Month: November 2018

More than 130,000 people were newly diagnosed with HIV last year in Eastern Europe, the highest rate ever for the region, while the number of new cases in Western Europe declined, global public health experts said on Wednesday.

European Union and European Economic Area countries saw a reduction in 2017 rates, mainly driven by a 20 percent drop since 2015 among men who have sex with men. That left Europe’s overall increasing trend less steep than previously.

All told, almost 160,000 people were diagnosed in Europe with the human immunodeficiency virus (HIV), which causes AIDS, according to data from the European Center for Disease Prevention and Control (ECDC) and the World Health Organization’s (WHO) regional office for Europe.

“It’s hard to talk about good news in the face of another year of unacceptably high numbers of people infected with HIV,” said Zsuzsanna Jakab, director of the WHO regional office.

Calling on governments and health officials to recognize the seriousness of the situation, she urged them: “Scale up your response now.”

The United Nations AIDS agency UNAIDS warned in July that complacency was starting to stall the fight against the global epidemic, with the pace of progress not matching what is needed.

Some 37 million people worldwide are infected with HIV.

The WHO’s European Region is made up of 53 countries with a combined population of nearly 900 million. Around 508 million of those live in the 28 member states of the European Union plus Iceland, Liechtenstein and Norway.

The joint report said one reason for the persistence of HIV in Europe is that many people infected with the virus are diagnosed late, meaning they are more likely to have already passed it on and are also at an advanced stage of infection.

It also found that in the European region, men suffer disproportionately from HIV, with 70 percent of new HIV cases diagnosed in 2017 occurring in men.

Since the start of the AIDS epidemic in the 1980s, more than 77 million people worldwide have become infected with HIV.

Almost half of them – 35.4 million – have died of AIDS.
…

Millions of poor urban children are more likely to die before their fifth birthday than those living in rural areas, according to a U.N. study released Tuesday that challenges popular assumptions behind the global urbanization trend.

The UNICEF research found not all children in cities benefited from the so-called urban advantage — the idea that higher incomes, better infrastructure and proximity to services make for better lives.

“For rural parents, at face-value, the reasons to migrate to cities seem obvious: better access to jobs, health care and education opportunities for their children,” said Laurence Chandy, UNICEF director of data, research and policy.

“But not all urban children are benefiting equally; we find evidence of millions of children in urban areas who fare worse than their rural peers.”

Although most urban children benefit from living in cities, the study identified 4.3 million globally who were more likely to die before age five than their rural counterparts, and said 13.4 million were less likely to complete primary school.

“Children should be a focus of urban planning, yet in many cities they are forgotten, with millions of children cut off from social services in urban slums and informal settlements,” said Chandy in a statement.

About 1 billion people are estimated to live in slums globally, hundreds of millions of them children, according to the U.N. children’s agency.

A decade ago, the world officially became majority urban, and two-thirds of the global population is expected to live in urban areas by 2050, according to the United Nations.

“We applaud UNICEF for putting numbers around a problem that will only get more serious as more and more families move to cities,” said Patrin Watanatada of the Bernard van Leer Foundation, which works to promote early childhood development. “Cities can be wonderful places to grow up, rich with opportunities — but they can also pose serious challenges for a child’s healthy development.”

Poor transport links, limited access to health clinics and parks, as well as growing air pollution and stressed caregivers can exacerbate city living for children, said Watanatada.

Improved walking and cycling infrastructure, affordable housing and transportation, and polices targeted at supporting children and those who care for them could help ease life for urban families.

ICLEI, a global network of more than 1,500 cities, towns and regions, said disasters were more likely to impact the most vulnerable in cities, including children.

“Children are disproportionately affected by gaps in urban services, especially when it comes to water, sanitation, air quality, and food security,” said Yunus Arikan, head of global policy and advocacy at ICLEI.
…

There is a 75 to 80 percent probability of an El Nino weather phenomenon developing within the next three months, the World Meteorological Organization reports.

Global seasonal climate data show precipitation patterns predicted for December to February resemble those normally associated with El Nino, WMO said, adding that it is not expected to be as powerful as the deadly event in 2015 and 2016, which caused droughts, flooding and coral bleaching around the world.

While a weaker El Nino is expected to emerge, WMO scientists warn it still can have a significant impact on rainfall and temperature patterns. They say it could adversely affect agriculture and food security, the management of water resources, and public health.

WMO spokeswoman Claire Nullis tells VOA neutral weather conditions have prevailed for the past few months, with neither El Nino nor its opposite La Nina present. While they are associated with extreme weather events, she says they are not the only factors.

“And we need to bear in mind, we have got climate change,” she said. “So, every El Nino, every La Nina, which takes place now is taking place against a background of the fact that we are living in a dramatically altered climate compared to even 50 years ago. So, the impacts, for instance, on heat waves are likely to be more pronounced than they were several decades ago.”

El Nino and La Nina are phases of what is known as the El Nino-Southern Oscillation cycle, or ENSO. This phenomenon involves fluctuations in temperatures between the ocean and atmosphere in the equatorial Pacific. 

El Nino is sometimes referred to as the warm phase of ENSO, with La Nina acting as its cold opposite. WMO says both events have a major influence on weather and climate patterns over many parts of the world.
…

A Chinese researcher’s surprise claim that he is the first person in the world to successfully edit the genes of a pair of recently born twin girls, making them resistant to HIV, the AIDS virus, has been met with criticism, scorn and denial in China.

Provincial health authorities in the southern province of Guangdong released a statement Tuesday announcing that an investigation into the experiment, which involved seven couples and one successful pregnancy, already is under way and being given utmost attention.

“Results of the investigation will be promptly released to the public,” the statement said.

Continuous denials

China’s Ministry of Health said it was placing a high priority on the case and that it ordered the probe. Meanwhile, those who supposedly were involved in approving an ethical review of the experiment that He Jiankui said he conducted are distancing themselves.

He is an associate professor at the Southern University of Science and Technology, but his employer has said that the researcher has been on leave without pay since February and that the school was not aware of the experiment.

The Shenzhen Health and Family Planning Commission said it had not received an ethical assessment application for the study.

According to a form posted online, the city’s science and innovation committee was listed as backing the experiment, something the panel denies.

The Shenzhen Harmonicare Hospital was listed as having given ethical approval for He’s experiment, although the hospital is denying this.

According to Reuters, Hong Kong-listed Harmonicare Medical Holdings has issued a statement saying the signatures on the form posted online are suspected of having been forged and that “no relevant meeting of the Medical Ethics Committee of the hospital, in fact, took place.”

In its exclusive report on the experiment released Monday, the Associated Press noted that He Jiankui gave official notice of his trial to authorities on November 8, long after his research had begun and during the same month that the two baby girls — Lulu and Nana — were born.

It was clear from He’s interview with AP, that He knew what he was getting himself into. He told AP he was aware of the possible ramifications for future research.

“I feel a strong responsibility that it’s not just to make a first, but also make it an example,” He said.

He currently is in Hong Kong and is expected to deliver a speech at the University of Hong Kong on Wednesday at a summit on human genome editing.

Heated debate

Revelations of the experiment were quickly met with criticism, both and home and abroad, although in China, the pushback was particularly sharp.

Shortly after news broke on Monday, 122 scientists issued an open letter warning that the gene editing tool used in the experiment, the CRISPR-Cas 9 technology, was risky. The scientists also voiced concern the experiment could harm the reputation and development of China’s biomedical community.

The Chinese news website the Paper posted a copy of the statement online in which the scientists said, “Pandora’s box has been opened. We still might have a glimmer of hope to close it before it’s too late.”

They also said the biomedical ethics review for the so-called research existed only in name.

“Conducting direct human experiments can only be described as crazy,” they said.

On social media in China, however, some were optimistic and exuberant about the prospects the claimed breakthrough could bring to fighting disease.

“What is wrong with replacing old humanity with a new humanity? Who doesn’t want to be smarter, live longer, be stronger and healthier?” one post said. “I never expected to see something like Marvel comics in real life…a rebel eccentric scientist as the protagonist who wants to save all human beings.”

Others were worried about the bigger ramifications.

“In the future, humans will create humans and the fatality rate will largely decrease; meanwhile there will be less resources and more competition. We cannot go against natural law,” argued one posting. Another quipped: “For the first time I wish it was an academic fraud.”

Genetic Frankenstein

Liu Wei, a Chinese scientist, said that right now there still are too many uncertainties, adding that the technology has the capability of becoming a genetic version of Frankenstein.

“People are not quite clear about the long-term function of every gene yet. Based on the knowledge we have now, modifying the gene could avoid one disease but may bring about other problems,” Liu noted.

He added that since the technology is cutting-edge there is a big risk those involved in the review process lack the understanding needed, which could lead to negligence.

“If the technology is mature enough, there will definitely be a huge demand in the market to modify the genes of babies, which could lead to black market exchanges and many other challenges,” he said. “We may need more measures to deal with it and simply advocating ethics will not solve the problem.”
…

The United Nations says all countries must triple efforts to cut greenhouse gas emissions to limit an average global temperature increase to two degrees Celsius by 2030.

The ninth annual U.N. Environmental Program Emissions Gap report released Tuesday says emissions in 2030 could be up to 15 billion tons higher than needed to prevent a more than two degree hike.

The report said emissions in 2030 would need to be 55 percent lower than they were in 2017 to limit the average increase to a safer 1.5 degrees.

The 2015 Paris Agreement calls for limiting a temperature rise to between 1.5 and two degrees.

The report said emissions reached a record high of 53.5 tons in 2017 after three years of decreases.

The report also said the world’s 20 largest economies, the Group of Twenty, are not on track to meet their goals in 2030.

The analysis follows a special report last month by the U.N. Intergovernmental Panel on Climate Change.  It concluded that two degrees of warming, once believed to be a safe threshold, would trigger more deadly extreme weather events.  The report said limiting the Earth’s temperature rise to 1.5 degrees would require countries to make rapid and unprecedented changes.

“If the IPCC report represented a global fire alarm, this report is the arson investigation,” said UNEP deputy executive director Joyce Msuya.  “The science is clear; for all the ambitious climate action we have seen, government’s need to move faster and with greater urgency. We are feeding this fire while the means to extinguish it are within reach.”

Friday, U.S. President Donald Trump’s administration issued The National Climate Assessment, which predicts climate change could cost the U.S. hundreds of billions of dollars annually through the end of the century.

Trump, who has vowed to pull the U.S. out of the Paris agreement, has dismissed that prediction, telling a reporter Friday, “I don’t believe it.  No, no, I don’t believe it.”

A U.N. climate conference will be held in Poland December 2-14, when officials will produce a “rule book” on how to implement the Paris agreement.

 
…