Techniques and Technologies in Bamako, Mali, who helped lead the study in the villages of Kalifabougou and Torodo. 

In those villages during malaria season, other research has shown, people are bitten by infected mosquitoes on average twice a day. 

The experimental antibody, developed by researchers at the U.S. National Institutes of Health, was given by IV — difficult to deliver on a large scale. But the encouraging findings bode well for an easier-to-administer shot version from the same scientists that’s in early testing in infants, children and adults.

The U.S. government research was published Monday in the New England Journal of Medicine and presented at a medical meeting in Seattle. 

The antibody works by breaking the life cycle of the parasite, which is spread through mosquito bites. It targets immature parasites before they enter the liver where they can mature and multiply. It was developed from an antibody taken from a volunteer who received a malaria vaccine. 

The research involved 330 adults in Mali who got either one of two different antibody doses or a dummy infusion. All were tested for malaria infection every two weeks for 24 weeks. Anyone who got sick was treated. 

Infections were detected by blood test in 20 people who got the higher dose, 39 people who got the lower dose and 86 who got the placebo. 

The higher dose was 88% effective, compared to the placebo. The lower dose was 75% effective. 

Protection might last during the several months of a malaria season. The idea is to someday use it alongside other malaria prevention methods such as malaria pills, mosquito nets and vaccines. Cost is uncertain, but one estimate suggests lab-made antibodies could be given for as little as $5 per child per malaria season. 

Lab-made antibodies are used to treat cancer, autoimmune diseases and COVID-19, said Dr. Johanna Daily of Albert Einstein College of Medicine in New York, who was not involved in the study. 

“The good news is now we have another, immune-based therapy to try to control malaria,” Daily said. 

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Australia Bans More Single-Use Plastics

On Tuesday, Nov. 1, Australia’s most populous state is banning a range of single-use plastic, including straws, cutlery and bowls.

Polystyrene foam food containers are also banned under the new rules in New South Wales, along with some face, body and hair products that contain plastic micro beads.   

Businesses that breach the regulations could face fines of tens of thousands of dollars.  

Minister for Environment and Heritage James Griffin said in a statement in September that the ban was just the start of a “massive shift away from single-use plastic.”  

He has predicted the ban would stop 2.7 billion items of plastic ending up as litter over the next 20 years. 

The laws in New South Wales are part of a nationwide push to curb waste. State authorities in Queensland and Victoria will bring in similar bans next year.  

Environmental campaigners have welcomed the laws but insist much more needs to be done. Australia currently recycles 16% of its plastic packaging, below the national target of 70%.   

Shane Cucow of the Australian Marine Conservation Society told VOA that recycling needs to be improved, because “Every wrap, pack and snack at a supermarket these days is covered in plastic.”

He added that, “We can get rid of some of those single-use plastics that are highly littered and regularly ending up in our oceans like cups and straws and take-away containers and plastic bags, and that is really important, but at the same time there is just so much plastic packaging on everything that is not able to be recycled properly and so it has got nowhere to go except being buried in landfill or washing out into our oceans.”

In June, New South Wales also banned lightweight plastic bags.

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China’s 3rd and Final Space Station Component Docks

China’s third and final module docked with its permanent space station Tuesday to further a decadeslong effort to maintain a constant crewed presence in orbit, as its competition with the United States grows increasingly fierce.

The Mengtian module arrived at the Tiangong station early Tuesday morning, state broadcaster CCTV said, citing the China Manned Space Agency.

Mengtian was blasted into space on Monday afternoon from the Wenchang Satellite Launch Center on the southern island province of Hainan. It was expected to take about 13 hours to complete the flight and docking mission.

A large crowd of amateur photographers, space enthusiasts and others watched the lift-off from an adjoining beach.

Many waved Chinese flags and wore T-shirts emblazoned with the characters for China, reflecting the deep national pride invested in the space program and the technological progress it represents.

“The space program is a symbol of a major country and a boost to the modernization of China’s national defense,” said Ni Lexiong, a professor at Shanghai University of political science and law, underscoring the program’s close military links.

“It is also a boost to the confidence of the Chinese people, igniting patriotism and positive energy,” Ni said.

Mengtian, or “Celestial Dream,” joins Wentian as the second laboratory module for the station, collectively known as Tiangong, or “Celestial Palace.” Both are connected to the Tianhe core module where the crew lives and works.

Like its predecessors, Mengtian was launched aboard a Long March-5B carrier rocket, a member of China’s most powerful family of launch vehicles.

Tiangong is currently populated by a crew of three astronauts — two males and one female, according to the China Manned Space Agency.

Chen Dong, Cai Xuzhe and Liu Yang arrived in early June for a six-month stay on board, during which they will complete the station’s assembly, conduct space walks and carry out additional experiments.

Following Mengtian’s arrival, an additional uncrewed Tianzhou cargo craft is due to dock with the station next month, with another crewed mission scheduled for December, at which time crews may overlap, as Tiangong has sufficient room to accommodate six astronauts.

Mengtian weighs in at about 23 tons, is 17.9 meters long and has a diameter of 4.2 meters. It will provide space for science experiments in zero gravity, an airlock for exposure to the vacuum of space and a small robotic arm to support extravehicular payloads.

The already orbiting 23-ton Wentian, or “Quest for the Heavens” laboratory is designed for science and biology experiments and is heavier than any other single-module spacecraft currently in space.

Next year, China plans to launch the Xuntian space telescope, which, while not a part of Tiangong, will orbit in sequence with the station and can dock occasionally with it for maintenance.

No other future additions to the space station have been publicly announced.

In all, the station will have about 110 cubic meters of pressurized interior space, including the 32 cubic meters added by Mengtian.

China’s crewed space program is officially three decades old this year, with the Mengtian launch being its 25th mission. But it truly got underway in 2003, when China became only the third country after the U.S. and Russia to put a human into space using its own resources.

The program is run by the ruling Communist Party’s military wing, the People’s Liberation Army, and has proceeded methodically and almost entirely without outside support. The U.S. excluded China from the International Space Station because of its program’s military ties.

Despite that, China is collaborating with the European Space Agency on experiments aboard Mengtian and is cooperating with France, Germany, Italy, Russia, Pakistan and the U.N. Office for Outer Space Affairs (UNOOSA) on a range of projects from aerospace medicine to microgravity physics, according to the Chinese Academy of Sciences.

Prior to launching the Tianhe module, China’s Manned Space Program launched a pair of single-module stations that it crewed briefly as test platforms.

The permanent Chinese station will weigh about 66 tons — a fraction of the size of the International Space Station, which launched its first module in 1998 and weighs around 465 tons.

With a lifespan of 10 to 15 years, Tiangong could one day find itself the only space station still running, if the International Space Station adheres to its 30-year operating plan.

China has also chalked up successes with uncrewed missions, and its lunar exploration program generated media buzz last year when its Yutu 2 rover sent back pictures of what was described by some as a “mystery hut” but was most likely only a rock. The rover is the first to be placed on the little-explored far side of the moon.

China’s Chang’e 5 probe returned lunar rocks to Earth for the first time since the 1970s in December 2000, and another Chinese rover is searching for evidence of life on Mars. Officials are also considering a crewed mission to the moon.

The program has also drawn controversy. In October 2021, China’s Foreign Ministry brushed off a report that China had tested a hypersonic missile two months earlier, saying it had merely tested whether a new spacecraft could be reused.

China is also reportedly developing a highly secret space plane.

China’s space program has proceeded cautiously and largely gone off without a hitch.

Complaints, however, have been leveled against China for allowing rocket stages to fall to Earth uncontrolled twice before. NASA accused Beijing last year of “failing to meet responsible standards regarding their space debris” after parts of a Chinese rocket landed in the Indian Ocean.

China’s increasing space capabilities was also featured in the latest Pentagon defense strategy released Thursday.

“In addition to expanding its conventional forces, the PLA is rapidly advancing and integrating its space, counterspace, cyber, electronic and informational warfare capabilities to support its holistic approach to joint warfare,” the strategy said.

The U.S. and China are at odds on a range of issues, especially the self-governing island of Taiwan that Beijing threatens to annex with force. China responded to a September visit to Taiwan by U.S. House Speaker Nancy Pelosi by firing missiles over the island, holding wargames and staging a simulated blockade.

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Satellites Shed Light on Dictators’ Lies About Economic Growth

Several dictators are significantly overstating economic growth, according to research which looks at satellite images of countries at night. As Henry Ridgwell reports, economists have long questioned the reliability of data from autocratic regimes – including China.

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