Day: September 24, 2023

NASA’s first asteroid samples fetched from deep space parachuted into the Utah desert Sunday to cap a seven-year journey.

In a flyby of Earth, the Osiris-Rex spacecraft released the sample capsule from 63,000 miles (100,000 kilometers) out. The small capsule landed four hours later on a remote expanse of military land, as the mothership set off after another asteroid.

Scientists estimate the capsule holds at least a cup of rubble from the carbon-rich asteroid known as Bennu but won’t know for sure until the container is opened. Some spilled and floated away when the spacecraft scooped up too much and rocks jammed the container’s lid during collection three years ago.

Japan, the only other country to bring back asteroid samples, gathered about a teaspoon in a pair of asteroid missions.

The pebbles and dust delivered Sunday represent the biggest haul from beyond the moon. Preserved building blocks from the dawn of our solar system 4.5 billion years ago, the samples will help scientists better understand how Earth and life formed.

Osiris-Rex, the mothership, rocketed away on the $1 billion mission in 2016. It reached Bennu two years later and, using a long stick vacuum, grabbed rubble from the small roundish space rock in 2020. By the time it returned, the spacecraft had logged 4 billion miles (6.2 billion kilometers).

NASA’s recovery effort in Utah included helicopters as well as a temporary clean room set up at the Defense Department’s Utah Test and Training Range. The samples will be flown Monday morning to a new lab at NASA’s Johnson Space Center in Houston. The building already houses the hundreds of pounds (kilograms) of moon rocks gathered by the Apollo astronauts more than a half-century ago.

The mission’s lead scientist, Dante Lauretta of the University of Arizona, will accompany the samples to Texas. The opening of the container in Houston in the next day or two will be “the real moment of truth,” given the uncertainty over the amount inside, he said ahead of the landing.

Engineers estimate the canister holds 250 grams (8.82 ounces) of material from Bennu, plus or minus 100 grams (plus or minus 3.53 ounces). Even at the low end, it will easily surpass the minimum requirement of the mission, Lauretta said.

It will take a few weeks to get a precise measurement, said NASA’s lead curator Nicole Lunning.

NASA plans a public show-and-tell in October.

Currently orbiting the sun 50 million miles (81 million kilometers) from Earth, Bennu is about one-third of a mile (one-half of a kilometer) across, roughly the size of the Empire State Building but shaped like a spinning top. It’s believed to be the broken fragment of a much larger asteroid.

During a two-year survey, Osiris-Rex found Bennu to be a chunky rubble pile full of boulders and craters. The surface was so loose that the spacecraft’s vacuum arm sank a foot or two (0.5 meters) into the asteroid, sucking up more material than anticipated and jamming the lid.

These close-up observations may come in handy late in the next century. Bennu is expected to come dangerously close to Earth in 2182 — possibly close enough to hit. The data gleaned by Osiris-Rex will help with any asteroid-deflection effort, according to Lauretta.

Osiris-Rex is already chasing after the asteroid Apophis and will reach it in 2029.

This was NASA’s third sample return from a deep-space robotic mission. The Genesis spacecraft dropped off bits of solar wind in 2004, but the samples were compromised when the parachute failed, and the capsule slammed into the ground. The Stardust spacecraft successfully delivered comet dust in 2006.

NASA’s plans to return samples from Mars are on hold after an independent review board criticized the cost and complexity. The Martian rover Perseverance has spent the past two years collecting core samples for eventual transport to Earth.
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The World Health Organization says there is a global uptick in cholera cases.

The number of cases reported last year was more than double those reported in 2021, the United Nations agency said.

The number of countries reporting cholera statistics also grew in 2022 by 25%, from 35 countries in 2021 to 44 countries last year.

Cholera can be a life-threatening disease, according to the U.S. Centers for Disease Control and Prevention, that can spread through unsafe food or water.  Cholera bacteria can spread from a person to drinking water or water used to grow food or prepare food.  Cholera can also spread when human feces with cholera enter the water supply.

The standard treatment for cholera has been a two-dose vaccination, but beginning in October 2022, the International Coordinating Group that manages emergency vaccine supplies, switched to a single-dose vaccine.

Last year, there were large cholera outbreaks, the WHO said. Seven countries –Afghanistan, Cameroon, Democratic Republic of the Congo, Malawi, NIgeria, Somalia and Syria – reported more than 10,000 suspected and confirmed cholera cases.

The WHO said the world is on track this year to continue the cholera upsurge with outbreaks currently in 24 countries “with some countries in the midst of acute crises.”  
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As Republican-led states have rushed to ban gender-affirming for minors, some families with transgender children found a bit of solace: At least they lived in states that would allow those already receiving puberty blockers or hormone therapy to continue.

But in some places, including Missouri and North Dakota, the care has abruptly been halted because medical providers are wary of harsh liability provisions in those same laws — one of multiple reasons that advocates say care has become harder to access even where it remains legal.

“It was a completely crushing blow,” said Becky Hormuth, whose 16-year-old son was receiving treatment from the Washington University Gender Center at St. Louis Children’s Hospital until it stopped the care for minors this month. Hormuth cried. Her son cried, too.

“There was some anger there, not towards the doctors, not toward Wash U. Our anger is towards the politicians,” she said. “They don’t see our children. They say the health care is harmful. They don’t know how much it helps my child.”

Since last year, conservative lawmakers and governors have prioritized restricting access to transgender care under the name of protecting children. At least 22 states have now enacted laws restricting or banning gender-affirming medical care for transgender minors. Most of the bans face legal challenges and enforcement on some of them has been put on hold by courts.

All the laws ban gender-affirming surgery for minors, although it is rare, with fewer than 3,700 performed in the U.S. on patients ages 12 to 18 from 2016 through 2019, according to a study published last month. It’s not clear how many of those patients were 18 when they received the surgeries.

There’s more variation, though, in how states handle puberty-blockers and hormone treatments under the new bans. Georgia’s law does not ban those for minors. The others do. But some states, including North Carolina and Utah, allow young people taking them already to continue. Others require the treatments to be phased out over time.

These treatments are accepted by major medical groups as evidence-based care that transgender people should be able to access.

James Thurow said the treatment at the Washington University center changed everything for his stepson, a 17-year-old junior at a suburban St. Louis high school who is earning As and Bs instead of his past Cs, has a girlfriend and a close group of friends.

“His depression, his anxiety had pretty much dissipated because he was receiving the gender-affirming care,” Thurow said. “He’s doing the best he’s ever done at school. His teachers were blown away at how quickly his grades shot up.”

For its part, the center said in a statement that it was “disheartened” to have to stop the care. Its decision followed a similar one from University of Missouri Health Care, where the treatment for minors stopped Aug. 28, the same day the law took effect.

Both blamed a section of the law that increased the liability for providers. Under it, patients can sue for injury from the treatment until they turn 36, or even longer if the harm continues past then. The law gives the health care provider the burden of proving that the harm was not the result of hormones or puberty-blocking drugs. And the minimum damages awarded in such cases would be $500,000.

Neither state Sen. Mike Moon, the Republican who was the prime sponsor of the Missouri ban, state Sen. Justin Brown nor state Rep. Dale Wright, whose committees advanced the measure, responded immediately to questions left Thursday by voicemail, email or phone message about the law’s intent.

In North Dakota, the law allows treatment to continue for minors who were receiving care before the law took effect in April. But it does not allow a doctor to switch the patient to a different gender dysphoria-related medication. And it allows patients to sue over injuries from treatment until they turn 48.

Providers there have simply stopped gender-affirming care, said Brittany Stewart, a lawyer at Gender Justice, which is suing over the ban in the state. “To protect themselves from criminal liability, they’ve just decided to not even risk it because that vague law doesn’t give them enough detail to understand exactly what they can and cannot do,” Stewart said.

Jasmine Beach-Ferrara, the executive director of the Campaign for Southern Equality, said it’s not just liability clauses that have caused providers to stop treatment.

Across the South, where most states have adopted bans on gender-affirming care for minors, she said she’s heard of psychologists who wrongly believe the ban applies to them and pharmacists who stop filling orders for hormones for minors, even in places where the laws are on hold because of court orders.

“It’s hard to overstate the level of kind of chaos and stress and confusion it’s causing on the ground,” she said, “particularly … for people who live in more rural communities or places where even before a law went into effect, it still took quite a bit of effort to get this care.”

Her organization is providing grants and navigation services to help children get treatment in states where it’s legal and available. That system is similar to networks that are helping women in states where abortion is not banned get care.

But there’s one key difference: gender-affirming care is ongoing. 

For 12-year-old Tate Dolney in Fargo, North Dakota, continuing care means traveling to neighboring Minnesota for medical appointments. “It’s not right and it’s not fair,” his mother, Devon Dolney, said at a news conference this month, “that our own state government is making us feel like we have to choose between the health and well-being of our child and our home.”

Hormuth’s son is on the waiting list for a clinic in Chicago, at least a five-hour drive away, but is looking at other options, too. Hormuth, a teacher, has asked also her principal to write a recommendation in case the family decides to move to another state.

“Should we have to leave?” she asked. “No one should have to have a plan to move out of state just because their kid needs to get the health care they need.”

In the meantime, the family did what many have: saving leftover testosterone from vials. They have enough doses stockpiled to last a year.
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The climactic end of a seven-year voyage comes Sunday when a NASA capsule is to land in the Utah desert, carrying to Earth the largest asteroid samples ever collected.

Scientists have high hopes for the sample, saying it will provide a better understanding of the formation of our solar system and how Earth became habitable.

The Osiris-Rex probe’s final, fiery descent through Earth’s atmosphere will be perilous, but the U.S. space agency is hoping for a soft landing, around 9 a.m. local (15H00 GMT), in a military test range in northwestern Utah.

Four years after its 2016 launch, the probe landed on the asteroid Bennu and collected roughly nine ounces (250 grams) of dust from its rocky surface.

Even that small amount, NASA says, should “help us better understand the types of asteroids that could threaten Earth” and cast light “on the earliest history of our solar system,” NASA Administrator Bill Nelson said.

“This sample return is really historic,” NASA scientist Amy Simon told AFP. “This is going to be the biggest sample we’ve brought back since the Apollo moon rocks” were returned to Earth.

But the capsule’s return will require “a dangerous maneuver,” she acknowledged.

Osiris-Rex is set to release the capsule — from an altitude of more than 108,000 kilometers — about four hours before it lands.

The fiery passage through the atmosphere will come in the last 13 minutes, as the capsule hurtles downward at a speed of more than 43,453 kph, with temperatures of up to 2,760 Celsius.

Its rapid descent, monitored by army sensors, will be slowed by two successive parachutes. Should they fail to deploy correctly, a “hard landing” would follow.

If it appears that the target zone 60 by 15 kilometers might be missed, NASA controllers could decide at the last moment not to release the capsule.

The probe would then keep its cargo and make another orbit of the sun. Scientists would have to wait until 2025 before trying a new landing.

If it succeeds, however, Osiris-Rex would head toward a date with another asteroid.

Once the tire-sized capsule touches down in Utah, a team in protective masks and gloves will place it in a net to be airlifted by helicopter to a temporary “clean room” nearby.

NASA wants this done as quickly and carefully as possible to avoid any contamination of the sample with desert sands, skewing test results.

On Monday, assuming all goes well, the sample will be flown by plane to NASA’s Johnson Space Center in Houston, Texas. There, the box will be opened in another “clean room,” the beginning of a days-long process.

NASA plans to announce its first results at a news conference on Oct. 11.

Most of the sample will be conserved for study by future generations. Roughly one-fourth of it will be immediately used in experiments, and a small amount will be sent to Japan and Canada, partners in the mission.

Japan had earlier given NASA a few grains from the asteroid Ryugu, after bringing 5.6 grams of dust to Earth in 2020 during the Hayabusa-2 mission. Ten years before, it had brought back a microscopic quantity from another asteroid.

But the sample from Bennu is much larger, allowing for significantly more testing, Simon said.

Asteroids are composed of the original materials of the solar system, dating to some 4.5 billion years ago, and have remained relatively intact.

They “can give us clues about how the solar system formed and evolved,” said Osiris-Rex program executive Melissa Morris.

“It’s our own origin story,” she said.

By striking Earth’s surface, “we do believe asteroids and comets delivered organic material, potentially water, that helped life flourish here on Earth,” Simon said.

Scientists believe Bennu, which is 500 meters in diameter, is rich in carbon — a building block of life on Earth — and contains water molecules locked in minerals.

Bennu had surprised scientists in 2020 when the probe, during the few seconds of contact with the asteroid’s surface, had sunk into the soil, revealing an unexpectedly low density, sort of like a children’s pool filled with plastic balls.

Understanding its composition could come in handy in the distant future.

There is a slight, but non-zero, chance (one in 2,700) that Bennu could collide catastrophically with Earth, though not until 2182.

But NASA last year succeeded in deviating the course of an asteroid by crashing a probe into it in a test, and it might at some point need to repeat that exercise, but with much higher stakes. 
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A 58-year-old man this week became the world’s second patient to receive a transplant of a genetically modified pig heart, the latest milestone in a growing field of medical research. 

Transplanting animal organs into humans, called xenotransplantation, could offer a solution to the chronic shortage of human organ donations. More than 100,000 Americans are currently on waiting lists for organ transplants. 

Both heart procedures were carried out by experts from the University of Maryland School of Medicine, with the first patient dying two months after his transplant last year due to “a multitude of factors including his poor state of health” prior to the operation, the university said in a statement Friday. 

‘Now I have hope’

The latest operation took place Wednesday with patient Lawrence Faucette. He was ineligible for a donated human heart due to pre-existing vascular disease and internal bleeding complications. 

Without the experimental transplant, the father of two and Navy veteran was facing near-certain heart failure. 

“My only real hope left is to go with the pig heart, the xenotransplant,” Faucette was quoted as saying prior to the procedure. “At least now I have hope, and I have a chance.” 

Following the transplant, Faucette was breathing on his own and the new heart was functioning well “without any assistance from supportive devices,” the university said. 

He was taking conventional anti-rejection drugs as well as receiving a new antibody therapy to prevent his body from damaging or rejecting the new organ. 

Transplanted pig kidney lasted 61 days

Xenotransplants are challenging because the patient’s immune system will attack the foreign organ. Scientists are trying to circumvent the problem by using organs from genetically modified pigs. 

In the past few years, doctors have transplanted kidneys from genetically modified pigs into brain-dead patients. 

The NYU Langone Hospital Transplant Institute in New York announced this month that a pig kidney transplanted into a brain-dead patient had functioned for a record-breaking 61 days. 

Early xenotransplantation research focused on harvesting organs from primates — for example, a baboon heart was transplanted into a newborn known as “Baby Fae” in 1984, but she survived only 20 days. 

Current efforts focus on pigs, which are thought to be ideal donors for humans because of their organ size, their rapid growth and large litters — and the fact they are already raised as a food source. 
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