Day: July 23, 2024

Geneva — A senior World Health Organization official expressed alarm Tuesday at the high risk of polio spreading within the Gaza Strip because of dire sanitary conditions in the war-wracked enclave, and that the paralytic disease it causes could spill across borders without prompt action to stem the outbreak.

“I am, like, super worried,” Dr. Avadil Saparbekov, team lead for health emergencies at the WHO in the occupied Palestinian territory, told journalists from Jerusalem. “I am extremely worried about an outbreak happening in Gaza … and that it may spill over internationally at a very high point.” 

Saparbekov, who recently returned from a weeklong visit to Gaza, confirmed that “circulating vaccine-derived poliovirus type 2” has been identified in samples of Gazan sewage assessed by researchers and that an epidemiological probe “to identify the potential source of this importation” is underway.

“Based on the results of the assessment, WHO and the GPEI (Global Polio Eradication Initiative) partners will consolidate a set of recommendations, including the need for a mass vaccination campaign,” he said.

On July 16, the Global Polio Laboratory Network isolated the virus in six environmental surveillance samples collected from sewage on June 23 in Khan Younis and Deir al Balah in Gaza.

The WHO reports that further genomic sequencing of the samples by the U.S. Centers for Disease Control and Prevention indicates that they are related to environmental samples that were circulating in Egypt during the second half of last year.

“It is important to note that poliovirus has been isolated from environmental samples only at this time; no associated paralytic cases have been detected,” Saparbekov stressed.

Circulating vaccine-derived poliovirus is transmitted from person to person mainly through the fecal-oral route. It can invade a person’s nervous system and cause paralysis and death.

“We have not yet collected the human samples to identify any viruses because of the lack of equipment to collect those and lack of capacity to test those samples,” Saparbekov said, noting that WHO and UNICEF teams entering Gaza on Thursday will bring up to 50 sample collection kits “so we will be able to collect human samples, stool samples from humans.”

The samples, he said, will be sent to a lab in Jordan to confirm any cases of infection.

“Until that is done, I cannot say that there are any humans that are affected with this circulating vaccine-derived poliovirus,” he said.

The WHO said that wild poliovirus was eliminated more than 25 years ago in the Palestinian territories. Before the start of the war in Gaza, following a vicious attack on Israel by Hamas militants on October 7, the U.N. health agency says 89% of the population was vaccinated against polio, primarily conducted through routine immunization.

Last Sunday, Israel’s military said it would offer polio vaccinations to soldiers serving in Gaza to protect against the paralytic disease.

Saparbekov said the WHO will be reaching out to COGAT, the Israeli authority responsible for the coordination of government activities in the Palestinian territories, “to see how they can facilitate” the response to the outbreak. One way to do that, he added, is to have vaccines available for Gazans in case “there is a decision to conduct a mass campaign.”

“We have so far received assurances that this will be done,” he said.

The WHO official expressed hope that the epidemiological investigation and risk assessment would be completed by the end of the week, such that his team “will have a joint recommendation from the GPEI network about what to do with this particular outbreak” by Sunday.

In the meantime, he said, aid workers are doing their best to inform the population as to health measures they must take to prevent a polio outbreak.

“Given the water and sanitation limitations in Gaza, it will be very difficult for the population to follow the advice to wash their hands, to drink safe water,” he said.

“Unfortunately, the majority that live in shelters with one toilet for 600 people and maybe 1.5 liters of water per person, will definitely not be able to follow the recommendations that we are providing,” he said.

While reiterating concerns about polio spreading in the Palestinian enclave, WHO health emergency chief Saparbekov said he also is very worried about the possible outbreak of other communicable diseases.

“We had Hepatitis A confirmed last year and now we may have a polio outbreak,” he said. “So, with the crippled health system, lack of water and sanitation, as well as lack of access of the population to health services, specifically primary health services, this is going to be a very bad situation that will happen in Gaza.

“We may have more people dying from communicable diseases than from injuries and related conditions,” he warned.
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Some people who have lost the ability to speak can still move their vocal cords. California researchers are working to transform those muscle movements into audible speech. Genia Dulot reports from Los Angeles in this week’s edition of LogOn.
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United Nations — Nearly 40 million people were living with the HIV virus that causes AIDS last year, over 9 million weren’t getting any treatment, and the result was that every minute someone died of AIDS-related causes, the U.N. said in a new report launched Monday.

While advances are being made to end the global AIDS pandemic, the report said progress has slowed, funding is shrinking, and new infections are rising in three regions: the Middle East and North Africa, Eastern Europe and Central Asia, and Latin America.

In 2023, around 630,000 people died from AIDS-related illnesses, a significant decline from the 2.1 million deaths in 2004. But the latest figure is more than double the target for 2025 of fewer than 250,000 deaths, according to the report by UNAIDS, the U.N. agency leading the global effort to end the pandemic.

Gender inequality is exacerbating the risks for girls and women, the report said, citing the extraordinarily high incidence of HIV among adolescents and young women in parts of Africa.

The proportion of new infections globally among marginalized communities that face stigma and discrimination – sex workers, men who have sex with men, and people who inject drugs also increased to 55% in 2023 from 45% in 2010, it said.

UNAIDS Executive Director Winnie Byanyima said: “World leaders pledged to end the AIDS pandemic as a public health threat by 2030, and they can uphold their promise, but only if they ensure that the HIV response has the resources it needs, and that the human rights of everyone are protected.”

As part of that pledge, leaders vowed to reduce annual new HIV infections to below 370,000 by 2025, but the report said in 2023 new infections were more than three times higher at 1.3 million.

Last year, among the 39.9 million people globally living with HIV, 86% knew they were infected, 77% were accessing treatment, and for 72% the virus was suppressed, the report said

Cesar Nunez, director of the UNAIDS New York office, told a news conference there has been progress in HIV treatments — injections that can stay in the body for six months, but the two doses cost $40,000 yearly, out of reach for all but the richest people with the virus.

He said UNAIDS has been asking the manufacturer to make it available at lower cost to low and middle-income countries.

Nunez said there have also been seven cases where people with HIV who were treated for leukemia emerged with no sign of the HIV virus in their system.

He said injections and the seven cases will be discussed at the 25th International AIDS Conference which began Monday in Munich.

At present, he said, daily treatment with pills costs about $75 per person per year. It has allowed many countries to increase the number of people with HIV to receive treatment.

Nunez said UNAIDS will continue advocating for a vaccine to prevent AIDS.
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