Category: Silicon Valley

ALBUQUERQUE, NEW MEXICO — A team of Italian researchers reached the edge of space Thursday morning, flying aboard Virgin Galactic’s rocket-powered plane as the company prepares for monthly commercial flights.

The flight launched from Spaceport America in the New Mexico desert, with two Italian Air Force officers and an engineer with the National Research Council of Italy focusing on a series of microgravity experiments during their few minutes of weightless.

One wore a special suit that measured biometric data and physiological responses while another conducted tests using sensors to track heart rate, brain function and other metrics while in microgravity. The third studied how certain liquids and solids mix in that very weak gravity.

Virgin Galactic livestreamed the flight on its website, showing the moment when the ship released from its carrier plane and the rocket was ignited. The entire trip took about 90 minutes, with the plane’s touchdown on the runway prompting cheers and claps by Virgin Galactic staff.

With the ship’s copilots, it marked the most Italians in space at the same time. Colonel Walter Villadei, a space engineer with the Italian Air Force, celebrated by unfolding an Italian flag while weightless.

Next up for Virgin Galactic will be the first of hundreds of ticket holders, many who have been waiting years for their chance at weightlessness and to see the curvature of the Earth. Those commercial flights are expected to begin in August and will be scheduled monthly, the space tourism company said.

Virgin Galactic has been working for years to send paying passengers on short space trips and in 2021 finally won the federal government’s approval. The company completed its final test fight in May.

The Italian research flight was initially scheduled for the fall of 2021 but Virgin Galactic at the time said it was forced to push back its timeline due to a potential defect in a component used in its flight control system. Then the company spent months upgrading its rocket ship before resuming testing in early 2023.

After reaching an altitude of nearly 15,000 meters, Virgin Galactic’s space plane is released from a carrier aircraft and drops for a moment before igniting its rocket motor. The rocket shuts off once it reaches space, leaving passengers weight before the ship then glides back to the runway at Spaceport America.

Virgin Galactic has sold about 800 tickets over the past decade, with the initial batch going for $200,000 each. Tickets now cost $450,000 per person.

The company said early fliers have already received their seat assignments.
…

Meta Platforms’ Oversight Board on Thursday called for the suspension of Cambodian Prime Minister Hun Sen for six months, saying a video posted on his Facebook page had violated Meta’s rules against violent threats.

The board, which is funded by Meta but operates independently, said the company erred in leaving up the video and ordered its removal from Facebook.

Meta, in a written statement, agreed to take down the video but said it would respond to the recommendation to suspend Hun Sen after a review.

A suspension would silence the prime minister’s Facebook page less than a month before an election in Cambodia, although critics say the poll will be a sham due to Hun Sen’s autocratic rule.

The decision is the latest in a series of rebukes by the Oversight Board over how the world’s biggest social media company handles rule-breaking political leaders and incitement to violence around elections.

The company’s election integrity efforts are in focus as the United States prepares for presidential elections next year.

The board endorsed Meta’s 2021 banishment of former U.S. President Donald Trump – the current front-runner for the 2024 Republican presidential nomination – after the deadly Jan. 6 Capitol Hill riot, but criticized the indefinite nature of his suspension and urged more careful preparation for volatile political situations overall.

Meta reinstated the former U.S. president earlier this year.  

Last week, the board said Meta’s handling of calls for violence after the 2022 Brazilian election continued to raise concerns about the effectiveness of its election efforts.

Hun Sen’s video, broadcast on his official Facebook page in January, showed the prime minister threatening to beat up political rivals and send “gangsters” to their homes, according to the board’s ruling.

Meta determined at the time that the video fell afoul of its rules, but opted to leave it up under a “newsworthiness” exemption, reasoning that the public had an interest in hearing warnings of violence by their government, the ruling said.

The board held that the video’s harms outweighed its news value.
…

LONDON – One of the world’s most common artificial sweeteners is set to be declared a possible carcinogen next month by a leading global health body, according to two sources with knowledge of the process, pitting it against the food industry and regulators.

Aspartame, used in products from Coca-Cola diet sodas to Mars’ Extra chewing gum and some Snapple drinks, will be listed in July as “possibly carcinogenic to humans” for the first time by the International Agency for Research on Cancer (IARC), the World Health Organization’s (WHO) cancer research arm, the sources said.

The IARC ruling, finalized earlier this month after a meeting of the group’s external experts, is intended to assess whether something is a potential hazard or not, based on all the published evidence.

It does not take into account how much of a product a person can safely consume. This advice for individuals comes from a separate WHO expert committee on food additives, known as JECFA (the Joint WHO and Food and Agriculture Organization’s Expert Committee on Food Additives), alongside determinations from national regulators.

However, similar IARC rulings in the past for different substances have raised concerns among consumers about their use, led to lawsuits, and pressured manufacturers to recreate recipes and swap to alternatives. That has led to criticism that the IARC’s assessments can be confusing to the public.

JECFA, the WHO committee on additives, is also reviewing aspartame use this year. Its meeting began at the end of June, and it is due to announce its findings on the same day that the IARC makes public its decision – on July 14.

Since 1981, JECFA has said aspartame is safe to consume within accepted daily limits. For example, an adult weighing 60 kilograms would have to drink between 12 and 36 cans of diet soda – depending on the amount of aspartame in the beverage – every day to be at risk. Its view has been widely shared by national regulators, including in the United States and Europe.

An IARC spokesperson said both the IARC and JECFA committees’ findings were confidential until July, but added they were “complementary,” with IARC’s conclusion representing “the first fundamental step to understand carcinogenicity.” The additives committee “conducts risk assessment, which determines the probability of a specific type of harm (e.g., cancer) to occur under certain conditions and levels of exposure.”

However, industry and regulators fear that holding both processes at around the same time could be confusing, according to letters from U.S. and Japanese regulators seen by Reuters.

“We kindly ask both bodies to coordinate their efforts in reviewing aspartame to avoid any confusion or concerns among the public,” Nozomi Tomita, an official from Japan’s Ministry of Health, Labor and Welfare, wrote in a letter dated March 27 to WHO’s deputy director general, Zsuzsanna Jakab.

The letter, reviewed by Reuters, also called for the conclusions of both bodies to be released on the same day, as is now happening. The Japanese mission in Geneva, where the WHO is based, did not respond to a request for comment.

Debate

The IARC’s rulings can have huge impact. In 2015, its committee concluded that glyphosate is “probably carcinogenic.” Years later, even as other bodies like the European Food Safety Authority (EFSA) contested this assessment, companies were still feeling the effects of the decision. Germany’s Bayer in 2021 lost its third appeal against U.S. court verdicts that awarded damages to customers blaming their cancers on use of its glyphosate-based weedkillers.

The IARC’s decisions have also faced criticism for sparking needless alarm over hard to avoid substances or situations. It has previously put working overnight and consuming red meat into its “probably cancer-causing” class, and using mobile phones as “possibly cancer-causing,” similar to aspartame.

“IARC is not a food safety body, and their review of aspartame is not scientifically comprehensive and is based heavily on widely discredited research,” said Frances Hunt-Wood, the secretary general of the International Sweeteners Association (ISA).

The body, whose members include Mars Wrigley, a Coca-Cola unit and Cargill, said it had “serious concerns with the IARC review, which may mislead consumers.”

Aspartame has been extensively studied for years. Last year, an observational study in France among 100,000 adults showed that people who consumed larger amounts of artificial sweeteners – including aspartame – had a slightly higher cancer risk.

It followed a study from the Ramazzini Institute in Italy in the early 2000s, which reported that some cancers in mice and rats were linked to aspartame.

However, the first study could not prove that aspartame caused the increased cancer risk, and questions have been raised about the methodology of the second study, including by EFSA, which assessed it.

Aspartame is authorized for use globally by regulators who have reviewed all the available evidence, and major food and beverage makers have for decades defended their use of the ingredient. The IARC said it had assessed 1,300 studies in its June review.

Recent recipe tweaks by soft drinks giant Pepsico demonstrate the struggle the industry has when it comes to balancing taste preferences with health concerns. Pepsico removed aspartame from sodas in 2015, bringing it back a year later, only to remove it again in 2020.

Listing aspartame as a possible carcinogen is intended to motivate more research, said the sources close to the IARC, which will help agencies, consumers and manufacturers draw firmer conclusions.

But it will also likely ignite debate once again over the IARC’s role, as well as the safety of sweeteners more generally.

Last month, the WHO published guidelines advising consumers not to use non-sugar sweeteners for weight control. The guidelines caused a furor in the food industry, which argues they can be helpful for consumers wanting to reduce the amount of sugar in their diet. 
…

Geoffrey Hinton, one of the so-called godfathers of artificial intelligence, on Wednesday urged governments to step in and make sure that machines do not take control of society.

Hinton made headlines in May when he announced he had quit Google after a decade of work to speak more freely on the dangers of AI, shortly after the release of ChatGPT captured the imagination of the world.

The highly respected AI scientist, who is based at the University of Toronto, was speaking to a packed audience at the Collision tech conference in the Canadian city.

The conference brought together more than 30,000 startup founders, investors and tech workers, most looking to learn how to ride the AI wave and not hear a lesson on its dangers.

“Before AI is smarter than us, I think the people developing it should be encouraged to put a lot of work into understanding how it might try and take control away,” Hinton said.

“Right now there are 99 very smart people trying to make AI better and one very smart person trying to figure out how to stop it taking over and maybe you want to be more balanced,” he said.

AI could deepen inequality, says Hinton

Hinton warned that the risks of AI should be taken seriously despite his critics who believe he is overplaying the risks.

“I think it’s important that people understand that this is not science fiction, this is not just fearmongering,” he insisted. “It is a real risk that we must think about, and we need to figure out in advance how to deal with it.”

Hinton also expressed concern that AI would deepen inequality, with the massive productivity gain from its deployment going to the benefit of the rich, and not workers.

“The wealth isn’t going to go to the people doing the work. It is going to go into making the rich richer and not the poorer and that’s very bad for society,” he added.

He also pointed to the danger of fake news created by ChatGPT-style bots and said he hoped that AI-generated content could be marked in a way similar to how central banks watermark cash money.

“It’s very important to try, for example, to mark everything that is fake as fake. Whether we can do that technically, I don’t know,” he said.

The European Union is considering such a technique in its AI Act, a legislation that will set the rules for AI in Europe, which is being negotiated by lawmakers.

‘Overpopulation on Mars’

Hinton’s list of AI dangers contrasted with conference discussions that were less over safety and threats, and more about seizing the opportunity created in the wake of ChatGPT.

Venture Capitalist Sarah Guo said doom and gloom talk of AI as an existential threat was premature and compared it to “talking about overpopulation on Mars,” quoting another AI guru, Andrew Ng.

She also warned against “regulatory capture” that would see government intervention protect the incumbents before it had a chance to benefit sectors such as health, education or science.

Opinions differed on whether the current generative AI giants, mainly Microsoft backed OpenAI and Google, would remain unmatched or whether new actors will expand the field with their own models and innovations.

“In five years, I still imagine that if you want to go and find the best, most accurate, most advanced general model, you’re probably going to still have to go to one of the few companies that have the capital to do it,” said Leigh Marie Braswell of venture capital firm Kleiner Perkins.

Zachary Bratun-Glennon of Gradient Ventures said he foresaw a future where “there are going to be millions of models across a network much like we have a network of websites today.”
…

PHNOM PENH, CAMBODIA — Cambodian Prime Minister Hun Sen, a devoted and very active user of Facebook — on which he has posted everything from photos of his grandchildren to threats against his political enemies — said Wednesday that he would no longer upload to the platform and would instead depend on the Telegram app to get his messages across. 

Telegram is a popular messaging app that also has a blogging tool called “channels.” In Russia and some neighboring countries, it is actively used both by government officials and opposition activists for communicating with mass audiences. Telegram played an important role in coordinating unprecedented anti-government protests in Belarus in 2020, and it currently serves as a major source of news about Russia’s war in Ukraine. 

Hun Sen, 70, who has led Cambodia for 38 years, is listed as having 14 million Facebook followers, though critics have suggested a large number of them are merely “ghost” accounts purchased in bulk from so-called “click farms,” an assertion the long-serving prime minister has repeatedly denied. The Facebook accounts of Joe Biden and Donald Trump by comparison boast 11 million and 34 million followers, respectively, though the United States has about 20 times the population of Cambodia. 

Hun Sen officially launched his Facebook page on September 20, 2015, after his fierce political rival, opposition leader Sam Rainsy, effectively demonstrated how it could be used to mobilize support. Hun Sen is noted as a canny and sometimes ruthless politician, and he has since then managed to drive his rival into exile and neutralize all his challengers, even though Cambodia is a nominally democratic state. 

Controversial remarks

Hun Sen said he was giving up Facebook for Telegram because he believed the latter would be more effective for communicating. In a Telegram post on Wednesday, he said it would be easier for him to get his message out when traveling in other countries that officially ban Facebook use, such as China, the top ally of his government. Hun Sen has 855,000 followers so far on Telegram, where he appears to have started posting in mid-May. 

It is possible, however, that Hun Sen’s social media loyalty switch has to do with controversy about remarks he posted earlier this year on Facebook that in theory could see him get at least temporarily banned from the platform very soon. 

In January, speaking at a road construction ceremony, he decried opposition politicians who accused his ruling Cambodian People’s Party of stealing votes. 

“There are only two options. One is to use legal means and the other is to use a stick,” the prime minister said. “Either you face legal action in court, or I rally [the Cambodian] People’s Party people for a demonstration and beat you up.” His remarks were spoken on Facebook Live and kept online as a video. 

Perhaps because of heightened consciousness about the power of social media to inflame and trigger violence in such countries as India and Myanmar, and because the remarks were made ahead of a general election in Cambodia this July, complaints about his words were lodged with Facebook’s parent company, Meta. 

Facebook’s moderators declined to recommend action against Hun Sen, judging that his position as a national leader made his remarks newsworthy and therefore not subject to punishment despite their provocative nature. 

However, the case was forwarded in March to Meta’s Oversight Board, a group of independent experts that is empowered to render an overriding judgment that could limit Hun Sen’s Facebook activities. They are expected to issue a decision on Thursday. The case is being closely watched as an indicator of where Facebook will draw the line in countries with volatile political situations. 

Hun Sen said his Facebook account would remain online, but that he would no longer actively post to it. He urged people looking for news from him to check YouTube and his Instagram account as well as Telegram and said he had ordered his office to establish a TikTok account to allow him to communicate with his country’s youth.
…

U.S. President Joe Biden says he wants to make sure that every American has access to high-speed internet. VOA’s Julie Taboh has our story about the United States’ more than $40 billion-dollar investment to expand the service. (Videographer:  Adam Greenbaum; Produced by Julie Taboh, Adam Greenbaum)    
…

South Korea is changing the way it calculates a person’s age. 

Under a new law that takes effect Wednesday, South Korea is adopting the international method that uses a person’s actual date of birth to determine their age.   

Under its traditional method, South Koreans are considered to be one year old at birth, including their months in the womb, and become a year older every January 1 regardless of their actual date of birth. 

The new law that takes effect Wednesday means all South Koreans will officially become a year or two younger.   

Officials say a separate method of calculation that uses the date a person is born and then adds a year each January 1 will remain in effect for compulsory military service, education and the legal drinking age. 

Some information for this report came from Reuters, Agence France-Presse.  
…

Since the artificial intelligence chatbot ChatGPT launched last fall, a torrent of think pieces and news reports about the ins and outs and ups and downs of generative artificial intelligence has flowed, stoking fears of a dystopian future in which robots take over the world.  

While much of that hype is indeed just hype, a new report has identified immediate risks posed by apps like ChatGPT. Some of those present distinct challenges to journalists and the news industry.  

Published Wednesday by New York University’s Stern Center for Business and Human Rights, the report identified eight risks related to generative artificial intelligence, or AI, including disinformation, cyberattacks, privacy violations and the decay of the news industry.  

The AI debate “is getting a little confused between concerns about existential dangers versus what immediate harms generative AI might entail,” the report’s co-author Paul Barrett told VOA. “We shouldn’t get paralyzed by the question of, ‘Oh my God, will this technology lead to killer robots that are going to destroy humanity?'” 

The systems being released right now are not going to lead to that nightmarish outcome, explained Barrett, who is the deputy director of the Stern Center.  

Instead, the report — which Barrett co-authored with Justin Hendrix, founder and editor of the media nonprofit Tech Policy Press — argues that lawmakers, regulators and the AI industry itself should prioritize addressing the immediate potential risks.  

Safety concerns

Among the most concerning risks are the human-level threats that artificial intelligence may pose to the safety of journalists and activists.  

Doxxing and smear campaigns are already among the many threats that journalists face online over their work. Doxxing is when someone publishes private or identifying information about someone — such as their address or phone number — on the internet.  

But now with generative AI, it will likely be even easier to dox reporters and harass them online, according to Barrett.  

“If you want to set up a campaign like that, you’re going to have to do a lot less work using generative AI systems,” Barrett said. “It’ll be easier to attack journalists.”  

Propaganda easy to make

Disinformation is another primary risk that the report highlights, because generative AI makes it easier to churn out propaganda.  

The report notes that if the Kremlin had access to generative AI in its disinformation campaign surrounding the 2016 U.S. presidential election, Moscow could have launched a more destructive and less expensive influence operation.  

Generative AI “is going to be a huge engine of efficiency, but it’s also going to make much more efficient the production of disinformation,” Barrett said.  

That bears implications for press freedom and media literacy, since studies indicate that exposure to misinformation and disinformation is linked to reduced trust in the media.  

Generative AI may also exacerbate financial issues plaguing newsrooms, according to the report. 

If people ask ChatGPT a question, for instance, and are happy with the summarized answer, they’re less likely to click on other links to news articles. That means shrinking traffic and therefore ad dollars for news sites, the report said.  

But artificial intelligence is far from all bad news for the media industry.  

For example, AI tools can help journalists research by scraping PDF files and analyzing data quickly. Artificial intelligence can also help fact-check sources and write headlines.  

In the report, Barrett and Hendrix caution the government against allowing this new industry to make the same mistakes as were made with social media platforms.  

“Generative AI doesn’t deserve the deference enjoyed for so long by social media companies,” they write.  

They recommend the government enhance federal authority to oversee AI companies and require more transparency from AI companies.  

“Congress, regulators, the public — and the industry, for that matter — need to pay attention to the immediate potential risks,” Barrett said. “And if the industry doesn’t move fast enough on that front, that’s something Congress needs to figure out a way to force them to pay attention to.” 
…

A dangerous and prolonged heat wave blanketed large parts of the southern United States on Tuesday, buckling highways and forcing people to shelter indoors in what scientists called a climate-change supercharged event. 

Excessive heat warnings were in place from Arizona in the southwest to Alabama in the southeast, with south and central Texas and the Lower Mississippi Valley worst hit, the National Weather Service said. 

Victor Hugo Martinez, a 57-year-old foreman who was leading workers repairing a road in Houston, told AFP: “We can’t keep up with it. It’s too much, we have like 10 or 12 spots like this right now.” 

The crew wrapped bandanas around their heads to protect themselves from the blazing heat, with Martinez explaining they made sure to drink plenty of water and take several breaks to protect their health. 

The National Weather Service meanwhile urged Americans in across the South to drink water, stay indoors, and check on vulnerable friends and relatives. 

Andrew Pershing, a scientist with Climate Central, told AFP the “really unusual thing about this event is how big it is, and how long it has lasted.” 

“There have been places in Texas that have had more than two weeks of over 100 degrees Fahrenheit, which are just really unusual temperatures for this time of year even in a region that is used to heat.” 

Extreme weather more likely

Accumulated historic greenhouse emissions made the extreme weather event at least five times more likely than otherwise, according to preliminary calculations by a team led by Pershing. 

The sweltering conditions are expected to expand throughout the South beginning Wednesday and continue into the long July 4 holiday weekend.  

The extreme heat appears to have claimed some lives. 

Last week, a 66-year-old postal worker in Dallas fainted while delivering mail as the heat index hovered around 115 F. He died hours later, the U.S. Postal Service told the media, though the cause of death is still being investigated. 

And on Friday, a 14-year-old boy collapsed from exhaustion while hiking in Big Bend National Park in Texas and later died, according to an official statement. 

His stepfather left the scene to hike back to their vehicle to find help while the teen’s brother attempted to carry him back to the trailhead. The father was later found dead in a car crash. 

Power grid strained

The strain is sure to put the power grid in Texas to the test, as millions of people switch on their air conditioners to cope, with demand peaking around late afternoon. 

ERCOT, the state utility operator, has issued a Weather Watch, calling on individuals and institutions to voluntarily save energy to avoid an emergency, and has so far been able to cope, thanks in part to an increasing contribution from solar power in recent years. 

Public cooling centers run by local authorities or the Red Cross are available for vulnerable people. 

Animals, too, were suffering. The Houston Humane Society said 12 cats and one dog were found dead in an abandoned apartment. The group was able to rescue six cats from the property. 

Air conditioning can be climate feedback loop

Kristina Dahl, principal climate scientist of the Union of Concerned Scientists said that the widespread use of air conditioning was itself a climate feedback loop. 

“We know that one of the most effective things you can do to prevent heat, illness and death during heat waves is to run the air conditioning,” she told AFP.  “And yet if we are not powering that air conditioning with clean renewable energy sources, we are contributing more carbon emissions to the atmosphere which will further worsen heat which will necessitate greater air conditioning use.” 

Recent years have seen an explosion in litigation aimed at shifting the financial responsibility of climate disasters toward fossil fuel companies.  

Last week, a county in the northwestern state of Oregon filed a lawsuit against major fossil fuel companies seeking more than $51 billion over the 2021 “heat dome,” which blighted Canada and the United States.  

“Communities everywhere are now paying the price for the fossil fuel industry’s decades of climate deception and pollution,” Richard Wiles, president of the Center for Climate Integrity, told AFP.   
…

The commission that enforces rules for U.S. elections is not regulating AI-generated deepfakes in political advertising ahead of the 2024 presidential election. Deana Mitchell has the story.
…

The number of different electronic cigarette devices sold in the U.S. has nearly tripled to over 9,000 since 2020, driven almost entirely by a wave of unauthorized disposable vapes from China, according to tightly controlled sales data obtained by The Associated Press.

The numbers demonstrate the Food and Drug Administration’s inability to control the tumultuous vaping market more than three years after declaring a crackdown on kid-friendly flavors.

Most disposables e-cigarettes, which are thrown away when they’re used up, come in sweet, fruity flavors like pink lemonade, gummy bear and watermelon that have made them the favorite tobacco product among teenagers. All of them are technically illegal because they haven’t been authorized by the FDA.

Once a niche market, cheaper disposables made up 40% of the roughly $7 billion retail market for e-cigarettes last year, according to data from analytics firm IRI obtained by the AP. The company’s proprietary data collects barcode scanner sales from convenience stores, gas stations and other retailers.

More than 5,800 unique disposable products are now being sold in numerous flavors and formulations, according to IRI’s data, up 1,500% from 365 in early 2020. That’s when the FDA effectively banned all flavors except menthol and tobacco from cartridge-based e-cigarettes like Juul, the rechargeable device blamed for sparking a nationwide surge in underage vaping.

But the FDA’s policy — formulated under President Donald Trump — excluded disposables, prompting many teens to switch from Juul to the newer flavored products.

“The FDA moves at a ponderous pace and the industry knows that and exploits it,” said Dr. Robert Jackler of Stanford University, who has studied the rise of disposables. “Time and again, the vaping industry has innovated around efforts to remove its youth-appealing products from the market.”

Adding to the challenge, FDA has little visibility into a sprawling industry centered in China’s Shenzhen manufacturing hub. Agency records show that FDA inspectors have only conducted a tiny handful of inspections in China, despite the fact that it produces nearly all e-cigarettes used in the U.S. today.

“FDA theoretically has the authority to inspect foreign manufacturing facilities,” said Patricia Kovacevic, an attorney specializing in tobacco regulation. “But practically speaking, the inspection program that the FDA has in place only happens in the U.S.”

Most disposables mirror a few major brands, such as Elf Bar or Puff Bar, but hundreds of new varieties appear each month. Companies copy each other’s designs, blurring the line between the real and counterfeit. Entrepreneurs can launch a new product by simply sending their logo and flavor requests to Chinese manufacturers, who promise to deliver tens of thousands of devices within weeks.

Under pressure from politicians, parents and major vaping companies, the FDA recently sent warning letters to more than 200 stores selling popular disposables, including Elf Bar, Esco Bar and Breeze. The agency also issued orders blocking imports of those three brands. But IRI data shows those companies accounted for just 14% of disposable sales last year, leaving dozens of other brands untouched, including Air Bar, Mr. Fog, Fume and Kangvape.

FDA’s tobacco director, Brian King, said the agency is “unwavering” in its commitment against illegal e-cigarettes.

“I don’t think there’s any panacea here,” King said. “We follow a comprehensive approach and that involves addressing all entities across the supply chain, from manufacturers to importers to distributors to retailers.”

IRI restricts access to its data, which it sells to companies, investment firms and researchers. A person not authorized to share the information gave access to the AP on condition of anonymity.

IRI declined to comment on or confirm the data, saying the company doesn’t offer such details to news organizations.

To be sure, the FDA has made progress in a mammoth task: processing nearly 26 million product applications submitted by manufacturers hoping to enter or stay on the market. And King said the agency hopes to get back to “true premarket review” once it finishes plowing through that mountain of applications.

Meanwhile, parents, health groups and major vaping companies essentially agree: The FDA must clear the market of flavored disposables.

But lobbying by tobacco giant Reynolds American, maker of Vuse e-cigarettes, has made some advocates wary about pushing the issue. The company petitioned the FDA earlier this year to restrict flavors in all disposable vaping products.

FDA’s King says the agency already has ample authority to regulate disposables.

“There’s no loophole to close,” King said, pointing to FDA’s recent actions against disposable makers.

But King’s predecessor at the FDA says the current situation could have been avoided but for a decision by Trump’s White House to exclude disposables from the 2020 flavor ban.

“It was preventable,” said Mitch Zeller, who retired from the FDA last year. “But I was told there was no appeal.”

In September 2019, Trump announced at a news conference a plan to ban non-tobacco flavors from all e-cigarettes — both reloadable devices and disposables. But his political advisers worried that could alienate voters.

Zeller said he was subsequently informed in December 2019 that the flavor restrictions wouldn’t apply to disposables.

“I told them: ‘It doesn’t take a crystal ball to predict that kids will migrate to the disposable products that are unaffected by this, and you ultimately won’t solve the problem,'” Zeller said.
…

Robot makers who want to explore the oceans are looking to one of Earth’s most successful sea creatures for design inspiration. Steve Baragona reports.
…

Deforestation rates are near record lows in Indonesia, home to the world’s third-largest rainforests.

It’s one of the few bright spots in an otherwise grim annual report, on the loss of forests worldwide, from the environmental research and policy group World Resources Institute.

Overall, the world lost 4.1 million hectares of undisturbed tropical forest last year, an area the size of Switzerland, according to WRI. That’s a 10% increase from 2021. The loss of forest released as much planet-warming carbon dioxide as all the fossil fuels burned in India in 2021.

Deforestation reverses the CO2 removal function that trees perform. It raises local temperatures and disrupts rainfall patterns.

World leaders pledged to end deforestation by the end of the decade during climate negotiations in Glasgow in 2021.

“Are we on track to halt deforestation by 2030? The short answer is a simple no,” Rod Taylor, head of WRI’s forests program, told reporters at a news conference announcing the results.

Deforestation rates

The good news from Indonesia is that government moratoriums on logging and palm oil plantations and increased fire prevention measures have kept forest losses low.

Corporate pledges to end deforestation in the palm oil supply chain also appear to be working, WRI says.

The 230,000 hectares of untouched, primary forest lost last year is a sharp decline from the 2016 peak of 930,000 hectares.

Still, “that’s a pretty big loss,” Arie Rompas, head of the forest campaign for Greenpeace Indonesia, told VOA. “The area lost is about three times the size of the capital, Jakarta.”

Deforestation is still taking place in protected areas, he noted.

Indonesia’s environment ministry released official figures Monday showing far less deforestation than WRI’s. The ministry says 104,000 hectares (256,990 acres) were lost last year, down from 113,500 hectares (280,464 acres) in 2021.

WRI says it is working with the ministry on forest monitoring but describes the partnership as “a work in progress.”

Deforestation rates also have leveled off in neighboring Malaysia, another major palm oil exporter with similar policies and pledges on deforestation. Commitments to end deforestation in the world’s two largest palm oil producers now cover more than four-fifths of their refining capacity, according to WRI.

Brazil tops forest losses

Separately, forest losses increased by 15% in Brazil. The 1.8 million hectare (4.45 million acre) decline in undisturbed forest was the largest since 2005.

Brazil was responsible for 43% of the losses worldwide.

They took place during the last year of President Jair Bolsonaro’s term. He encouraged increased logging, mining and agriculture in the Amazon rainforest.

Brazilian President Luiz Inacio Lula da Silva, known as Lula, took over at the beginning of 2023 and has promised to reverse course.

Earlier in June, Lula released his plan to reach zero deforestation by 2030. The Brazilian space agency, INPE, reported 31% less forest loss in the first five months of 2023 compared to last year.

Experts say Lula’s efforts will face opposition from agribusiness supporters in the legislature.

The second-largest forest losses were in the Democratic Republic of Congo.

Poverty, not commercial agriculture, is the leading driver of deforestation in the DRC, WRI says. Most forests are cleared for small-scale farming and production of charcoal, the main cooking fuel.

The region’s growing population is putting increasing pressure on tropical forests in the Congo Basin, the world’s second largest.

Elsewhere, Bolivia lost the third-largest area of undisturbed forest, and its losses are increasing. The country lost one-third more forest last year than in 2021.

Land clearing for soybeans and other commodity crops is mainly responsible, and Bolivia’s government backs a further increase in large-scale farming. The country is one of the few that did not sign the 2021 Glasgow pledge to end deforestation.

Four of the 10 countries with the highest rates of forest loss are in Latin America.

Commodity crops drive deforestation

Global demand for soybeans, corn, sugar, paper, timber and livestock are the main forces of deforestation worldwide.

Legislation in the European Union will soon prohibit deforestation in supply chains.

Indonesia and Malaysia call the legislation discriminatory.

But WRI’s Taylor said, “It’s an encouraging decision and hopefully it will impact on deforestation rates in the near future.”

He added, “It’s one big market, but there are other markets that haven’t moved on that kind of legislation yet.”

Rio Tuasikal contributed to this report.
…

Which is the longest river in the world, the Nile or the Amazon? The question has fueled a heated debate for years. Now, an expedition into the South American jungle aims to settle it for good.   

Using boats run on solar energy and pedal power, an international team of explorers plans to set off in April 2024 to the source of the Amazon in the Peruvian Andes, then travel nearly 7,000 kilometers (4,350 miles) across Colombia and Brazil, to the massive river’s mouth on the Atlantic.

“The main objective is to map the river and document the biodiversity” of the surrounding ecosystems, the project’s coordinator, Brazilian explorer Yuri Sanada, told AFP.   

The team also plans to make a documentary on the expedition.   

Around 10 people are known to have traveled the full length of the Amazon in the past, but none have done it with those objectives, said Sanada, who runs film production company Aventuras (Adventures) with his wife, Vera. 

Decades-old dispute

The Amazon, the pulsing aorta of the world’s biggest rainforest, has long been recognized as the largest river in the world by volume, discharging more than the Nile, the Yangtze and the Mississippi combined. 

But there is a decades-old geographical dispute over whether it or the Nile is longer, made murkier by methodological issues and a lack of consensus on a very basic question: where the Amazon starts and ends. 

The Guinness Book of World Records awards the title to the African river.

But “which is the longer is more a matter of definition than simple measurement,” it adds in a note. 

The Encyclopedia Britannica gives the length of the Nile as 6,650 kilometers (4,132 miles), to 6,400 kilometers (3,977 miles) for the Amazon, measuring the latter from the headwaters of the Apurimac River in southern Peru. 

In 2014, U.S. neuroscientist and explorer James “Rocky” Contos developed an alternative theory, putting the source of the Amazon farther away, at the Mantaro River in northern Peru. 

If accepted, that would mean the Amazon “is actually 77 kilometers longer than what geographers had thought previously,” he told AFP.  

Challenges could include alligators

Sanada’s expedition will trace both the Apurimac and Mantaro sources. 

One group, guided by Contos, will travel down the Mantaro by white-water raft. The other will travel the banks of the Apurimac on horseback with French explorer Celine Cousteau, granddaughter of legendary oceanographer Jacques Cousteau. 

At the point where the rivers converge, Sanada and two other explorers will embark on the longest leg of the journey, traveling in three custom-made, motorized canoes powered by solar panels and pedals, equipped with a sensor to measure distance.   

“We’ll be able to make a much more precise measurement,” Sanada said.   

The explorers plan to transfer the sustainable motor technology to local Indigenous groups, he added.

The expedition is backed by international groups including The Explorers Club and the Harvard map collection.  

The adventurers will traverse terrain inhabited by anacondas, alligators and jaguars — but none of that scares Sanada, he said

“I’m most afraid of drug traffickers and illegal miners,” he said.   

The boats will be outfitted with a bulletproof cabin, and the team is negotiating with authorities to obtain an armed escort for the most dangerous zones.   

If the expedition is successful, it may be replicated on the Nile. 

Sanada said the debate over the world’s longest river may never be settled. But he is glad the “race” is drawing attention to the Amazon rainforest’s natural riches and the need to protect it as one of the planet’s key buffers against climate change. 

“The Amazon is [here],” he said, “but the consequences of destroying it and the duty to preserve it are everyone’s.”
…

Muhammad Ali Pate, a Harvard professor who has held top health jobs in Nigeria, has relinquished the top job at the Gavi global vaccine alliance, the organization announced Monday.

Pate, a medical doctor trained in internal medicine and infectious disease, was due to assume the helm on August 3, Gavi had announced in February, taking over from U.S. medical epidemiologist Seth Berkley, who had been in charge since 2011.

Pate informed Gavi “that he has taken an incredibly difficult decision to accept a request to return and contribute to his home country, Nigeria,” the statement said, without further details about the decision.

Gavi’s Chief Operating Officer David Marlow will instead assume the position of Interim Chief Executive Officer while a search for a new CEO continues.

The Gavi vaccine alliance is a nonprofit organization created in 2000 to provide an array of vaccines to developing countries.

Gavi says that since its inception, it has provided vaccines to more than 981 million children, “and prevented more than 16.2 million future deaths, helping to halve child mortality in 73 lower-income countries.”

Gavi has taken the lead on the COVAX initiative, alongside the World Health Organization and the Coalition for Epidemic Preparedness Innovations.

The global scheme has so far shipped nearly 1.9 billion COVID-19 vaccines to 146 territories, with the focus on providing donor-funded jabs to the 92 weakest economies.
…

According to the U.N., in 2021, Nigeria had the most child deaths caused by pollution-related pneumonia in the world, at nearly 70 thousand. UNICEF says 40 percent of those deaths are a result of breathing air pollution caused by burning solid cooking fuels in the home. Timothy Obiezu has this report from Abuja, Nigeria.
…

Researchers from the U.S. National Aeronautics and Space Administration are in Australia carrying out research that will help future missions to Mars. The NASA delegation is looking for the earliest signs of life on Earth that will eventually be compared to rocks brought back from Mars.

NASA officials have said that parts of the Pilbara region in Western Australia are like “stepping back in time.” Some areas date to 3.5 billion years old.

In the red Outback dust, they have found some of the earliest evidence of life on Earth — fossils of ancient microorganisms encased in rocks.

The NASA team plans to compare these terrestrial samples with those brought back from Mars to see if they have any similar characteristics. NASA says it could be well over a decade before the Martian rocks are brought to Earth.

Eric Ianson, the director of NASA’s Mars Exploration Program, told the Australian Broadcasting Corp. Monday that Australia’s red dust could yield clues about past life on the Red Planet.

“We are looking at what are called stromatolites, which are actually some of the earliest evidence of life that existed on Earth and there are fossils that are actually captured within the rock. And how this relates to Mars is that we are currently working on bringing samples back from Mars — rock samples back from Mars — and if we see similar patterns and indications, it could indicate that life actually existed in the past on Mars.”

NASA has also indicated that humans could be sent on a mission to Mars by the mid- to late 2030s, although no definite timetable has been set.

Australia has worked with the United States in space for decades, including helping to broadcast the Apollo 11 Moon landing to the world in 1969.

The Tidbinbilla facility near Canberra is the only NASA tracking station still operational in Australia.

Australian engineers and scientists will also have key roles in the Artemis II mission. They are developing a small autonomous rover to be sent to the Moon and also will establish contact with astronauts on the first crewed voyage to the lunar surface since 1972. That mission could take place as early as 2025 or 2026.
…

The next big advance in cancer treatment could be a vaccine.

After decades of limited success, scientists say research has reached a turning point, with many predicting more vaccines will be out in five years.

These aren’t traditional vaccines that prevent disease, but shots to shrink tumors and stop cancer from coming back. Targets for these experimental treatments include breast and lung cancer, with gains reported this year for deadly skin cancer melanoma and pancreatic cancer.

‘We’re getting something to work. Now we need to get it to work better,’ said Dr. James Gulley, who helps lead a center at the National Cancer Institute that develops immune therapies, including cancer treatment vaccines.

More than ever, scientists understand how cancer hides from the body’s immune system. Cancer vaccines, like other immunotherapies, boost the immune system to find and kill cancer cells. And some new ones use mRNA, which was developed for cancer but first used for COVID-19 vaccines.

For a vaccine to work, it needs to teach the immune system’s T cells to recognize cancer as dangerous, said Dr. Nora Disis of UW Medicine’s Cancer Vaccine Institute in Seattle. Once trained, T cells can travel anywhere in the body to hunt down danger.

‘If you saw an activated T cell, it almost has feet,’ she said. ‘You can see it crawling through the blood vessel to get out into the tissues.’

Patient volunteers are crucial to the research.

Kathleen Jade, 50, learned she had breast cancer in late February, just weeks before she and her husband were to depart Seattle for an around-the-world adventure. Instead of sailing their 46-foot boat, Shadowfax, through the Great Lakes toward the St. Lawrence Seaway, she was sitting on a hospital bed awaiting her third dose of an experimental vaccine. She’s getting the vaccine to see if it will shrink her tumor before surgery.

‘Even if that chance is a little bit, I felt like it’s worth it,’ said Jade, who is also getting standard treatment.

Progress on treatment vaccines has been challenging. The first, Provenge, was approved in the U.S. in 2010 to treat prostate cancer that had spread. It requires processing a patient’s own immune cells in a lab and giving them back through IV.

There are also treatment vaccines for early bladder cancer and advanced melanoma.

Early cancer vaccine research faltered as cancer outwitted and outlasted patients’ weak immune systems, said Olja Finn, a vaccine researcher at the University of Pittsburgh School of Medicine.

‘All of these trials that failed allowed us to learn so much,’ Finn said.

As a result, she’s now focused on patients with earlier disease since the experimental vaccines didn’t help with more advanced patients. Her group is planning a vaccine study in women with a low-risk, noninvasive breast cancer called ductal carcinoma in situ.

More vaccines that prevent cancer may be ahead too. Decades-old hepatitis B vaccines prevent liver cancer and HPV vaccines, introduced in 2006, prevent cervical cancer.

In Philadelphia, Dr. Susan Domchek, director of the Basser Center at Penn Medicine, is recruiting 28 healthy people with BRCA mutations for a vaccine test. Those mutations increase the risk of breast and ovarian cancer. The idea is to kill very early abnormal cells, before they cause problems. She likens it to periodically weeding a garden or erasing a whiteboard.

Others are developing vaccines to prevent cancer in people with precancerous lung nodules and other inherited conditions that raise cancer risk.

‘Vaccines are probably the next big thing’ in the quest to reduce cancer deaths, said Dr. Steve Lipkin, a medical geneticist at New York’s Weill Cornell Medicine, who is leading one effort funded by the National Cancer Institute. ‘We’re dedicating our lives to that.’

People with the inherited condition Lynch syndrome have a 60% to 80% lifetime risk of developing cancer. Recruiting them for cancer vaccine trials has been remarkably easy, said Dr. Eduardo Vilar-Sanchez of MD Anderson Cancer Center in Houston, who is leading two government-funded studies on vaccines for Lynch-related cancers.

‘Patients are jumping on this in a surprising and positive way,’ he said.

Drugmakers Moderna and Merck are jointly developing a personalized mRNA vaccine for patients with melanoma, with a large study to begin this year. The vaccines are customized to each patient, based on the numerous mutations in their cancer tissue. A vaccine personalized in this way can train the immune system to hunt for the cancer’s mutation fingerprint and kill those cells. But such vaccines will be expensive.

‘You basically have to make every vaccine from scratch. If this wasn’t personalized, the vaccine could probably be made for pennies, just like the COVID vaccine,’ said Dr. Patrick Ott of Dana-Farber Cancer Institute in Boston.

The vaccines under development at UW Medicine are designed to work for many patients, not just a single patient. Tests are underway in early and advanced breast cancer, lung cancer and ovarian cancer. Some results may come as soon as next year.

Todd Pieper, 56, from suburban Seattle, is participating in testing for a vaccine intended to shrink lung cancer tumors. His cancer spread to his brain, but he’s hoping to live long enough to see his daughter graduate from nursing school next year.

‘I have nothing to lose and everything to gain, either for me or for other people down the road,’ Pieper said of his decision to volunteer.

One of the first to receive the ovarian cancer vaccine in a safety study 11 years ago was Jamie Crase of nearby Mercer Island. Diagnosed with advanced ovarian cancer when she was 34, Crase thought she would die young and had made a will that bequeathed a favorite necklace to her best friend. Now 50, she has no sign of cancer and she still wears the necklace.

She doesn’t know for sure if the vaccine helped, ‘But I’m still here.’
…