Day: September 22, 2021

Scientists have found evidence of a resistant form of malaria in Uganda, a worrying sign that the top drug used against the parasitic disease could ultimately be rendered useless without more action to stop its spread.

Researchers in Uganda analyzed blood samples from patients treated with artemisinin, the primary medicine used for malaria in Africa in combination with other drugs. They found that by 2019, nearly 20% of the samples had genetic mutations, suggesting the treatment was ineffective. Lab tests showed it took much longer for those patients to get rid of the parasites that cause malaria.

Drug-resistant forms of malaria were previously detected in Asia, and health officials have been nervously watching for any signs in Africa, which accounts for more than 90% of the world’s malaria cases. Some isolated drug-resistant strains of malaria have previously been seen in Rwanda.

“Our findings suggest a potential risk of cross-border spread across Africa,” the researchers wrote in The New England Journal of Medicine, which published the study Wednesday.

The drug-resistant strains emerged in Uganda rather than being imported from elsewhere, they reported. They examined 240 blood samples over three years.

Malaria is spread by mosquito bites and kills more than 400,000 people every year, mostly children under 5 and pregnant women.

Resistance has ‘a foothold’

Dr. Philip Rosenthal, a professor of medicine at the University of California- San Francisco, said that the new findings in Uganda, after past results in Rwanda, “prove that resistance really now has a foothold in Africa.”

Rosenthal, who was not involved in the new study, said it was likely there was undetected drug resistance elsewhere on the continent. He said drug-resistant versions of malaria emerged in Cambodia years ago and have now spread across Asia. He predicted a similar path for the disease in Africa, with deadlier consequences given the burden of malaria on the continent.

Dr. Nicholas White, a professor of tropical medicine at Mahidol University in Bangkok, described the new paper’s conclusions about emerging malaria resistance as “unequivocal.”

“We basically rely on one drug for malaria, and now it’s been hobbled,” said White, who also wrote an accompanying editorial in the Journal.

He suggested that instead of the standard approach, where one or two other drugs are used in combination with artemisinin, doctors should now use three, as is often done in treating tuberculosis and HIV.

White said public health officials need to act to stem drug-resistant malaria, by beefing up surveillance and supporting research into new drugs, among other measures.

“We shouldn’t wait until the fire is burning to do something, but that is not what generally happens in global health,” he said, citing the failures to stop the coronavirus pandemic as an example.
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Scientists with the National Snow and Ice Data Center (NSIDC) in the U.S. state of Colorado said Wednesday that, as summer was ending in the Northern Hemisphere, Arctic sea ice had shrunk less in 2021 than in other recent years. 

Supported by NASA and other federal agencies, the NSIDC is part of the Cooperative Institute for Research in Environmental Sciences at the University of Colorado in Boulder. It is among the research organizations that monitor the ebb and flow of the Arctic ice pack. Scientists with the center determined the ice pack reached its minimum extent for the year on September 16.

Sea ice extent is defined as the total area in which ice concentration is at least 15% 

This year, satellite observations determined Arctic ice covered a minimum of 1.82 million square kilometers, which NSIDC scientists said was the highest minimum coverage since 2014, and the 12th lowest in 43 years of satellite records. 

In a statement, NSIDC Director Mark Serreze said, “We had a reprieve this year — a cool and stormy summer with less ice melt. But the amount of old, thick sea ice is as low as it has ever been in our satellite record.” 

The NSIDC said the last 15 years have produced the lowest 15 sea ice extents in the satellite record. The amount of old, multiyear ice — that is, ice that has remained frozen through at least one summer melt season — is at one of the lowest levels in the ice age record, which began in 1984. 

The center cautioned the Arctic Sea ice extent figures were preliminary, as continued melting could still push the ice minimum extent lower before the early winter freeze begins. NSIDC will issue a formal announcement at the beginning of October with full analysis of the possible causes behind this year’s ice conditions.

 
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The World Health Organization is issuing new guidelines on improving global air quality, which it says could save many of the seven million lives that are lost each year to pollution.

WHO Director-General Tedros Adhanom Ghebreyesus says inhaling dirty air increases the risk of pneumonia, asthma, and chronic obstructive pulmonary diseases, as well as noncommunicable ailments including heart disease, stroke and cancers. 

“Air pollution is a health threat in all countries but especially for vulnerable groups in low- and middle-income countries with poor air quality due to urbanization and rapid economic development and air pollution in the home caused by cooking, heating and lighting,” he said. 

Since the WHO’s last global update in 2005, a new body of evidence has emerged showing that humans suffer damage to their health at lower concentrations of air pollution than previously believed. 

Consequently, the WHO recommends lower air quality levels for five key pollutants, including nitrogen dioxide, sulfur dioxide, and carbon monoxide. 

Maria Neira, director of the WHO’s department of environment, climate change and health, says a changeover to cleaner energy will improve people’s health and mitigate global warming.

“Moving to renewable and clean sources of energy because [of] this will have a very positive impact on reducing the greenhouse gases emission and tackling the causes of climate change and reducing air pollution,” she said. “Both are critical pillars of our health.” 

Besides improving health and saving lives, reducing air pollution could also have enormous economic benefits.

The World Bank estimates the global cost associated with health damage from ambient air pollution stands at $5.7 trillion a year. 

 
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Amnesty International is accusing the world’s leading pharmaceutical companies of creating an “unprecedented human rights crisis” by failing to provide enough COVID-19 vaccines for the world’s poorest nations. 

In a report issued Wednesday, the human rights advocacy group says AstraZeneca, Johnson & Johnson, Moderna, Novavax and the partnership of Pfizer and BioNTech have “failed to meet their human rights responsibilities” by refusing to participate in global vaccine sharing initiatives and share vaccine technology by waiving their intellectual property rights.

Amnesty says only a “paltry” 0.3% of the 5.76 billion doses of COVID-19 vaccines distributed around the world have gone to low-income countries, while 79% have gone to upper-middle and high-income countries. It says the disparity is “pushing weakened health systems to the very brink and causing tens of thousands of preventable deaths every week,” especially in parts of Latin America, Africa and Asia. 

The organization says Pfizer, BioNTech and Moderna alone are set to make $130 billion combined by the end of 2022.

“Profits should never come before lives,” said Agnès Callamard, Amnesty International’s secretary general. 

Amnesty is calling on governments and pharmaceutical companies to immediately deliver 2 billion doses of COVID-19 vaccines to low and lower-middle income countries to meet the World Health Organization’s goal of vaccinating 40% of the population of such countries by the end of the year. 

COVID Summit

The report was issued ahead of U.S. President Joe Biden’s virtual COVID Summit, held in conjunction with this week’s United Nations General Assembly. Biden is expected to announce a global vaccination target of 70% along with an additional purchase of 500 million doses of the two-shot Pfizer vaccine, bringing the United States’ overall donations to more than 1.1 billion doses.

“America is committed to beating COVID-19. Today, the United States is doubling our total number of global donated vaccines to more than 1.1 billion. For every shot we’ve put in an American arm to date, we are donating three shots globally,” U.S. Secretary of State Antony Blinken said Wednesday on Twitter. 

Extreme poverty

The Asian Development Bank says the pandemic likely pushed as many as 80 million people in Asia’s developing nations into extreme poverty last year. A report issued Tuesday by the Manila-based institution said the region’s developing economies will likely grow at a slower-than-expected pace in 2021 due to lingering COVID-19 outbreaks and the slow pace of vaccination efforts

The ADB is predicting Southeast Asian economies to grow by just 3.1 percent this year, a drop from the 4.4 percent rate forecast in its economic outlook back in April.

Some information for this report came from the Associated Press, Reuters and Agence France Presse (AFP).

 
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The two biggest economies and largest carbon polluters in the world announced separate financial attacks on climate change Tuesday. 

Chinese President Xi Jinping said his country will no longer fund coal-fired power plants abroad, surprising the world on climate for the second straight year at the U.N. General Assembly. That came hours after U.S. President Joe Biden announced a plan to double financial aid to poorer nations to $11.4 billion by 2024 so those countries could switch to cleaner energy and cope with global warming’s worsening impacts. That puts rich nations close to within reach of its long-promised but not realized goal of $100 billion a year in climate help for developing nations. 

“This is an absolutely seminal moment,” said Xinyue Ma, an expert on energy development finance at Boston University’s Global Development Policy Center. 

This could provide some momentum going into major climate talks in Glasgow, Scotland, in less than six weeks, experts said. Running up to the historic 2015 Paris climate deal, a joint U.S.-China agreement kickstarted successful negotiations. This time, with China-U.S. relations dicey, the two nations made their announcements separately, hours and thousands of miles apart. 

“Today was a really good day for the world,” United Kingdom Prime Minister Boris Johnson, who is hosting the upcoming climate negotiations, told Vice President Kamala Harris. 

United Nations Secretary-General Antonio Guterres, who has made a frenetic push this week for bigger efforts to curb climate change called the two announcements welcome news, but said “we still have a long way to go” to make the Glasgow meeting successful. 

Depending on when China’s new coal policy goes into effect, it could shutter 47 planned power plants in 20 developing countries that use the fuel that emits the most heat-trapping gases, about the same amount of coal power as from Germany, according to the European climate think-tank E3G. 

“It’s a big deal. China was the only significant funder of overseas coal left. This announcement essentially ends all public support for coal globally,” said Joanna Lewis, an expert on China, energy and climate at Georgetown University. “This is the announcement many have been waiting for.”

From 2013 to 2019, data showed that China was financing 13% of coal-fired power capacity built outside China – “far and away the largest public financier,” said Kevin Gallagher, who directs the Boston University center. Japan and South Korea announced earlier this year that they were getting out of the coal-financing business. 

With all three countries pulling out of financing coal abroad “that sends a signal to the global economy. This is a sector that’s fast becoming a stranded asset,” Gallagher said. 

While this is a big step it is not quite a death knell for coal, said Byford Tsang, a policy analyst for E3G. That’s because China last year added as much new coal power domestically as was just potentially cancelled abroad, he said. 

Tsang cautioned that the one-sentence line in Xi’s speech that mentioned this new policy lacked details like effective dates and whether it applied to private funding as well as public funding. 

What also matters is when China stops building new coal plants at home and shutters old ones, Tsang said. That will be part of a push in the G-20 meetings in Italy next month, he said. “The Chinese are going to respond to international pressure, rather than just American bilateral pressure right now,” said Deborah Seligsohn, an expert on China’s politics and energy at Villanova University. 

“A coal-free energy mix is still decades in the future” because coal power plants typically operate for 50 years or more, said Stanford University environment director Chris Field. 

Many nations that are trying to build their economies — including top polluters China and India — have long argued they needed to industrialize with fossil fuels, like developed nations had already done. Starting in 2009 and then with “a grand bargain” in 2015 in Paris, richer nations promised $100 billion a year in financial help to poorer nations to make the switch from dirty to clean fuel, World Resources Institute climate finance expert Joe Thwaites said. 

But as of 2019, the richer nations were only providing $80 billion a year, according to the Organization for Economic Co-operation and Development. So, when rich nations like the United States asked poorer ones to do more “it gives any other country a very easy retort,” Thwaites said: “‘You took out commitments and you haven’t delivered on those either.” 

In April, Biden announced he would double the Obama era financial aid pledge of $2.85 billion a year to $5.7 billion. On Tuesday he announced that he hopes to double that to $11.4 billion a year starting in 2024, but he does need passage from Congress. 

The European Union has been doling out $24.5 billion a year with the European Commission recently upping that to more than $4.7 billion over seven years. “The Europeans are doing a lot more and the Americans are lagging behind,” Thwaites said. 

He said several studies calculate that based on the U.S. economy, population and carbon pollution, it should be contributing 40% to 47% of the $100 billion fund to be doing its fair share. 

But Congressional Republicans aren’t convinced. “We shouldn’t be contributing to a fund that picks winners and losers and further subsidizes China in the process,” said Rep. Garret Graves, R-Louisiana, the ranking Republican on the House Climate Committee. 

The time for global grandstanding is over, said Princeton University climate science and international affairs professor Michael Oppenheimer said. “It’s what’s happening on the ground that matters.” 

“Accelerating the global phase out of coal is the single most important step” to keeping the Paris agreement’s key warming limit within reach, said U.N. chief Guterres. 
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The delta variant of the coronavirus has overtaken all other variants of concern, the World Health Organization said Tuesday. 

“Less than 1% each of alpha, beta and gamma are currently circulating. It’s really predominantly delta around the world,” said Maria Van Kerkhove, the World Health Organization’s technical lead on COVID-19. 

According to Van Kerkhove, the delta variant is so highly transmissible it has replaced other variants circulating around the world. 

Hundreds of people demonstrated Tuesday in Australia’s second-largest city against coronavirus restrictions the government imposed on the construction industry. 

Officials announced that construction sites in Melbourne would be closed for two weeks amid concerns that the movement of workers was contributing to the spread of COVID-19. 

Construction workers are also now required to have received at least one dose of a coronavirus vaccine before being allowed to return to work. 

Victoria state, where Melbourne is located, reported 603 new cases on Tuesday, the most infections there in a single day this year. 

In New Zealand, Prime Minister Jacinda Ardern announced Tuesday that fines for breaking coronavirus protocols would increase starting in November. 

The changes would increase the fine for someone intentionally failing to comply with a COVID-19 order from about $2,800 to $8,400. Those breaking the restrictions could also face up to six months in prison. 

Businesses that violate coronavirus restrictions could face fines of up to $10,500. 

“Our success has been really based on the fact that people by and large have been compliant,” Ardern said at a news conference. “However, there has been the odd person that has broken the rules and put others at risk.” 

Meanwhile, Governor Jay Inslee, of the western U.S. state of Washington, is asking the federal government for help dealing with the strain on hospitals as the delta variant drives large numbers of infections. 

Inslee sent a letter Monday to White House pandemic coordinator Jeffrey Zients saying hospitals in his state are at or beyond capacity and that he is requesting military personnel to help staff hospitals. 

“Once the delta variant hit Washington state, COVID-19 hospitalizations skyrocketed,” Inslee said. “From mid-July to late August, we saw hospitalizations double about every two weeks. The hospitals have surged to increase staffed beds and stretch staff and have canceled most non-urgent procedures but are still over capacity across the state.” 

New daily infections and the number of people hospitalized in Washington are at or near their highest levels during the pandemic. 

Washington health officials report 69% of people ages 12 years and older in the state are fully vaccinated. 

That is higher than the national figure, with the Centers for Disease Control and Prevention reporting 64% of the population ages 12 and older being fully vaccinated. 

The new death toll from the virus in the United States was 2,302 on Monday — the highest recorded since March, according to data from the Johns Hopkins University Coronavirus Resource Center.

Some information for this report came from The Associated Press and Reuters. 

 
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