Day: February 25, 2023

A man in Spain who was suspected of having the deadly Marburg disease tested negative Saturday and does not have the virus, the health ministry said.

Health authorities in Valencia earlier said they had detected the country’s first suspected case of the infectious disease that has led to the quarantining of more than 200 people in Equatorial Guinea.

The 34-year-old man, who had recently been in Equatorial Guinea, had been given the all-clear but would be tested again in the coming weeks, officials said.

He had been transferred from a private hospital to an isolation unit at the Hospital La Fe in Valencia while tests were being conducted, the Valencian regional health authorities said.

Three health staff who are treating the man were also isolated as a precautionary measure, authorities said.

Marburg virus can have a fatality rate of up to 88%, according to the World Health Organization. There are no vaccines or antiviral treatments approved to treat it.

Equatorial Guinea quarantined more than 200 people and restricted movement February 13 in its Kie-Ntem province, where the hemorrhagic fever was first detected.

The small central African country has so far reported nine deaths as well as 16 suspected cases of the disease, with symptoms including fever, fatigue, blood-stained vomit and diarrhea, according to the WHO.

Cameroonian authorities detected two suspected cases of Marburg disease February 13 in Olamze, a commune on the border with Equatorial Guinea, the public health delegate for the region, Robert Mathurin Bidjang, said February 14.

Cameroon had restricted movement along the border to try to avoid contagion.
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Spain has identified its first suspected case of Marburg disease. 

The Spanish patient is a 34-year-old man who had recently traveled to the Central African nation of Equatorial Guinea.  He was in a private hospital but has been transferred to an isolation unit at Hospital La Fe in Valencia for further tests, regional medical officials said.

Marburg virus disease, or MVD, according to the Centers for Disease Control and Prevention, “is a rare but severe hemorrhagic fever which affects both people and non-human primates … Primates [including people] can become infected with Marburg virus, and may develop serious disease with high mortality.” 

Spanish health officials said Saturday that more than 200 people in Equatorial Guinea have recently been quarantined because of Marburg disease.  

Earlier this month, two suspected cases of Marburg were detected in Cameroon near its border with Equatorial Guinea.  

The World Health Organization says that the “highly virulent disease” can have “a fatality ratio of up to 88%” and “is in the same family as the virus that causes Ebola virus disease.” 

There are no vaccines or antiviral treatments for Marburg.
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Uber Technologies Inc. said on Friday plans by the local government in India’s Delhi city to only allow electric vehicles to function as bike taxis would risk “finishing off the sector” and impact the mobility needs of millions.

Delhi’s plans, part of a new policy to regulate vehicles used by ride-hailing companies like Uber and rival Ola, are being finalized and will be rolled out soon, the Economic Times reported earlier this week.

Reuters could not immediately confirm those plans.

If implemented, this would mark an aggressive step towards the country’s ambitions to ramp up the transition to vehicles that run on clean energy to reduce oil imports and curb pollution.

Uber, in a blogpost, said any such move would put at risk the livelihood of over 100,000 drivers in the city.

“Steep and infeasible EV mandates risk finishing off the sector as we know it. The impact of such a decision on the livelihoods and mobility needs of millions of Delhiites is clear,” San Francisco-headquartered Uber said, urging the government to initiate industry dialog.

Uber has set a 2040 target for 100% of its rides to be in zero-emission vehicles, public transport or with micro-mobility, including in India.

Earlier this month, Uber announced plans to introduce 25,000 EVs over three years in India. Electric cars will however still be a fraction of Uber’s current overall active fleet of 300,000 vehicles in India.

On Sunday, the Delhi government in newspaper ads said digital platforms offering two-wheeler bike taxi rides should not do so as it violates certain existing transport rules.

Uber, which offers bike rides in Delhi and many other states in India, did not respond to a Reuters request for a comment on the advertisement.
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The Biden administration is preparing for a worst-case scenario if a conservative federal judge rules in favor of a lawsuit seeking to restrict access to one of the two drugs typically used to induce a medicated abortion.

Two drugs, mifepristone and misoprostol, can be taken by women at home and are used for just over half of U.S. abortions. But that could be quickly changed by a lawsuit filed by an anti-abortion group in Texas that claims the Food and Drug Administration wrongly approved mifepristone for use more than 23 years ago.

The case is before a federal judge appointed by former President Donald Trump. A ruling in favor of the abortion opponents could immediately shut down the sale of the drug, but women would still have access to medicated abortions with a regimen of misoprostol.

Vice President Kamala Harris promised on Friday that the White House would push back on efforts to ban the drug, as she gathered a group of nearly a dozen doctors and abortion rights advocates to discuss a plan for responding to the looming threat to access to medical abortions.

“There are now partisan and political attacks attempting to question the legitimacy of a group of scientists and doctors who have studied the significance of this drug,” Harris said. “There is now an attempt by politicians to remove it from the ability of doctors to prescribe and the ability of people to receive.”

The lawsuit against mifepristone was filed by the Alliance for Defending Freedom, which was also involved in the Mississippi case that led to Roe v. Wade being overturned. It’s the latest fallout in the struggle over reproductive care that the Democratic administration must grapple with since the Supreme Court overturned the constitutional right to an abortion last year.

Harris did not publicly lay out how the administration plans to respond if a ruling that halts the sale of the drug nationwide comes down on Friday.

‘Medication abortion is not going away’

Health and Human Services Secretary Xavier Becerra, meanwhile, was in California on Friday to meet leaders from Planned Parenthood to talk about access to the abortion drugs.

Dr. Kristyn Brandi said she told the vice president on Friday that the ruling could trigger widespread confusion over the accessibility of medicated abortion in the U.S. Brandi, who is chair of the Physicians for Reproductive Health, said she already fields calls at her New Jersey clinic from women asking if medicated abortion is legal in the state.

“It’s a really important thing to communicate with people: medication abortion is not going away,” Brandi said.

She added that Harris expressed support for immediately challenging the ruling if it shuts down access to mifepristone.

Clinics and telehealth providers have been preparing for a ruling that shuts down access to mifepristone, ordering more doses of misoprostol so they can offer medication abortions with just that one drug. They will have to change the way they counsel patients, telling them that misoprostol-only abortions are slightly less effective and sometimes more painful than abortions done with both drugs.

Abortions using both drugs “can be as effective as 98% or more,” while misoprostol-only abortions are up to about 95% effective, Melissa Grant, chief operating officer of the Carafem abortion clinic, told The Associated Press.

Mifepristone dilates the cervix and blocks the action of the hormone progesterone, which enables a pregnancy to continue. Misoprostol causes contractions that empty the uterus. Typically, mifepristone is taken by mouth first, followed by misoprostol a day or two later.

Studies show medication abortions are safe and effective, though with a slightly lower success rate than ones done by procedure in a clinic.

Another lawsuit filed

With the Texas decision pending, a dozen Democratic-controlled states filed their own lawsuit in federal court against the FDA on Thursday in Washington. The lawsuit seeks to make it easier for woman to access the drug and alleges that several FDA requirements for prescribing and dispensing it are “burdensome, harmful and unnecessary.”

When the FDA approved mifepristone in 2000 it placed several safety restrictions on its use, including limiting dispensing to specialty clinics and requiring women to pick up the drug in person. The Biden administration had sought to expand access to medicated abortions in light of the Supreme Court’s ruling, with an FDA announcement this year that broadened the pill’s access through retail and mail-order pharmacies.

But several limitations remain, such as one that doctors must be specially certified to prescribe the drug.

Several medical groups have long opposed those requirements, pointing to the low rate of side effects seen with mifepristone compared with other medications that don’t carry any certification requirements.
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