Day: December 18, 2021

Egyptian health authorities said they have identified the country’s first cases of the highly transmissible omicron variant of the coronavirus.

Three people were found to have the variant among 26 travelers who tested positive for coronavirus at Cairo International Airport, the Health Ministry said in a statement late Friday. It didn’t say where the three came from.

The local Masrawy news outlet reported the three were among travelers from South Africa.

The ministry said two of the people infected showed no symptoms, while the third suffered from mild symptoms. The three have been isolated in a Cairo hospital, it said.

Authorities on Friday reported more than 900 confirmed new cases of coronavirus and 43 deaths over the previous 24 hours.

Egypt has reported a total 373,500 cases, including 21,277 fatalities, since the pandemic began. 

 
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The head of the World Health Organization says the continuing surge of COVID-19 cases is a result of the unequal distribution of vaccines.

Speaking at the First International Conference on Public Health in Africa, WHO Director-General Tedros Adhanom Ghebreyesus noted that it has been just over a year since the first COVID-19 vaccines began to be administered.

He said, “A year ago, we all hoped that by now vaccines would be helping us all emerge from the long, dark tunnel of the pandemic. Instead, as we enter the third year of the pandemic, the death toll has more than tripled, and the world remains in its grip. COVID-19 has now killed more than 5 million people. And they’re just the reported deaths.”

Tedros told the virtual conference that the rapid development of not one, but several safe and effective vaccines, is a triumph of science. But he said, “the inequitable distribution of vaccines has been a failure for humanity.”

The WHO chief said that while more than 8.5 billion doses have been administered globally – the largest vaccination campaign in history, only 8% of Africa’s eligible population is fully vaccinated.

“We have often said that as long as vaccine inequity persists, the more opportunity the virus has to spread and mutate in ways no one can prevent or predict. And so, we have omicron,” the director-general said.

Tedros noted, however, that vaccine-sharing programs are “picking up speed.” He said, “In the past 10 weeks, COVAX has shipped more vaccines than in the first nine months of the year combined.”

 
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Pfizer Inc on Friday forecast that the COVID-19 pandemic would not be behind us until 2024 and said a lower-dose version of its vaccine for 2- to 4-year-olds generated a weaker immune response than expected, potentially delaying authorization.

Pfizer Chief Scientific Officer Mikael Dolsten said in a presentation to investors that the company expects some regions to continue to see pandemic levels of COVID-19 cases over the next year or two. Other countries will transition to “endemic” with low, manageable caseloads during that same time period.

By 2024, the disease should be endemic around the globe, the company projected.

“When and how exactly this happens will depend on evolution of the disease, how effectively society deploys vaccines and treatments, and equitable distribution to places where vaccination rates are low,” Dolsten said. “The emergence of new variants could also impact how the pandemic continues to play out.”

Pfizer developed its COVID-19 vaccine with Germany’s BioNTech SE, and currently expects it to generate revenue of $31 billion next year. It plans to make 4 billion shots next year.

The drugmaker also has an experimental antiviral pill called Paxlovid which reduced hospitalizations and deaths in high-risk individuals by nearly 90% in a clinical trial.

Three analysts estimate sales of $15 billion to $25 billion for it next year, according to IBES data from Refinitiv.

Pfizer’s forecast came after the emergence of the omicron variant last month, which has more than 50 mutations compared with the original version of the virus. That has reduced the effectiveness of two doses of the vaccine against infection, and spurred fear of rapid spread around the globe.

Prior to the omicron variant, top U.S. disease doctor Anthony Fauci forecast the pandemic would end in 2022 in the United States.

Pediatric vaccine

The Pfizer vaccine is authorized in the United States for people aged 5 and older. But it said on Friday that its study in children between the ages of 2 and 4 who were given two 3-microgram doses of the vaccine found it did not create the same immune response that a larger dose of the vaccine had in older children.

The 3-microgram dose did generate a similar immune response in children aged 6 to 24 months, the company said. The company said it will now test a three-dose course in both age groups, as well as in older children. It had previously expected data from 2- to 4-year-olds this year but said it did not expect the delay would meaningfully change plans to file for emergency use authorization in the second quarter of 2022.

Pfizer and BioNTech have also been developing a version of their vaccine tailored to combat the quick-spreading omicron variant, although they have not decided whether it will be needed. They expect to start a clinical trial for the updated vaccine in January, Pfizer executives said.

Variant-specific shots, if needed, could boost sales in 2022. The highly transmissible omicron variant of the coronavirus has been det

ected in over 77 countries and has spread to about one-third of U.S. states.The vaccine was around 95% effective in the adult clinical trial, but Pfizer has said that immunity wanes some months after the second dose. Early data suggests that three doses of the shot may be necessary to protect against the omicron variant. 

 
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New York state reported Friday that just over 21,000 people had tested positive for COVID-19 the previous day, the highest single-day total for new cases since testing became widely available.

Just under half of the positive results were in the city, where lines were growing at testing stations, the Rockettes Christmas show was canceled for the season and some Broadway shows nixed performances because of outbreaks among cast members.

One-day snapshots of virus statistics can be an unreliable way to measure trends, but the new record punctuated a steady increase that started in the western part of the state in late October and has taken off in New York City in the past week as the omicron variant spreads.

“This is changing so quickly. The numbers are going up exponentially by day,” Gov. Kathy Hochul said during a Friday appearance on CNN.

The steep rise in infections should be of great concern, but it was inevitable, given the quick spread of the newest variant, said Dr. Denis Nash, the executive director of the Institute for Implementation Science in Population Health at the City University of New York.

“We were already headed for a winter surge with delta, which is a very concerning thing in its own right,” Nash said.

“But then you layer on top of that the new omicron variant, which is more transmissible from an infection standpoint,” he said, noting that current vaccines may be unable to contain the “more invasive” new variant.

Statewide, New York averaged 13,257 positive tests per day over the seven-day period that ended Thursday. That is up 71% from two weeks ago.

The state’s previous one-day high for positive tests came on Jan. 14, 2021, when just under 20,000 people tested positive.

New York City Mayor Bill de Blasio has warned that omicron is in “full force,” but said the city’s hospitals are “very strong and stable right now” and far better able to handle COVID-19 than when the pandemic began. Treatments have improved, and more than 70% of eligible city residents are fully vaccinated, he noted. 
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