Month: November 2023

The World Health Organization said it has confirmed sexual transmission of mpox in the Democratic Republic of Congo for the first time as the country experiences its biggest outbreak, a worrying development that African scientists warn could make it more difficult to stop the disease.

In a statement issued late Thursday, the U.N. health agency said a resident of Belgium traveled to Congo in March and tested positive for mpox, or monkeypox, shortly afterward. The WHO said the individual “identified himself as a man who has sexual relations with other men” and that he had gone to several underground clubs for gay and bisexual men.

Among his sexual contacts, five later tested positive for mpox, the WHO said.

“This is the first definitive proof of sexual transmission of monkeypox in Africa,” said Oyewale Tomori, a Nigerian virologist who sits on several WHO advisory groups. “The idea that this kind of transmission could not be happening here has now been debunked.”

Mpox has been endemic in parts of central and west Africa for decades, where it mostly jumped into humans from infected rodents and caused limited outbreaks. Last year, epidemics triggered mainly by sex among gay and bisexual men in Europe hit more than 100 countries. The WHO declared the outbreak as a global emergency, and it has caused about 91,000 cases to date.

The WHO noted there were dozens of discrete clubs in Congo where men have sex with other men, including members who travel to other parts of Africa and Europe. The agency described the recent mpox outbreak as unusual and said it highlighted the risk the disease could spread widely among sexual networks.

The WHO added that the mpox outbreak this year in Congo, which has infected more than 12,500 people and killed about 580, also marked the first time the disease has been identified in the capital, Kinshasa, and in the conflict-ridden province of South Kivu. Those figures are roughly double the mpox toll in 2020, making it Congo’s biggest outbreak, the WHO said.

Virologist Tomori said that even those figures were likely an underestimate and had implications for the rest of Africa, given the continent’s often patchy disease surveillance.

“What’s happening in Congo is probably happening in other parts of Africa,” he said. “Sexual transmission of monkeypox is likely established here, but [gay] communities are hiding it because of the draconian [anti-LGBTQ+] laws in several countries.”

He warned that driving people at risk for the virus underground would make the disease harder to curb.

The mpox virus causes fever, chills, rash and lesions on the face or genitals. Most people recover within several weeks without requiring hospitalization.

The WHO said the risk of mpox spreading to other countries in Africa and globally “appears to be significant,” adding that there could be “potentially more severe consequences” than the worldwide epidemic last year.

Tomori lamented that while the mpox outbreaks in Europe and North America prompted mass immunization campaigns among affected populations, no such plans were being proposed for Africa.

“Despite the thousands of cases in Congo, no vaccines have arrived,” he said. Even after mpox epidemics subsided in the West, few shots or treatments were made available for Africa.

“We have been saying for years in Africa that monkeypox is a problem,” he said. “Now that sexual transmission has been confirmed here, this should be a signal to everyone to take it much more seriously.”
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South Africa, Colombia and other countries that lost out in the global race for coronavirus vaccines are taking a more combative approach toward drugmakers and pushing back on policies that deny cheap treatment to millions of people with tuberculosis and HIV.

Experts see it as a shift in how such countries deal with pharmaceutical behemoths and say it could trigger more efforts to make lifesaving medicines more widely available.

In the COVID-19 pandemic, rich countries bought most of the world’s vaccines early, leaving few shots for poor countries and creating a disparity the World Health Organization called “a catastrophic moral failure.”

Now, poorer countries are trying to become more self-reliant “because they’ve realized after COVID they can’t count on anyone else,” said Brook Baker, who studies treatment-access issues at Northeastern University.

One of the targets is a drug, bedaquiline, that is used for treating people with drug-resistant versions of tuberculosis. The pills are especially important for South Africa, where TB killed more than 50,000 people in 2021, making it the country’s leading cause of death.

In recent months, activists have protested efforts by Johnson & Johnson to protect its patent on the drug. In March, TB patients petitioned the Indian government, calling for cheaper generics; the government ultimately agreed Johnson & Johnson’s patent could be broken. Belarus and Ukraine then wrote to the company, also asking it to drop its patents, but with little response.

In July, Johnson & Johnson’s patent on the drug expired in South Africa, but the company had it extended until 2027, enraging activists who accused it of profiteering.

The South African government then began investigating the company’s pricing policies.

It had been paying about 5,400 rand ($282) per treatment course, more than twice as much as poor countries that got the drug via a global effort called the Stop TB partnership.

In September, about a week after South Africa’s probe began, Johnson & Johnson announced that it would drop its patent in more than 130 countries, allowing generic-makers to copy the drug.

“This addresses any misconception that access to our medicines is limited,” the company said.

Christophe Perrin, a tuberculosis expert at Doctors Without Borders, called Johnson & Johnson’s reversal “a big surprise” because aggressive patent protection was typically a “cornerstone” of pharmaceutical companies’ strategy.

Meanwhile, in Colombia, the government declared last month that it would issue a compulsory license for the HIV drug dolutegravir without permission from the drug’s patent-holder, Viiv Health care. The decision came after more than 120 groups asked the Colombian government to expand access to the World Health Organization-recommended drug.

“This is Colombia taking the reins after the extreme inequity of COVID and challenging a major pharmaceutical to ensure affordable AIDS treatment for its people,” said Peter Maybarduk of the Washington advocacy group Public Citizen. He noted that Brazilian activists are pushing their government to make a similar move.

Still, some experts said much more needs to change before poorer countries can produce their own medicines and vaccines.

When the coronavirus pandemic hit, Africa produced fewer than 1% of all vaccines made globally but used more than half of the world’s supply, according to Petro Terblanche, managing director of Afrigen Biologics. The company is part of a WHO-backed effort to produce a COVID vaccine using the same mRNA technology as those made by Pfizer and Moderna.

Terblanche estimated about 14 million people died of AIDS in Africa from the late 1990s into the 2000s, when countries couldn’t get the necessary medicines.

Back then, President Nelson Mandela’s government in South Africa eventually suspended patents to allow wider access to AIDS drugs. That prompted more than 30 drugmakers to take it to court in 1998, in a case dubbed “Mandela vs. Big Pharma.”

Doctors Without Borders described the episode as “a public relations disaster” for the drug companies, which dropped the lawsuit in 2001.

Terblanche said that Africa’s experience during the HIV epidemic has proven instructive.

“It’s not acceptable for a listed company to hold intellectual property that stands in the way of saving lives and, so, we will see more countries fighting back,” she said.

Challenging pharmaceutical companies is just one piece to ensuring Africa has equal access to treatments and vaccines, Terblanche said. More-robust health systems are critical.

“If we can’t get [vaccines and medicines] to the people who need them, they aren’t useful,” she said.

Yet some experts pointed out that South Africa’s own intellectual property laws still haven’t been changed sufficiently and make it too easy for pharmaceutical companies to acquire patents and extend their monopolies.

While many other developing countries allow legal challenges to a patent or a patent extension, South Africa has no clear law that allows it to do that, said Lynette Keneilwe Mabote-Eyde, a health care activist who consults for the nonprofit Treatment Action Group.

The South African department of health didn’t respond to a request for comment regarding drug procurement and patents.

In its annual report on tuberculosis released earlier this month, the World Health Organization said there were more than 10 million people sickened by the disease last year and 1.3 million deaths. After COVID-19, tuberculosis is the world’s deadliest infectious disease, and it is now the top killer of people with HIV.
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Chinese officials say they did not detect any “unusual or novel diseases” in the country, the World Health Organization said Thursday, following an official request by the U.N. health agency for information about a potentially worrying spike in respiratory illnesses and clusters of pneumonia in children. 

WHO cited unspecified media reports and a global infectious-disease monitoring service as reporting clusters of undiagnosed pneumonia in children in northern China and formally requested more details from China earlier this week. 

Outside scientists said the situation warranted close monitoring, but they were not convinced that the recent spike in respiratory illnesses in China signaled the start of a new global outbreak. 

The emergence of new flu strains or other viruses capable of triggering pandemics typically starts with undiagnosed clusters of respiratory illness. Both SARS and COVID-19 were first reported as unusual types of pneumonia. 

WHO noted that authorities at China’s National Health Commission on November 13 reported an increase in respiratory diseases, which they said was the result of the lifting of COVID-19 lockdown restrictions. Other countries also saw a jump in respiratory diseases such as respiratory syncytial virus, or RSV, when pandemic restrictions ended. 

WHO said that about a week later, media reported clusters of undiagnosed pneumonia in children in northern China. 

The U.N. agency said it held a teleconference with Chinese health officials on Thursday, during which the data it requested were provided. Those showed an increase in hospital admissions of children due to diseases including bacterial infection, RSV, influenza and common cold viruses since October. 

“No changes in the disease presentation were reported by the Chinese health authorities,” WHO said. It added that Chinese officials said the spike in patients had not overloaded the country’s hospitals. 

New disease doubted

Dr. Paul Hunter, a professor of medicine at Britain’s University of East Anglia, doubted the wave of infections was sparked by a new disease. 

“If it was [a new disease], I would expect to see many more infections in adults,” he said in a statement. “The few infections reported in adults suggest existing immunity from a prior exposure.” 

Francois Balloux of University College London said China was probably experiencing a significant wave of childhood infections since this was the first winter since lockdown restrictions were lifted, which likely reduced children’s immunity to common bugs. 

WHO said that northern China has reported a jump in influenzalike illnesses since mid-October compared with the previous three years. It is rare for the U.N. health agency to publicly ask for more detailed information from countries, as such requests are typically made internally. WHO said it requested further data from China via an international legal mechanism. 

According to internal accounts in China, the outbreaks have swamped some hospitals in northern China, including in Beijing, and health authorities have asked the public to take children with less severe symptoms to clinics and other facilities. 

The average number of patients in the internal medicine department at Beijing Children’s Hospital topped 7,000 per day, exceeding the hospital’s capacity, state-owned China National Radio said in an online article earlier this week. 

China’s National Health Commission, in a written Q&A posted online by the official Xinhua News Agency, suggested Thursday that children with mild symptoms “first visit primary health care institutions or pediatrics departments of general hospitals” because large hospitals are crowded and have long waiting times. 

WHO said that there was too little information at the moment to properly assess the risk of these reported cases of respiratory illness in children. The agency has previously been stymied by a lack of cooperation from countries when new viruses have emerged, particularly in China. 

After SARS broke out in southern China in 2002, Beijing officials told doctors to hide patients, with some being driven around in ambulances while WHO scientists were visiting the country. That prompted WHO to threaten to close its office in China. 

Nearly two decades later, China stalled on sharing critical details about the coronavirus with the U.N. health agency after the new virus emerged in late 2019. WHO publicly applauded China’s commitment to stopping the virus — weeks before it started causing explosive epidemics worldwide. 

“While WHO seeks this additional information, we recommend that people in China follow measures to reduce the risk of respiratory illness,” the agency said, advising people to get vaccinated, isolate if they are feeling ill, wear masks if necessary and get medical care as needed. 
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Authorities in several West African countries are trying to manage their huge diphtheria outbreaks, including in Nigeria where a top health official said Thursday that millions are being vaccinated to cover wide gaps in immunity against the disease.

At least 573 people out of the 11,640 diagnosed with the disease in Nigeria have died since the current outbreak started in December 2022, though officials estimate the toll — now on the decline because of treatment efforts — could be much higher across states unable to detect many cases.

In Niger, 37 people had died out of the 865 cases as of October, while Guinea has reported 58 deaths out of 497 since its outbreak started in June.

“As far as the history that I am aware of, this is the largest outbreak that we have had,” Ifedayo Adetifa, head of the Nigeria Centre for Disease Control, told The Associated Press.

The highly contagious bacterial infection has been reported in 20 of Nigeria’s 36 states so far.

A major driver of the high rate of infection in the region has been a historically wide vaccination gap, the French medical organization Doctors Without Borders, or MSF, said in a statement on Tuesday.

In Nigeria, only 42% of children under 15 years old are fully protected from diphtheria, according to a government survey, while Guinea has a 47% immunization rate — both far below the 80-85% rate recommended by the World Health Organization to maintain community protection.

The fate of the affected countries is worsened by the global shortages of the diphtheria vaccine as demand has increased to respond to outbreaks, MSF said.

“We’re not seeing vaccination happen, not at the scale that is needed,” said Dr. Dagemlidet Tesfaye Worku, emergency medical program manager for MSF in Abidjan, Ivory Coast. “What is needed is a truly massive scale-up of vaccination, as soon as possible.”

The Nigerian government is ramping up vaccination for targeted populations while assisting states to boost their capacity to detect and manage cases, said Adetifa, the Nigeria CDC head.

But several states continue to struggle, including Kano, which accounts for more than 75% of cases in Nigeria but has only two diphtheria treatment centers, according to Abubakar Labaran Yusuf, the state’s top health official.

“Once people have to travel or move significant distances to access treatment, that becomes a challenge,” Adetifa said.
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A 14-year-old Ethiopian-born American in the U.S. state of Virginia has won the 3M Young Scientist Challenge, an annual science competition for U.S. students in grades five through eight. VOA’s Eden Geremew recently spoke with the winner in Fairfax County, Virginia, in this report narrated by Salem Solomon. Camera: Karina Choudhury
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For most of her life, Claudia Stearns dreaded Thanksgiving. As a person who struggled with obesity since childhood, Stearns hated the annual turmoil of obsessing about what she ate — and the guilt of overindulging on a holiday built around food. 

Now, after losing nearly 100 pounds using medications including Wegovy, a powerful new anti-obesity drug, Stearns says the “food noise” in her head has gone very, very quiet. 

“Last year, it felt so lovely to just be able to enjoy my meal, to focus on being with friends and family, to focus on the joy of the day,” says Stearns, 65, of Somerville, Massachusetts. “That was a whole new experience.” 

As millions of Americans struggling with obesity gain access to a new generation of weight-loss drugs, Stearns’ experience is becoming more common — and more noticeable at the times of year when cooking, eating and a sense of abundance can define and heighten gatherings of loved ones and friends. Medical experts and consumers say the drugs are shifting not only what users eat, but also the way they view food.

For some, it means greater mental control over their meals. Others say it saps the enjoyment from social situations, including traditionally food-centric holidays like Thanksgiving, Passover and Christmas.

“It’s something that really changes a lot of things in their life,” says Dr. Daniel Bessesen, chief of endocrinology at Denver Health, who treats patients with obesity. “They go from food being a central focus to it’s just not.”

Undermining the festivities?

The new obesity drugs, originally designed to treat diabetes, include semaglutide, used in Ozempic and Wegovy, and tirzepatide, used in Mounjaro and recently approved as Zepbound. Now aimed at weight loss, too, the drugs delivered as weekly injections work far differently than any diet. They mimic powerful hormones that kick in after people eat to regulate appetite and the feeling of fullness communicated between the gut and the brain. Users can lose as much as 15% to 25% of their body weight, studies show. 

“That’s how it works — it reduces the rewarding aspects of food,” explains Dr. Michael Schwartz, an expert in metabolism, diabetes and obesity at the University of Washington in Seattle. 

For Stearns, who started treatment in 2020, using the weight-loss medications means she can take a few bites of her favorite Thanksgiving pies — and then stop. “I would not feel full,” she says, “but I would feel satisfied.” 

Yet such a shift can have broader implications, both religious and cultural, because it alters the experience of festive and religious holidays that are often built around interactions with food — and lots of it.

“I’m Italian. For us, it’s like going to church, going to a table,” says Joe Sapone, 64, a retiree from Atlantic Highlands, New Jersey, who lost about 100 pounds with dieting and Mounjaro. He no longer needs what he called “the food orgy” of a holiday, but he acknowledges it was an adjustment.

“Part of succeeding at this is disconnecting a good time with what you eat,” he says.

Changes in enjoyment

Many users welcome what they say is greater control over what they eat, even during the emotionally charged holiday season. 

“I may be more selective of the items I put on my plate,” says Tara Rothenhoefer, 48, of Trinity, Florida. She lost more than 200 pounds after joining a clinical trial testing Mounjaro for weight loss in 2020. “I don’t care about the bread as much. I still eat what I enjoy.” 

But others on the drugs lose their appetites entirely or suffer side effects — nausea, vomiting, diarrhea — that undermine the pleasure of any food. 

“I’ve had a handful of patients over the years who were really miserable because they didn’t enjoy food in the same way,” says Dr. Katherine Saunders, an obesity expert at Weill Cornell Medicine and co-founder of Intellihealth, a clinical and software company that focuses on obesity treatment. 

But, she added, most people who have turned to weight-loss medications have spent years struggling with the physical and mental burdens of chronic obesity and are relieved to discover a decreased desire for food — and grateful to shed pounds. 

When people stop taking the drugs, their appetites return and they regain weight, often faster than they lost it, studies show. One early analysis found that two-thirds of patients who started taking weight-loss drugs were no longer using them a year later. 

Part of that may be due to the high cost and ongoing supply shortages. But the larger question of what it means to alter a basic human drive like appetite needs to be considered as well, says Dr. Jens Juul Holst of the University of Copenhagen. He is one of the researchers who first identified the gut hormone GLP-1, or glucagon-like peptide 1, which eventually led to the new class of obesity drugs. 

Speaking at an international diabetes conference this fall, Holst offered a philosophical critique of the new medications’ real-world impact. 

“Why is it that you’ve lost weight? That’s because you’ve lost your appetite. That’s because you’ve lost the pleasure of eating and the reward of having a beautiful meal,” Holst told his colleagues. “And how long can you stand that? That is the real, real question.” 
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Cindy Dyer, the U.S. ambassador-at-large for monitoring and combating trafficking, is planning to push Cambodia’s new government to ramp up its efforts to crack down on cyberscam operations that trap many trafficking victims in slavelike conditions.

A recently completed visit to Phnom Penh by Dyer “will serve as an opportunity for information sharing and coordination on anti-trafficking efforts,” the State Department said last week in a release.

Dyer met with a range of officials “with the objective of building a relationship with the new government for future coordination and advocating for progress in the most critical areas, including increased investigations and prosecutions of cyberscam operations,” said the November 15 release.

Cambodia’s role as host of cybercriminals has been in an international spotlight. The U.N. High Commissioner for Human Rights (UNHCHR) released a report this summer estimating that the industry has victimized 100,000 people in Cambodia.

Lured by promise of jobs

Operators of these scamming networks recruit unwitting workers from across Asia, often with the promise of well-paying tech jobs, and then force them to attempt to scam victims online while living in slavelike conditions, according to the report.

Countries including Indonesia, Taiwan and China have urged countries like Cambodia and Laos to crack down on the industry, while warning their own citizens of the dangers in traveling to these countries, according to the UNHCHR report.

The U.S. State Department’s annual report on global human trafficking, released in June, placed Cambodia in Tier 3, meaning the government has made insufficient efforts to address human trafficking and does not meet the minimum standards.

During her two-day visit to Cambodia that began November 15, Dyer met with officials from the ministries of justice, labor and social affairs, as well as representatives of the National Police and the National Committee for Counter Trafficking (NCCT) within the Ministry of Interior, according to an email from the U.S. Embassy in Phnom Penh. Dyer also held discussions with civil society groups working on combating human trafficking.

The discussions focused “on Cambodia’s efforts to protect trafficking victims, including providing protection assistance services for victims of trafficking and vulnerable migrants, capacity building for service providers and government officials to improve victim identification and referral, and addressing emerging trends in forced criminality,” the State Department release said.

More training urged

Am Sam Ath, operations director at the Cambodian rights group Licadho, told VOA Khmer that Dyer’s visit highlighted the need for Cambodia to tackle human trafficking and online scams.

“We see that the United States … ranks Cambodia third in the blacklist of human trafficking. It also has a lot of impact on our country, and if Cambodia does not make an effort further in the prevention of human trafficking or online scams, the ranking cannot be improved,” he said by telephone from the group’s Phnom Penh office.

He called on the Cambodian government to strengthen the capacity of officials and authorities to crack down on online crime.

“This crime problem is technologically modern, so the authorities involved in it have to get more training to keep up with the situation, as well as the timing of the crime,” Am Sam Ath added.

National Police spokesperson Chhay Kim Khoeun and Justice Ministry spokesperson Chin Malin declined to comment on Dyer’s visit, referring questions to Chou Bun Eng, permanent deputy chairman of the National Committee for Counter Trafficking. VOA Khmer called Chou Bun Eng, but she did not respond to a request for comment.

U.S. Embassy spokesperson Katherine Diop told VOA Khmer that Dyer’s visit to Cambodia was part of a U.S. effort across the world to encourage governments to take responsibility for preventing human trafficking and protecting victims.

“The United States stands with the Cambodian people to identify, support and seek justice for human trafficking victims,” she wrote in an email.

The UNHCHR report released in late August said the online scams were occurring in five countries in Southeast Asia: Cambodia, Thailand, Laos, Myanmar and the Philippines.

“People who have been trafficked into online forced criminality face threats to their right to life, liberty and security of the person,” said the U.N. report. “They are subject to torture and cruel, inhuman and degrading treatment or punishment, arbitrary detention, sexual violence, forced labor and other forms of labor exploitation as well as a range of other human rights violations and abuses.”

Cambodia first acknowledged the issue last year when Interior Minister Sar Kheng said in August that officials were being deployed across the country to check hotels, casinos and other establishments for potential trafficking victims.

The government has since announced sporadic operations to free victims and arrest traffickers. However, experts recently told VOA Khmer that these efforts have not noticeably curbed the illegal operations or caught ringleaders of the trafficking networks.
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Rising sea levels, extreme weather and rising temperatures are threatening coastal communities in South Africa. For VOA, Derick Mazarura has the story from Eastern Cape, South Africa. Camera — Buhle Ndamase and Norah Chisa.
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The ousted leader of ChatGPT-maker OpenAI is returning to the company that fired him late last week, culminating a days-long power struggle that shocked the tech industry and brought attention to the conflicts around how to safely build artificial intelligence.

San Francisco-based OpenAI said in a statement late Tuesday, “We have reached an agreement in principle for Sam Altman to return to OpenAI as CEO with a new initial board.”

The board, which replaces the one that fired Altman on Friday, will be led by former Salesforce co-CEO Bret Taylor, who also chaired Twitter’s board before its takeover by Elon Musk last year. The other members will be former U.S. Treasury Secretary Larry Summers and Quora CEO Adam D’Angelo.

OpenAI’s previous board of directors, which included D’Angelo, had refused to give specific reasons for why it fired Altman, leading to a weekend of internal conflict at the company and growing outside pressure from the startup’s investors.

The chaos also accentuated the differences between Altman — who’s become the face of generative AI’s rapid commercialization since ChatGPT’s arrival a year ago — and members of the company’s board who have expressed deep reservations about the safety risks posed by AI as it becomes more advanced.

Microsoft, which has invested billions of dollars in OpenAI and has rights to its current technology, quickly moved to hire Altman on Monday, as well as another co-founder and former president, Greg Brockman, who had quit in protest after Altman’s removal.

That emboldened a threatened exodus of nearly all of the startup’s 770 employees who signed a letter calling for the board’s resignation and Altman’s return.

One of the four board members who participated in Altman’s ouster, OpenAI co-founder and chief scientist Ilya Sutskever, later expressed regret and joined the call for the board’s resignation.

Microsoft in recent days had pledged to welcome all employees who wanted to follow Altman and Brockman to a new AI research unit at the software giant. Microsoft CEO Satya Nadella also made clear in a series of interviews Monday that he was still open to the possibility of Altman returning to OpenAI, so long as the startup’s governance problems are solved.

“We are encouraged by the changes to the OpenAI board,” Nadella posted on X late Tuesday. “We believe this is a first essential step on a path to more stable, well-informed, and effective governance.”

In his own post, Altman said that “with the new board and (with) Satya’s support, I’m looking forward to returning to OpenAI, and building on our strong partnership with (Microsoft).”

Co-founded by Altman as a nonprofit with a mission to safely build so-called artificial general intelligence that outperforms humans and benefits humanity, OpenAI later became a for-profit business but one still run by its nonprofit board of directors. It’s not clear yet if the board’s structure will change with its newly appointed members.

“We are collaborating to figure out the details,” OpenAI posted on X. “Thank you so much for your patience through this.”

Nadella said Brockman, who was OpenAI’s board chairman until Altman’s firing, will also have a key role to play in ensuring the group “continues to thrive and build on its mission.”

Hours earlier, Brockman returned to social media as if it were business as usual, touting a feature called ChatGPT Voice that was rolling out to users.

“Give it a try — totally changes the ChatGPT experience,” Brockman wrote, flagging a post from OpenAI’s main X account that featured a demonstration of the technology and playfully winking at recent turmoil.

“It’s been a long night for the team and we’re hungry. How many 16-inch pizzas should I order for 778 people?” the person asks, using the number of people who work at OpenAI. ChatGPT’s synthetic voice responded by recommending around 195 pizzas, ensuring everyone gets three slices.

As for OpenAI’s short-lived interim CEO Emmett Shear, the second interim CEO in the days since Altman’s ouster, he posted on X that he was “deeply pleased by this result, after ~72 very intense hours of work.”

“Coming into OpenAI, I wasn’t sure what the right path would be,” wrote Shear, the former head of Twitch. “This was the pathway that maximized safety alongside doing right by all stakeholders involved. I’m glad to have been a part of the solution.”
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The U.S. government dealt a massive blow to Binance, the world’s largest cryptocurrency exchange, which agreed to pay a roughly $4 billion settlement Tuesday as its founder and CEO Changpeng Zhao pleaded guilty to a felony related to his failure to prevent money laundering on the platform. 

Zhao stepped down as the company’s chief executive, and Binance admitted to violations of the Bank Secrecy Act and apparent violations of sanctions programs, including its failure to implement reporting programs for suspicious transactions. 

“Using new technology to break the law does not make you a disruptor, it makes you a criminal,” said U.S. Attorney General Merrick Garland, who called the settlement one of the largest corporate penalties in the nation’s history. 

As part of the settlement agreement, the U.S. Treasury said Binance will be subject to five years of monitoring and “significant compliance undertakings, including to ensure Binance’s complete exit from the United States.” Binance is a Cayman Islands limited liability company. 

The cryptocurrency industry has been marred by scandals and market meltdowns. 

Rival of FTX founder

Zhao was perhaps best known as the chief rival to Sam Bankman-Fried, the 31-year-old founder of FTX, which was the second-largest crypto exchange before it collapsed last November. Bankman-Fried was convicted earlier this month of fraud for stealing at least $10 billion from customers and investors. 

Zhao, meanwhile, pleaded guilty in a federal court in Seattle on Tuesday to one count of failure to maintain an effective anti-money-laundering program. 

Magistrate Judge Brian A. Tsuchida questioned Zhao to make sure he understood the plea agreement, saying at one point: “You knew you didn’t have controls in place.” 

“Yes, your honor,” he replied. 

Binance wrote in a statement that it made “misguided decisions” as it quickly grew to become the world’s biggest crypto exchange, and said the settlement acknowledges its “responsibility for historical, criminal compliance violations.” 

U.S. Treasury Secretary Janet Yellen said Binance processed transitions by illicit actors, “supporting activities from child sexual abuse to illegal narcotics, to terrorism, across more than 100,000 transactions.” 

Binance did not file a single suspicious activity report on those transactions, Yellen said, and the company allowed more than 1.5 million virtual currency trades that violated U.S. sanctions, including ones involving Hamas’ al-Qassam Brigades, al-Qaida and other criminals. 

The judge set Zhao’s sentencing for February 23, however it’s likely to be delayed. He faces a possible guideline sentence range of up to 18 months. 

One of his attorneys, Mark Bartlett, noted that Zhao had been aware of the investigation since December 2020, and surrendered willingly even though the United Arab Emirates — where Zhao lives — has no extradition treaty with the U.S. 

“He decided to come here and face the consequences,” Bartlett said. “He’s sitting here. He pled guilty.” 

Zhao, who is married and has young children in the UAE, promised he would return to the U.S. for sentencing if allowed to stay there in the meantime. 

“I want to take responsibility and close this chapter in my life,” Zhao said. “I want to come back. Otherwise I wouldn’t be here today.” 

Company sent investor assets to third party

Zhao previously faced allegations of diverting customer funds, concealing the fact that the company was commingling billions of dollars in investor assets and sending them to a third party that Zhao also owned. 

Over the summer, Binance was accused of operating as an unregistered securities exchange and violating a slew of U.S. securities laws in a lawsuit from regulators. That case was similar to practices uncovered after the collapse of FTX. 

Zhao and Bankman-Fried were originally friendly competitors in the industry, with Binance investing in FTX when Bankman-Fried launched the exchange in 2019. However, the relationship between the two deteriorated, culminating in Zhao announcing he was selling all of his cryptocurrency investments in FTX in early November 2022. FTX filed for bankruptcy a week later. 

At this trial and in later public statements, Bankman-Fried tried cast blame on Binance and Zhao for allegedly orchestrating a run on the bank at FTX. 

A jury found Bankman-Fried guilty of wire fraud and several other charges. He is expected to be sentenced in March, where he could face decades in prison. 
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Growing up in Lahore — Pakistan’s cultural capital — fall used to be the perfect time for Mariam to enjoy outdoor activities after months of scorching summer heat. Now, she cannot imagine the same for her young daughters as Lahore’s air, ranked the most polluted globally, becomes unusually toxic in cooler months.

“You can just smell, sometimes you can taste it, and feel it as well,” said the mother of two describing what it is like to breathe the polluted air.

With an AQI reading of 345 early in the day, Lahore ranked second worst city in the world for air pollution on Tuesday, according to the Air Quality Index or AQI run by IQAir, a Swiss air purifier manufacturer.

An AQI above 151 is unhealthy, while above 301 the air is hazardous for breathing.

IQAir’s index ranked Lahore the most polluted city of 2022.

Smog emergency

The city, along with several other in Pakistan’s biggest province Punjab,is under a month-long smog emergency since early November.

Smog – a combination of smoke and fog – is a specific phenomenon that occurs when certain pollution particles mix with cold, moist air and hang close to the ground, reducing visibility.

In a bid to reduce traffic congestion and exposure to toxic air, the top court in Punjab on Monday ordered the closure of government-run educational institutions on Saturdays until the end of January 2024. The court also asked the provincial government to come up with a work-from-home plan for the private sector.

A year-long emergency

For a few weeks in fall, smoke in Punjab’s air increases as Pakistani and Indian farmers on both sides of the divided state burn agricultural residue to prepare fields for planting the next crop. Environmentalists, however, say the government is in denial about the extent of Pakistan’s pollution problem, which is primarily driven by low quality, high-Sulphur fuel.

“Air pollution has always been an issue in Pakistani cities, going back the better part of 15 odd years,” Ahmad Rafay Alam, a Lahore-based environmental lawyer told VOA. “We have a year-long regional air pollution emergency and we tend to think of it as a Lahore smog issue.”

According to the Air Quality Life Index developed by the Energy Policy Institute at the University of Chicago, 98.3 of Pakistanis breathe air that is below the country’s own national air quality standard.

In 2017 the provincial Environmental Protection Department came up with an 11-point policy, on court orders, focusing on controlling emissions from vehicles and factories.

The court was, however, dissatisfied and constituted a smog commission for detailed analysis and recommendations on improving air quality.

Speaking to VOA, Naseem-ur-Rehman Shah, secretary of the provincial Environment Commission claimed that 80% of factories were now monitoring their emissions while 70-percent of brick kilns had moved to an environmentally friendly design

Still, data paints a terrifying picture.

“Every figure is telling you that the air pollution in Lahore is about, on the lower end, like 30, 40 times higher than the WHO safe limits,” said Abid Omar, founder of Air Quality Pakistan Initiative, a network of volunteers who monitor air quality using IQAir monitors.

Omar is based in Karachi which routinely competes with Lahore and Delhi for the worst air quality in the world.

Monitoring

For the city of nearly 15 million people, Punjab’s environmental agency gathers data from only five air quality monitors in Lahore.

Omar’s Pakistan Air Quality Initiative has 50 monitors feeding into IQAir’s Air Quality Index.

Shah’s department does not use PAQI’s data over standardization concerns but it is planning to add several monitors of its own.

In 2019, the provincial environmental regulator was forced to revise its air quality standards after it emerged officials were underreporting pollution by using low standards.

Alam represented the complainants in taking the regulator to court.

Knee jerk reaction

With air quality declining dramatically this month, the provincial and city administration have ramped up crackdown on smoke-emitting factories, brick kilns, and vehicles.

Citing city administration, local media reported that more than 16,000 vehicles were ticketed and over $100,000 dollars in fines imposed since the beginning of the emergency.

Omar calls such administrative measures a knee jerk reaction lacking long-term impact.

“Because it’s very random and ad hoc implementation, it’s not going to be an effective policy,” Omar said.

Shah called such criticism unfair. “We are working to eliminate sources of pollution,” he said.

Policy shift

“What we need to do is improve the quality of our refineries, which don’t produce high quality fuels … you have to transition to renewable energies, which is expensive and time consuming,” said Alam, pointing to studies that show fuel and energy sector are among the primary polluters in the country.

In May this year, Pakistan’s Ministry of Climate Change introduced the National Clean Air Policy. It aims to reduce harmful emissions in the next 10 years by introducing interventions in transport, industry, agriculture, waste and household sectors.

Such an overhaul will take time, money, and political will.

For Mariam, who runs three air purifiers in her home, the only option at the moment is to keep her daughters indoors as much as possible.

“It actually feels like … you’re being deprived of something very basic … not being able to breathe in fresh air.”

According to the Air Quality Life Index at the University of Chicago, Pakistanis are losing 3.9 years of life expectancy because of breathing toxic air. In Lahore and the rest of Punjab, residents are on track to lose between 3.7 to 4.6 years of life expectancy.
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More people work from home in Colorado, while Mississippi has the lowest percentage of teleworkers
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In a move that may soon be replicated elsewhere, the Gila River Indian Community recently signed an agreement with the U.S. Army Corps of Engineers to put solar panels over a stretch of irrigation canal on its land south of Phoenix.

It will be the first project of its kind in the United States to break ground, according to the tribe’s press release.

“This was a historic moment here for the community but also for the region and across Indian Country,” said Gila River Indian Community Governor Stephen Roe Lewis in a video published on X, formerly known as Twitter.

The first phase, set to be completed in 2025, will cover 1,000 feet of canal and generate one megawatt of electricity that the tribe will use to irrigate crops, including feed for livestock, cotton and grains.

The idea is simple: install solar panels over canals in sunny, water-scarce regions where they reduce evaporation and make renewable electricity.

“We’re proud to be leaders in water conservation, and this project is going to do just that,” Lewis said, noting the significance of a Native, sovereign, tribal nation leading on the technology.

A study by the University of California, Merced estimated that 63 billion gallons of water could be saved annually by covering California’s 4,000 miles of canals. More than 100 climate advocacy groups are advocating for just that.

Researchers believe that much of the installed solar canopies would additionally generate a significant amount of electricity.

UC Merced wants to hone its initial estimate and should soon have the chance. Not far away in California’s Central Valley, the Turlock Irrigation District and partner Solar AquaGrid plan to construct 1.6 miles (2.6 kilometers) of solar canopies over its canals beginning this spring and researchers will study the benefits.

Neither the Gila River Indian Community nor the Turlock Irrigation District are the first to implement this technology globally. Indian engineering firm Sun Edison inaugurated the first solar-covered canal in 2012 on one of the largest irrigation projects in the world in Gujarat state. Despite ambitious plans to cover 11,800 miles (19,000 kilometers) of canals, only a handful of small projects ever went up, and the engineering firm filed for bankruptcy.

High capital costs, clunky design and maintenance challenges were obstacles for widespread adoption, experts say.

But severe, prolonged drought in the western U.S. has centered water as a key political issue, heightening interest in technologies like cloud seeding and solar-covered canals as water managers grasp at any solution that might buoy reserves, even ones that haven’t been widely tested, or tested at all.

Still, the project is an important indicator of the tribe’s commitment to water conservation, said Heather Tanana, a visiting law professor at the University of California, Irvine and citizen of the Navajo Nation. Tribes hold the most senior water rights on the Colorado River, though many are still settling those rights in court.

“There’s so much fear about the tribes asserting their rights and if they do so, it’ll pull from someone else’s rights,” she said. The tribe leaving water in Lake Mead and putting federal dollars toward projects like solar canopies is “a great example to show that fear is unwarranted.”

The federal government has made record funding available for water-saving projects, including a $233 million pact with the Gila River Indian Community to conserve about two feet of water in Lake Mead, the massive and severely depleted reservoir on the Colorado River. Phase one of the solar canal project will cost $6.7 million and the Bureau of Reclamation provided $517,000 for the design.
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Innovations in food production could alleviate hunger for millions of people, according to Britain, which hosted a global summit on food insecurity Monday, but critics say the focus on technology ignores the growing inequality of wealth.

The summit was a joint initiative between Britain, Somalia, the United Arab Emirates, the Children’s Investment Fund Foundation and the Bill and Melinda Gates Foundation, aimed at boosting food security through science and innovation.

Innovation hub

British Prime Minister Rishi Sunak said a renewed focus was needed to alleviate hunger.

“It can’t be right that today in 2023, almost 1 billion people across the world regularly do not have enough to eat, that millions face hunger and starvation, and over 45 million children under five are suffering acute malnutrition. In a world of abundance, no one should die from lack of food and no parent should ever have to watch their child starve,” Sunak told delegates in London.

He outlined Britain’s plans to host a “virtual hub” for innovation in food production, known as CGIAR (Consultative Group on International Agricultural Research), aimed at making global food systems more resilient to future shocks in a changing climate.

“We’ve already helped develop crops that are drought-resistant and even richer in vitamins, now feeding 100 million people across Africa. And we’re going further, launching a new U.K. CGIAR science center to drive cutting-edge research on flood-tolerant rice, disease-resistant wheat and much more. These innovations will reach millions across the poorest countries, as well as improving U.K. crop yields and driving down food prices,” Sunak said.

Somalia emergency

Somali President Hassan Sheikh Mohamud also addressed the summit, telling delegates that the country’s stabilization program, developed in partnership with Britain, was working on tackling his country’s humanitarian crisis.

Somalia is among the countries worst-hit by climate change and food insecurity. The government recently declared a state of emergency after 113,000 people were forced to flee their homes following extreme rainfall and extensive flooding, which also caused widespread damage to crops and farmland. The floods come a year after Somalia suffered its worst drought in 40 years.

Technological solutions

Can new technology end global food insecurity, like that endured by Somalia and many other poorer nations? It’s one tool in the box, said analyst Steve Wiggins, a food security specialist at the ODI development think tank.

“The fundamentals of global hunger are the fundamentals of poverty, marginalization, and people being in situations of extraordinary vulnerability. Those are the fundamentals of hunger and that’s what we have to drive towards,” he told VOA.

“Of course, there are technical advances that we get that we’re very happy for, which make things a little bit easier,” Wiggins added, highlighting innovations like solar-powered irrigation in Mali. “So, if you want to pump water onto your fields, it’s becoming increasingly easy without having to spend money on diesel to do so.”

Inequalities

Critics say the focus on technology ignores the main driver of food insecurity.

“This summit is welcome. I think some of the solutions are welcome. But I think it’s not going to be enough to tackle that huge problem of hunger, which has been with us for decades and which we seem to be going backwards in many steps,” said Nick Nisbett of the Institute of Development Studies.

“Technological solutions tend to focus on the supply side, so new tech for agriculture and supply chains and so on. But what we actually need to do is to tackle the inequalities that lie behind that hunger.”

“Possibly the simplest thing to do is actually to give people food or to give people the money to [go] out and buy and purchase food in [the] markets themselves,” Nisbett told VOA.
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