Day: February 20, 2023

The U.N. in Malawi has launched an urgent appeal for aid to deal with the impact of a record cholera outbreak that has so far killed nearly 1,450 people and infected 45,000.  

Local health experts say if urgent action isn’t taken to scale up the response, the number of cases could double in the next few months.

The U.N. says the flash appeal seeks to raise $45.3 million to provide life-saving aid to thousands of people in Malawi devastated by the outbreak.

In a statement released Monday, the U.N. said the appeal aims to assist four million people in Malawi, including 56,000 refugees and asylum seekers who are at the highest risk in the outbreak.

The current outbreak started in March last year and has spread to all 29 districts of Malawi.

Rebecca Adda-Dontoh, the U.N. resident coordinator in Malawi, told reporters Monday that more assistance is needed to stop the outbreak.

“So much work has been done but a lot more needs to be done,” she said. “We have focused on health, we have focused on WASH (water, sanitation and hygiene). The two are very important but there are also other sectors like nutrition, protection and even logistics because we need to be able to move supplies from one point to the other.”

Adda-Dontoh said the needed assistance would complement what various donor partners have already contributed.

“The U.N. itself has mobilized already close to $10 million,” she said. “You heard the EU; you heard the U.K. here saying they had already contributed over 500,000 euros for the EU and also over 500,000 pounds for the U.K. Even the government of Malawi is on the ground and already contributed.”   

Local media have reported that Malawi needs an additional $40 million for its national plan on cholera response.

Cases of cholera in Malawi have increased since the beginning of January, worsening the country’s largest outbreak in the past two decades.

Malawian President Lazarus Chakwera said last week, when he launched a national anti-cholera campaign, that the country’s health facilities were recording between 500 to 600 cholera cases every day.

The U.N. said that health experts have warned that Malawi could record between 64,000 and 100,000 more cases of cholera within the next three months unless urgent action is taken to scale up the response.
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A growing number of startups are using artificial intelligence to replicate human voices. A company is creating synthetic voices for organizations to use for advertising, marketing and training. Phil Dierking reports. Videographer and video editor: Philip Dierking
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When COVID-19 hit in 2020, Ghenya Grondin of Waltham, Massachusetts, was a postpartum doula – a person charged with helping young couples navigate the first weeks of their newborn child’s life at home.

Grondin, now aged 44, was infected with SARS-CoV-2 in mid-March of that year – before there were tests, before social distancing or masks, and many months before the medical community recognized long COVID as a complication of COVID-19.

She is part of a community of first-wave long-haulers who faced a new disease without a roadmap or support from the medical establishment.

Three years later, at least 65 million people worldwide are estimated to have long COVID, according to an evidence review published last month in Nature Reviews Microbiology. More than 200 symptoms have been linked to the syndrome – including extreme fatigue, difficulty thinking, headaches, dizziness when standing, sleep problems, chest pain, blood clots, immune dysregulation, and even diabetes.

There are no proven treatments but research is underway.

People infected later in the pandemic had the benefit of vaccination, which “protects at least to some degree” from long COVID, said Dr. Bruce Levy, a Harvard pulmonologist and a co-principal investigator of the National Institute of Health’s $1.15 billion U.S. RECOVER trial, which aims to characterize and find cures for the disease.

“The initial variant of the virus caused a more severe illness than we’re seeing currently in most patients,” he said.

According to the University of Washington’s Institute of Health Metrics and Evaluation, in the first two years of the pandemic women were twice as likely as men to develop long COVID, and 15% of all of those affected at three months continued to experience symptoms beyond 12 months.

An analysis of thousands of health records by the RECOVER trial found that non-Hispanic white women in wealthier areas were more likely than others to have a long COVID diagnosis. Researchers said that likely reflected disparities in access to health care, and suggests that many cases of long COVID among people of color are not being diagnosed.

Grondin grew concerned when she continued to have symptoms three months after her initial infection – but there was no name for it then.

“I just kept saying to my husband, something isn’t right,” she said.

Like her fellow long-haulers, she has experienced a host of symptoms, including fatigue, sleep apnea, pain, cognitive dysfunction, and in her case, a brain aneurysm. She described a frightening moment when she was driving a car with her toddler in the back and had a seizure that left her in the path of oncoming traffic.

She has since been diagnosed with long COVID and can no longer work.

“It just feels like a constant punch in the face,” said Grondin.

Scientists are still working out why some people infected with COVID develop long-term symptoms, but syndromes like this are not new. Other infections such as Lyme disease can result in long-term symptoms, many of which overlap with long COVID.

Leading theories of the root causes of long COVID include the virus or viral proteins remaining in the tissues of some individuals; the infection causing an autoimmune response; or the virus reactivating latent viruses, leading to inflammation that damages tissue.

Kate Porter, 38, of Beverly, Massachusetts, a project manager for a financial services company, believes she was infected on a flight back from Florida in late March of 2020.

She had daily fevers for seven months, muscle weakness, shortness of breath, and excruciating nerve pain.

“I don’t think people realize how brutal physically everything was,” she said. In one of her darker moments, Porter recalled, “I cried on the floor begging for something to take me peacefully. I’ve never been like that.”

Frustrated by the lack of answers from a list of 10 specialists she has seen, Porter has explored alternative medicine. “It has opened me up to other remedies,” she said.

Although her health is much improved now, she still suffers from near daily migraines and neck pain she fears may never go away.

Genie Stevens, 65, a director of climate education, got infected while traveling from her home in Santa Fe to Cape Cod in late March 2020 to visit her mother, and never left. “It completely upended my life,” she said.

She went to an emergency department seeking tests and was told there were none – the typical answer in the spring of 2020, when scientists were scrambling to understand the nature of the virus and tests were being rationed. She was sent home to manage on her own.

A lifelong practitioner of meditation, Stevens took solace there, finding it eased her symptoms.

Confined to her bed that spring, she focused on an ancient crabapple tree outside her room. “I watched every bud unfurl.”

Although largely recovered, Stevens still has flare-ups of brain fog, exhaustion and high-pitched ringing in her ears when she pushes too hard. “This is the astoundingly maddening part of the illness. I feel totally fine, and then bam.”
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United Nations members gather Monday in New York to resume efforts to forge a long-awaited and elusive treaty to safeguard the world’s marine biodiversity. 

Nearly two-thirds of the ocean lies outside national boundaries on the high seas where fragmented and unevenly enforced rules seek to minimize human impact. 

The goal of the U.N. meetings, running through March 3, is to produce a unified agreement for the conservation and sustainable use of those vast marine ecosystems. The talks, formally called the Intergovernmental Conference on Marine Biodiversity of Areas Beyond National Jurisdiction, resume negotiations suspended last fall without agreement on a final treaty. 

“The ocean is the life support system of our planet,” said Boris Worm, a marine biologist at Canada’s Dalhousie University. “For the longest time, we did not feel we had a large impact on the high seas. But that notion has changed with expansion of deep-sea fishing, mining, plastic pollution, climate change,” and other human disturbances, he said. 

The U.N. talks will focus on key questions, including: How should the boundaries of marine protected areas be drawn, and by whom? How should institutions assess the environmental impacts of commercial activities, such as shipping and mining? And who has the power to enforce rules? 

“This is our largest global commons,” said Nichola Clark, an oceans expert who follows the negotiations for the nonpartisan Pew Research Center in Washington. “We are optimistic that this upcoming round of negotiations will be the one to get a treaty over the finish line.” 

The aim of the talks is not to designate marine protected areas, but to establish a mechanism for doing so. 

“The goal is to set up a new body that would accept submissions for specific marine protected areas,” Clark said. 

Marine biologist Simon Ingram at the University of Plymouth in England says there’s an urgent need for an accord. 

“It’s a really pressing time for this — especially when you have things like deep-sea mining that could be a real threat to biodiversity before we’ve even been able to survey and understand what lives on the ocean floor,” Ingram said. 

Experts say that a global oceans treaty is needed to enforce the U.N. Biodiversity Conference’s recent pledge to protect 30% of the planet’s oceans, as well as its land, for conservation. 

“We need a legally binding framework that can enable countries to work together to actually achieve these goals they’ve agreed to,” said Jessica Battle, an expert on oceans governance at World Wide Fund for Nature 

U.S. Assistant Secretary of State for Oceans and International Environmental and Scientific Affairs Monica Medina said the treaty is a priority. 

“This agreement seeks to create, for the first time, a coordinated approach to establishing marine protected areas on the high seas,” she said. “It’s time to finish the job.” 

Officials, environmentalists and representatives of global industries that depend on the sea are also watching negotiations closely. 

Gemma Nelson, a lawyer from Samoa and an Ocean Voices fellow at the University of Edinburgh, said that small Pacific and Caribbean island countries were “especially vulnerable to global ocean issues,” such as pollution and climate change, which generally they did not cause nor have the resources to easily address. 

“Getting the traditional knowledge of local people and communities recognized as valid” is also essential to protect both ecosystems and the ways of life of Indigenous groups, she said. 

With nearly half the planet’s surface covered by high seas, the talks are of great importance, said Gladys Martínez de Lemos, executive director of the nonprofit Interamerican Association for Environmental Defense focusing on environmental issues across Latin America. 

“The treaty should be strong and ambitious, having the authority to establish high and fully protected areas in the high seas,” she said. “Half of the world is at stake these weeks at the United Nations.” 
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